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Cancer: Bladder Cancer
Nutrition: Zinc
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Total 80 results found since Jan 2013.
Gene of the month: GATA3
J Clin Pathol. 2023 Sep 19:jcp-2023-209017. doi: 10.1136/jcp-2023-209017. Online ahead of print.ABSTRACTGATA binding protein 3 (GATA3) is a zinc-finger pioneer transcription factor involved in diverse processes. GATA3 regulates gene expression through binding nucleosomal DNA and facilitating chromatin remodelling. Post-translational modifications modulate its activity. During development, GATA3 plays a key role in cell differentiation. Mutations in GATA3 are linked to breast and bladder cancer. GATA3 expression is a feature of the luminal subtype of bladder cancer and has implications for immune status and therapeutic resp...
Source: Clinical Genitourinary Cancer - September 19, 2023 Category: Cancer & Oncology Authors: Zekai Qiang Ibrahim Jubber Kirsty Lloyd Marcus Cumberbatch Jon Griffin Source Type: research
Arsenic and cancer: Evidence and mechanisms
Adv Pharmacol. 2023;96:151-202. doi: 10.1016/bs.apha.2022.08.001. Epub 2022 Sep 27.ABSTRACTArsenic is a potent carcinogen and poses a significant health concern worldwide. Exposure occurs through ingestion of drinking water and contaminated foods and through inhalation due to pollution. Epidemiological evidence shows arsenic induces cancers of the skin, lung, liver, and bladder among other tissues. While studies in animal and cell culture models support arsenic as a carcinogen, the mechanisms of arsenic carcinogenesis are not fully understood. Arsenic carcinogenesis is a complex process due its ability to be metabolized an...
Source: Advances in Pharmacology - March 1, 2023 Category: Drugs & Pharmacology Authors: Rachel M Speer Xixi Zhou Lindsay B Volk Ke Jian Liu Laurie G Hudson Source Type: research
