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Interactions of Betel Quid Constituents with Drug Disposition Pathways: An Overview
Curr Drug Metab. 2023 Feb 28. doi: 10.2174/1389200224666230228142052. Online ahead of print.ABSTRACTGlobal estimates indicate that over 600 million individuals worldwide consume the areca (betel) nut in some form. Nonetheless, its consumption is associated with a myriad of oral and systemic ailments, such as pre-cancerous oral lesions, oropharyngeal cancers, liver toxicity and hepatic carcinoma, cardiovascular distress, and addiction. Users commonly chew sliver nuts in a complex consumable preparation called betel quid (BQ). Consequently, the user is exposed to a wide array of chemicals with diverse pharmacokinetic behavio...
Source: Current Drug Metabolism - February 28, 2023 Category: Drugs & Pharmacology Authors: Jasmine Canlas Alan L Myers Source Type: research