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Cancer: Squamous Cell Carcinoma
Drug: Acetic Acid
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Total 16 results found since Jan 2013.
Clinical analysis of immune function and intestinal flora changes in patients with oral squamous carcinoma before and after treatment
CONCLUSIONS: Conventional treatment remarkably enhances immune function, revitalizes the distribution of intestinal microflora, elevates the content of short-chain fatty acids in the intestine of OSCC patients, thereby improving the patients' health.PMID:36758602
Source: Shanghai Journal of Stomatology - February 9, 2023 Category: Dentistry Authors: Yi Qian Chao Deng Xiao-Bo Xu Ye-Jun Chen Yun-Ping Hu Li-Lin Hong Da-Jun Feng Source Type: research
Potential of unglycosylated horseradish peroxidase variants for enzyme prodrug cancer therapy
In this study, we generated recombinant, unglycosylated HRP variants in Escherichia coli using random mutagenesis and investigated their biochemical properties and suitability for cancer treatment. The cytotoxicity of the HRP-IAA enzyme prodrug system was assessed in vitro with HCT-116 human colon, FaDu human nasopharyngeal squamous cell carcinoma and murine colon adenocarcinoma cells (MC38). Extensive cytotoxicity was shown in all three cancer cell lines: the cell viability of HCT-116 and MC38 cells treated with HRP-IAA was below 1% after 24 h incubation and the surviving fraction of FaDu cells was ≤ 10% after 72 h. How...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - August 15, 2021 Category: Drugs & Pharmacology Authors: Diana Humer Valentina Furlanetto Anna-Katharina Schruef Angelika Wlodarczyk Mario Kuttke Christina Divne Oliver Spadiut Source Type: research
