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Is your kid actin out? A series of six patients with inherited ARPC1B deficiency and review of the literature
CONCLUSION: ARPC1B deficiency has a variable and heterogeneous clinical spectrum, expanded by these cases to include keloid scars and Epstein-Barr virus chronic hepatitis. A novel deletion in exon 8 is shared by three unrelated families and might be the result of a founder effect.PMID:36708766 | DOI:10.1016/j.jaip.2022.12.045
Source: Clinical Lung Cancer - January 28, 2023 Category: Cancer & Oncology Authors: Estefan ía Vásquez-Echeverri Marco Antonio Yamazaki-Nakashimada Edna Venegas Montoya Selma Cecilia Scheffler Mendoza Lina Maria Castano-Jaramillo Edgar Alejandro Medina-Torres Maria Edith Gonz ález-Serrano Melissa Espinosa-Navarro Juan Carlos Bustamant Source Type: research

Allergen immunotherapy, cancer, and immune disorders
Curr Opin Allergy Clin Immunol. 2022 Sep 21. doi: 10.1097/ACI.0000000000000858. Online ahead of print.ABSTRACTPURPOSE OF THE REVIEW: The purpose of this review is to provide an update on the intriguing relationships between allergies, allergen immunotherapy, cancer, and immune disorders. Allergic diseases and cancer are increasing in incidence and prevalence and a potential relationship, or not, between these diseases have been suggested for many years.RECENT FINDINGS: Recent findings suggest that there may be some causative effects between certain types of cancer and allergic diseases, as described in the text. Some types...
Source: Clinical Lung Cancer - September 27, 2022 Category: Cancer & Oncology Authors: David El-Qutob Victor Matheu Enrique Fernandez-Caldas Source Type: research

COVID-19 and lung pathologies
Horm Mol Biol Clin Investig. 2021 Jul 30. doi: 10.1515/hmbci-2020-0096. Online ahead of print.ABSTRACTCOVID-19 is a global emergency with over 10 million cases and over 500, 000 deaths worldwide. The SARS CoV-2 is a RNA virus belonging to the family coronaviridae. It has high infectivity. The manifestations of the disease range from asymptomatic or mild symptoms to severe pneumonia and ARDS. The CT scan of lung shows consolidation and "Ground Glass Opacities". The persons with other comorbidities are considered to be at a higher rate of acquiring the infection. Asthma and other allergies have not been identified as major r...
Source: Clinical Lung Cancer - August 1, 2021 Category: Cancer & Oncology Authors: Darshana Purohit Ashok Kumar Ahirwar Apurva Sakarde Priyanka Asia Niranjan Gopal Source Type: research

COVID-19 vaccination in mastocytosis: recommendations of the European Competence Network on Mastocytosis (ECNM) and American Initiative in Mast Cell Diseases (AIM)
J Allergy Clin Immunol Pract. 2021 Apr 5:S2213-2198(21)00386-X. doi: 10.1016/j.jaip.2021.03.041. Online ahead of print.ABSTRACTMastocytosis is a neoplasm characterized by an accumulation of mast cells in various organs and increased risk for severe anaphylaxis in patients with concomitant allergies. Covid-19 is a pandemic that is associated with a relatively high rate of severe lung disease and mortality. The mortality is particularly high in those with certain comorbidities and increases with age. Recently, several companies have developed an effective vaccination against Covid-19. Although the reported frequency of sever...
Source: Clinical Lung Cancer - April 8, 2021 Category: Cancer & Oncology Authors: Patrizia Bonadonna Knut Brockow Marek Niedoszytko Hanneke Oude Elberink Cem Akin Boguslaw Nedoszytko Joseph H Butterfield Ivan Alvarez-Twose Karl Sotlar Juliana Schwaab Mohamad Jawhar Mariana Castells Wolfgang R Sperr Olivier Hermine Jason Gotlib Roberta Source Type: research

Effects of antioxidant supplements and nutrients on patients with asthma and allergies.
Abstract Asthma and allergic diseases have become a worldwide public health concern because of their increased prevalence. Despite decades of research on risk factors, the causes of these disorders are poorly understood. They are thought to develop through complex interactions between genetic and environmental factors. Because pulmonary and systemic oxidative stress increase inflammatory responses relevant to asthma and allergy, dietary or vitamin supplementation with antioxidants (a broad and varied category) has been proposed as an approach to reducing asthma incidence or morbidity. Meta-analyses of observationa...
Source: Clinical Lung Cancer - May 1, 2014 Category: Cancer & Oncology Authors: Moreno-Macias H, Romieu I Tags: J Allergy Clin Immunol Source Type: research