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Down-Regulation of HBXIP Inhibits Non-Small Cell Lung Cancer Growth and Enhances the Anti-Tumor Immunity of Mice by Reducing NRP-1
CONCLUSION: Down-regulation of HBXIP reduced Lin28B-mediated NRP-1 to suppress NSCLC cell growth and enhance anti-tumor immunity.PMID:34452886
Source: Annals of Clinical and Laboratory Science - August 28, 2021 Category: Laboratory Medicine Authors: Lulu Wang Mao Sun Xing Lin Yongyang Lei Zhe Yin Wei Zhou Source Type: research
Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis
Autophagy. 2021 Sep 15:1-19. doi: 10.1080/15548627.2021.1965421. Online ahead of print.ABSTRACTEpidemiological and clinical studies have shown that exposure to particulate matter (PM) is associated with an increased incidence of lung cancer and metastasis. However, the underlying mechanism remains unclear. Here, we demonstrated the central role of PM-induced neutrophil recruitment in promoting lung cancer metastasis. We found that reactive oxygen species (ROS)-mediated alveolar epithelial macroautophagy/autophagy was essential for initiating neutrophil chemotaxis and pre-metastatic niche formation in the lungs in response ...
Source: Autophagy - September 15, 2021 Category: Cytology Authors: Jiajun Liu Shumin Li Xuefeng Fei Xi Nan Yingying Shen Huiqing Xiu Stephania A Cormier Chaojie Lu Chuqi Guo Shibo Wang Zhijian Cai Pingli Wang Source Type: research
Down-Regulation of HBXIP Inhibits Non-Small Cell Lung Cancer Growth and Enhances the Anti-Tumor Immunity of Mice by Reducing NRP-1
CONCLUSION: Down-regulation of HBXIP reduced Lin28B-mediated NRP-1 to suppress NSCLC cell growth and enhance anti-tumor immunity.PMID:34452886
Source: Annals of Clinical and Laboratory Science - August 28, 2021 Category: Laboratory Medicine Authors: Lulu Wang Mao Sun Xing Lin Yongyang Lei Zhe Yin Wei Zhou Source Type: research
Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis
Autophagy. 2021 Sep 15:1-19. doi: 10.1080/15548627.2021.1965421. Online ahead of print.ABSTRACTEpidemiological and clinical studies have shown that exposure to particulate matter (PM) is associated with an increased incidence of lung cancer and metastasis. However, the underlying mechanism remains unclear. Here, we demonstrated the central role of PM-induced neutrophil recruitment in promoting lung cancer metastasis. We found that reactive oxygen species (ROS)-mediated alveolar epithelial macroautophagy/autophagy was essential for initiating neutrophil chemotaxis and pre-metastatic niche formation in the lungs in response ...
Source: Autophagy - September 15, 2021 Category: Cytology Authors: Jiajun Liu Shumin Li Xuefeng Fei Xi Nan Yingying Shen Huiqing Xiu Stephania A Cormier Chaojie Lu Chuqi Guo Shibo Wang Zhijian Cai Pingli Wang Source Type: research
Down-Regulation of HBXIP Inhibits Non-Small Cell Lung Cancer Growth and Enhances the Anti-Tumor Immunity of Mice by Reducing NRP-1
CONCLUSION: Down-regulation of HBXIP reduced Lin28B-mediated NRP-1 to suppress NSCLC cell growth and enhance anti-tumor immunity.PMID:34452886
Source: Annals of Clinical and Laboratory Science - August 28, 2021 Category: Laboratory Medicine Authors: Lulu Wang Mao Sun Xing Lin Yongyang Lei Zhe Yin Wei Zhou Source Type: research
Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis
Autophagy. 2021 Sep 15:1-19. doi: 10.1080/15548627.2021.1965421. Online ahead of print.ABSTRACTEpidemiological and clinical studies have shown that exposure to particulate matter (PM) is associated with an increased incidence of lung cancer and metastasis. However, the underlying mechanism remains unclear. Here, we demonstrated the central role of PM-induced neutrophil recruitment in promoting lung cancer metastasis. We found that reactive oxygen species (ROS)-mediated alveolar epithelial macroautophagy/autophagy was essential for initiating neutrophil chemotaxis and pre-metastatic niche formation in the lungs in response ...
Source: Autophagy - September 15, 2021 Category: Cytology Authors: Jiajun Liu Shumin Li Xuefeng Fei Xi Nan Yingying Shen Huiqing Xiu Stephania A Cormier Chaojie Lu Chuqi Guo Shibo Wang Zhijian Cai Pingli Wang Source Type: research
Down-Regulation of HBXIP Inhibits Non-Small Cell Lung Cancer Growth and Enhances the Anti-Tumor Immunity of Mice by Reducing NRP-1
CONCLUSION: Down-regulation of HBXIP reduced Lin28B-mediated NRP-1 to suppress NSCLC cell growth and enhance anti-tumor immunity.PMID:34452886
Source: Annals of Clinical and Laboratory Science - August 28, 2021 Category: Laboratory Medicine Authors: Lulu Wang Mao Sun Xing Lin Yongyang Lei Zhe Yin Wei Zhou Source Type: research
