Filtered By:
Cancer: Brain Cancers
Drug: Metformin
Countries: Switzerland Health
This page shows you your search results in order of date.
Order by Relevance | Date
Total 1 results found since Jan 2013.
Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice
This study was aimed at evaluating the effects of MET on lipopolysaccharide (LPS)-induced systemic and neuroinflammation, oxidative stress, and behavioural changes. The study consisted of six groups, where three selected doses of MET (100, 200, and 300 mg/kg) were employed in male Swiss albino mice, with one group of imipramine (IMI), saline, and LPS each. Systemic inflammation was induced by injecting LPS (1.5 mg/kg) by intraperitoneal route. A battery of behavioural tests including open field, forced swim, and tail suspension tests were emplo yed to assess the impact of systemic inflammation on exploratory behaviour a...
Source: Inflammopharmacology - September 2, 2019 Category: Drugs & Pharmacology Source Type: research
