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Cancer: Glioma
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Autoimmune diseases and immunosuppressive therapy in relation to the risk of glioma
The immune system is increasingly recognized as a key player in glioma pathobiology. Small case ‐control studies have found inverse associations between autoimmune diseases and glioma incidence. We performed a large case‐control study, which did not replicate these associations. However, our data indicate that inflammatory bowel disease (IBD) among patients ≤40 years are associated with an increased risk of glioma. Further studies are needed to explore the role of IBD and altered microbiota in glioma. AbstractEffectors from the immune system can modulate the course and possibly the early development of gliomas. We, ...
Source: Cancer Medicine - December 9, 2019 Category: Cancer & Oncology Authors: Tareq M. Anssar,
Michael F. Leitzmann,
Ralf A. Linker,
Christoph Meier,
Claudia Becker,
Susan Jick,
Katharina Sahm,
Michael Platten,
Peter Hau,
Corinna Seliger Tags: ORIGINAL RESEARCH Source Type: research
