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Cancer: Adenocarcinoma
Therapy: Statin Therapy
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Total 36 results found since Jan 2013.
Statins Inhibit Inflammatory Cytokine Production by Macrophages and Acinar-to-Ductal Metaplasia of Pancreatic Cells
CONCLUSION: Our data support the hypothesis that statins oppose early PDAC development by their effects on macrophages and ADM formation. The inhibitory actions of statins on macrophages may collaborate with direct inhibitory effects on transformed pancreatic epithelial cells, which cumulatively may reduce early PDAC development and progression.PMID:36313271 | PMC:PMC9615480 | DOI:10.1016/j.gastha.2022.04.012
Source: Adv Data - October 31, 2022 Category: Epidemiology Authors: Soichiro Ako Yaroslav Teper Linda Ye James Sinnett-Smith Oscar J Hines Enrique Rozengurt Guido Eibl Source Type: research
Barrett Esophagus: Rapid Evidence Review
Am Fam Physician. 2022 Oct;106(4):383-387.ABSTRACTBarrett esophagus is a premalignant change of the esophagus; however, malignant transformation to esophageal adenocarcinoma is rare in patients without dysplasia. Barrett esophagus is estimated to affect up to 5.6% of the U.S. population. Risk factors for Barrett esophagus include gastroesophageal reflux disease, obesity, age older than 50 years, male sex, tobacco use, and a family history of Barrett esophagus or esophageal adenocarcinoma. Patients who experience chronic gastroesophageal reflux symptoms plus additional risk factors should be considered for screening. Mucosa...
Source: American Family Physician - October 19, 2022 Category: Primary Care Authors: Carl Bryce Merima Bucaj Renee Gazda Source Type: research
