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Cancers, Vol. 11, Pages 404: Allergic Signs in Glioma Pathology: Current Knowledge and Future Perspectives
aro Historically restrained to immune defense against parasite infections, allergic inflammation has been recently rediscovered to protect from a wide array of environmental triggers, such as xenobiotics and carcinogens, which can induce DNA damage and ultimately lead to cancer development. Moreover, cells and mediators typical of allergic responses can importantly modulate the tissue inflammatory milieu, which represents a crucial gatekeeper towards the acquisition of malignancy by cancer cells through immune escape. Numerous studies have described an inverse association between allergies and glioma development. Mast ...
Source: Cancers - March 21, 2019 Category: Cancer & Oncology Authors: Massimo Costanza Gaetano Finocchiaro Tags: Review Source Type: research