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Diversity of Organism-Wide and Organ-Specific Endothelial Cells
AbstractPurpose of ReviewEndothelial cells are of great importance in many types of diseases including the coronary artery diseases in heart and stroke in brain. In this review, we explore the heterogeneity among endothelial cells from an organism-wide, organ-specific, and healthy versus disease perspective.Recent FindingsRecent studies addressing the cellular heterogeneity between arterial versus venous endothelial cells (ECs) have revealed that arterial ECs have tighter junctions, a decreased immune response, anticoagulant properties while veins have both anticoagulant and procoagulant properties. Blood and lymphatic ECs...
Source: Current Cardiology Reports - February 7, 2020 Category: Cardiology Source Type: research