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Cancer: Leukemia
Drug: Magnesium

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Total 27 results found since Jan 2013.

A Comparison of Doxorubicin-Resistant Colon Cancer LoVo and Leukemia HL60 Cells: Common Features, Different Underlying Mechanisms
Curr Issues Mol Biol. 2021 May 22;43(1):163-175. doi: 10.3390/cimb43010014.ABSTRACTChemoresistance causes cancer relapse and metastasis, thus remaining the major obstacle to cancer therapy. While some light has been shed on the underlying mechanisms, it is clear that chemoresistance is a multifaceted problem strictly interconnected with the high heterogeneity of neoplastic cells. We utilized two different human cell lines, i.e., LoVo colon cancer and promyelocytic leukemia HL60 cells sensitive and resistant to doxorubicin (DXR), largely used as a chemotherapeutic and frequently leading to chemoresistance. LoVo and HL60 res...
Source: Current Issues in Molecular Biology - June 2, 2021 Category: Molecular Biology Authors: Laura Locatelli Alessandra Cazzaniga Giorgia Fedele Monica Zocchi Roberta Scrimieri Claudia Moscheni Sara Castiglioni Jeanette A Maier Source Type: research