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Informatics and Computational Methods in Natural Product Drug Discovery: A Review and Perspectives
Joseph D. Romano1,2,3,4 and Nicholas P. Tatonetti1,2,3,4* 1Department of Biomedical Informatics, Columbia University, New York, NY, United States 2Department of Systems Biology, Columbia University, New York, NY, United States 3Department of Medicine, Columbia University, New York, NY, United States 4Data Science Institute, Columbia University, New York, NY, United States The discovery of new pharmaceutical drugs is one of the preeminent tasks—scientifically, economically, and socially—in biomedical research. Advances in informatics and computational biology have increased productivity at many ...
Source: Frontiers in Genetics - April 29, 2019 Category: Genetics & Stem Cells Source Type: research

Repeated Changes to the Gravitational Field Negatively Affect the Serum Concentration of Select Growth Factors and Cytokines
This study was carried out in accordance with the recommendations of the ethical committee of the Ruhr-Universität Bochum with written informed consent from all subjects. All subjects gave written informed consent in accordance with the Declaration of Helsinki. The protocol was approved by the ethical committee of the Ruhr-Universität Bochum (Register-Number 5158–14). Author Contributions US, FS, LG, and AK performed the experiments. US and TR analyzed the data, created the figures, and drafted the manuscript. TW, FS, and NB designed the study. All authors revised the manuscript and approved its fina...
Source: Frontiers in Physiology - April 16, 2019 Category: Physiology Source Type: research

2017 ’ s Year In Health News: Medical Breakthroughs, Opioid Crisis And More
CBS Local — There’s been plenty of progress in the medical world this year, and as a result we now know that more Americans than ever have high blood pressure, but also that coffee everyday is actually good for you. Here’s a look back at the year in health. Opioid Crisis The opioid crisis has dominated much of the health news cycle. President Trump declared the opioid crisis a national emergency earlier this year. Drug overdoses are now the leading cause of death for people under 50 in the United States. New Guidelines for High Blood Pressure The American Heart Association revised its guidelines for high ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - December 20, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News best of 2017 Samantha Lazarus Bennet Source Type: news

A Scalable Framework to Detect Personal Health Mentions on Twitter
Conclusions: It is possible to automatically detect personal health status mentions on Twitter in a scalable manner. These mentions correspond to the health issues of the Twitter users themselves, but also other individuals. Though this study did not investigate the veracity of such statements, we anticipate such information may be useful in supplementing traditional health-related sources for research purposes.
Source: Journal of Medical Internet Research - June 5, 2015 Category: Journals (General) Authors: Zhijun YinDaniel FabbriS Trent RosenbloomBradley Malin Source Type: research