• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Pre ‐diagnostic levels of sVEGFR2, sTNFR2, sIL‐2Rα and sIL‐6R are associated with glioma risk: A nested case–control study of repeated samples
In a nested case –control study, we found that the pre-diagnostic levels of sVEGFR2, sTNFR2, sIL-2Rα and sIL-6R were associated with glioma risk. Our findings suggest these proteins play important roles in gliomagenesis. AbstractNo strong aetiological factors have been established for glioma aside from genetic mutations and variants, ionising radiation and an inverse relationship with asthmas and allergies. Our aim was to investigate the association between pre-diagnostic immune protein levels and glioma risk. We conducted a case –control study nested in the Northern Sweden Health and Disease Study cohort. We analysed...
Source: Cancer Medicine - January 14, 2022 Category: Cancer & Oncology Authors: Wendy Yi ‐Ying Wu, Florentin Späth, Carl Wibom, Benny Björkblom, Anna M. Dahlin, Beatrice Melin Tags: RESEARCH ARTICLE Source Type: research

Autoimmune diseases and immunosuppressive therapy in relation to the risk of glioma
The immune system is increasingly recognized as a key player in glioma pathobiology. Small case ‐control studies have found inverse associations between autoimmune diseases and glioma incidence. We performed a large case‐control study, which did not replicate these associations. However, our data indicate that inflammatory bowel disease (IBD) among patients ≤40 years are associated with an increased risk of glioma. Further studies are needed to explore the role of IBD and altered microbiota in glioma. AbstractEffectors from the immune system can modulate the course and possibly the early development of gliomas. We, ...
Source: Cancer Medicine - December 9, 2019 Category: Cancer & Oncology Authors: Tareq M. Anssar, Michael F. Leitzmann, Ralf A. Linker, Christoph Meier, Claudia Becker, Susan Jick, Katharina Sahm, Michael Platten, Peter Hau, Corinna Seliger Tags: ORIGINAL RESEARCH Source Type: research