• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Glutamate quantification in patients with supratentorial gliomas using chemical shift imaging
This study aimed to evaluate and validate chemical shift imaging (CSI) for in vivo glutamate (Glu) quantification in patients with supratentorial gliomas. If validated, CSI could become an extremely useful tool to investigate metabolic dysfunction of Glu in excitotoxic neuropathologies. Quantitative CSI estimates of Glu concentrations were compared with known concentrations of Glu in aqueous phantom solutions. Forty‐one patients with known or likely supratentorial gliomas underwent preoperative CSI. The spectra obtained were analyzed for Glu concentrations and Glu to creatine (Cr) ratios. These in vivo measurements were ...
Source: NMR in Biomedicine - March 24, 2014 Category: Radiology Authors: S. V. Liubinas, K. J. Drummond, P. M. Desmond, A. Bjorksten, A. P. Morokoff, A. H. Kaye, T. J. O'Brien, B. A. Moffat Tags: Research article Source Type: research

Technical considerations on the validity of blood oxygenation level‐dependent‐based MR assessment of vascular deoxygenation
A blood oxygenation level‐dependent (BOLD)‐based apparent relative oxygen extraction fraction (rOEF) as a semi‐quantitative marker of vascular deoxygenation has recently been introduced in clinical studies of patients with glioma and stroke, yielding promising results. These rOEF measurements are based on independent quantification of the transverse relaxation times T2 and T2* and relative cerebral blood volume (rCBV). Simulations demonstrate that small errors in any of the underlying measures may result in a large deviation of the calculated rOEF. Therefore, we investigated the validity of such measurements. For thi...
Source: NMR in Biomedicine - May 9, 2014 Category: Radiology Authors: Nuria M. Hirsch, Vivien Toth, Annette Förschler, Hendrik Kooijman, Claus Zimmer, Christine Preibisch Tags: Research article Source Type: research

Direct saturation ‐corrected chemical exchange saturation transfer MRI of glioma: Simplified decoupling of amide proton transfer and nuclear overhauser effect contrasts
ConclusionThe proposed DISC‐CEST method, by correction of nonlinear direct water saturation effect, serves as a promising alternative to both the commonly used MTRasym and the simplistic three‐offset analyses. It provides simple yet reliable in vivo CEST quantification such as APT and NOE mapping in brain tumor, which is promising for clinical translation. Magn Reson Med, 2017. © 2017 International Society for Magnetic Resonance in Medicine.
Source: Magnetic Resonance in Medicine - October 13, 2017 Category: Radiology Authors: Iris Yuwen Zhou, Enfeng Wang, Jerry S. Cheung, Dongshuang Lu, Yang Ji, Xiaoan Zhang, Giulia Fulci, Phillip Zhe Sun Tags: Rapid Communication Source Type: research

Direct saturation-corrected chemical exchange saturation transfer MRI of glioma: Simplified decoupling of amide proton transfer and nuclear overhauser effect contrasts.
CONCLUSION: The proposed DISC-CEST method, by correction of nonlinear direct water saturation effect, serves as a promising alternative to both the commonly used MTRasym and the simplistic three-offset analyses. It provides simple yet reliable in vivo CEST quantification such as APT and NOE mapping in brain tumor, which is promising for clinical translation. Magn Reson Med, 2017. © 2017 International Society for Magnetic Resonance in Medicine. PMID: 29030880 [PubMed - as supplied by publisher]
Source: Magnetic Resonance in Medicine - October 13, 2017 Category: Radiology Authors: Yuwen Zhou I, Wang E, Cheung JS, Lu D, Ji Y, Zhang X, Fulci G, Sun PZ Tags: Magn Reson Med Source Type: research

How cost-effective is intraoperative MRI for gliomas?
Using a simulated clinical decision analysis model, researchers from the University...Read more on AuntMinnie.comRelated Reading: Workflow optimization cuts MRI turnaround time Imaging analytics platform optimizes MRI operations MRA is cost-effective for kidney disease-related aneurysms Study reveals steep cost of delaying stroke treatment MRI for knee pain adds cost with negligible benefit
Source: AuntMinnie.com Headlines - April 2, 2019 Category: Radiology Source Type: news

Intracranial long-term complications of radiation therapy: an image-based review
ConclusionsWe describe the clinical and imaging features of selected sequelae of intracranial radiation therapy, with a focus on those most relevant to practicing radiologists. Knowledge of these complications and their imaging findings is important, because radiologists play a key role in early detection of these entities.
Source: Neuroradiology - January 4, 2021 Category: Radiology Source Type: research

Clinical and radiological aspects of bilateral temporal abnormalities: pictorial essay
Abstract The temporal lobes are vulnerable to several diseases, including infectious, immune-mediated, degenerative, vascular, metabolic, and neoplastic processes. Therefore, lesions in the temporal lobes can pose a diagnostic challenge for the radiologist. The temporal lobes are connected by structures such as the anterior commissure, corpus callosum, and hippocampal commissure. That interconnectedness favors bilateral involvement in various clinical contexts. This pictorial essay is based on a retrospective analysis of case files from a tertiary university hospital and aims to illustrate some of the conditions that simul...
Source: Radiologia Brasileira - March 26, 2021 Category: Radiology Source Type: research

< mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" > < mml:mrow > < mml:msubsup > < mml:mi > T < /mml:mi > < mml:mn > 2 < /mml:mn > < mml:mo > ' < /mml:mo > < /mml:msubsup > < /mml:mrow > < /mml:math > mapping of the brain from water-unsuppressed < sup > 1 < /sup > H-MRSI  and turbo spin-echo data
CONCLUSIONS: High-quality T 2 ' $$ {\mathrm{T}}_2^{\prime } $$ maps can be obtained from water-unsuppressed 1 H-MRSI and TSE data using the proposed method. With further development, this method may lay a foundation for simultaneously imaging oxygenation and neurometabolic alterations of brain disorders.PMID:35844075 | DOI:10.1002/mrm.29386
Source: Magnetic Resonance in Medicine - July 18, 2022 Category: Radiology Authors: Tianxiao Zhang Rong Guo Yudu Li Yibo Zhao Yao Li Zhi-Pei Liang Source Type: research