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Total 470 results found since Jan 2013.

Late‐onset primary antiphospholipid syndrome in the elderly: a report of seven cases
ConclusionIn this report, we report on primary APS in the elderly, to discuss its prevalence and the clinical significance of positive antiphospholipid antibodies in subjects over the age of 65 years.
Source: APLAR Journal of Rheumatology - December 20, 2014 Category: Rheumatology Authors: Yosra Cherif, Moez Jallouli, Hela Hriz, Radhouane Gouiaa, Sameh Marzouk, Mouna Snoussi, Faten Frikha, Hatem Masmoudi, Zouhir Bahloul Tags: Original Article Source Type: research

The global impact of non-communicable diseases on households and impoverishment: a systematic review
Abstract The global economic impact of non-communicable diseases (NCDs) on household expenditures and poverty indicators remains less well understood. To conduct a systematic review and meta-analysis of the literature evaluating the global economic impact of six NCDs [including coronary heart disease, stroke, type 2 diabetes mellitus (DM), cancer (lung, colon, cervical and breast), chronic obstructive pulmonary disease (COPD) and chronic kidney disease (CKD)] on households and impoverishment. Medline, Embase and Google Scholar databases were searched from inception to November 6th 2014. To identify additional publ...
Source: European Journal of Epidemiology - December 20, 2014 Category: Epidemiology Source Type: research

High-Fiber Diet Linked To Lower Risk Of Death In Study Of Nearly 1 Million People
By Shereen Lehman (Reuters Health) - People who ate the most fiber were less likely to die of any cause during a recent study of nearly one million people. The finding might be explained by fiber's potential to lower the risk of chronic diseases including heart disease, stroke, diabetes and several types of cancer, researchers say. Individuals should be encouraged to increase their dietary fiber intake "to potentially decrease the risk of premature death," Yang Yang, of the Shanghai Cancer Institute in China, and colleagues write in the American Journal of Epidemiology. They pooled data ...
Source: Science - The Huffington Post - January 12, 2015 Category: Science Source Type: news

The global impact of non-communicable diseases on healthcare spending and national income: a systematic review
Abstract The impact of non-communicable diseases (NCDs) in populations extends beyond ill-health and mortality with large financial consequences. To systematically review and meta-analyze studies evaluating the impact of NCDs (including coronary heart disease, stroke, type 2 diabetes mellitus, cancer (lung, colon, cervical and breast), chronic obstructive pulmonary disease and chronic kidney disease) at the macro-economic level: healthcare spending and national income. Medical databases (Medline, Embase and Google Scholar) up to November 6th 2014. For further identification of suitable studies, we searched refere...
Source: European Journal of Epidemiology - January 18, 2015 Category: Epidemiology Source Type: research

HRT increases ovarian cancer risk by small amount
Conclusion This systematic review and meta-analysis showed that ovarian cancer risk was significantly increased in current HRT users, even in those with less than five years of HRT use (the average was three years). In ex-users, risks decreased the longer ago HRT use had stopped, but risks during the first few years after stopping remained significant. Furthermore, about a decade after stopping, long-duration hormone therapy use (average nine years of HRT use), there still seemed to be a small excess risk. The review has a few limitations, however. The main one is that the review was heavily influenced by just two of t...
Source: NHS News Feed - February 13, 2015 Category: Consumer Health News Tags: Cancer Medication Older people Source Type: news

Hormone replacement therapy might raise stroke risk
Women taking hormone replacement therapy for menopause symptoms might be putting their heart at risk. And, a study finds vegetarianism linked with a lower risk of colorectal cancer. Eboni Williams has some of the day's top medical stories.
Source: Health News: CBSNews.com - March 10, 2015 Category: Consumer Health News Source Type: news

Overweight and obesity on the island of Ireland: an estimation of costs
Conclusions The costs are substantial, and urgent public health action is required in Ireland to address the problem of increasing prevalence of overweight and obesity, which if left unchecked will lead to unsustainable cost escalation within the health service and unacceptable societal costs.
Source: BMJ Open - March 16, 2015 Category: Journals (General) Authors: Dee, A., Callinan, A., Doherty, E., O'Neill, C., McVeigh, T., Sweeney, M. R., Staines, A., Kearns, K., Fitzgerald, S., Sharp, L., Kee, F., Hughes, J., Balanda, K., Perry, I. J. Tags: Open access, Epidemiology, Health economics Research Source Type: research

Precision medicine is coming, but not anytime soon
President Obama’s announcement of a Precision Medicine Initiative was one of the few items in this year’s State of the Union address to garner bipartisan support. And for good reason. Precision medicine, also known as personalized medicine, offers the promise of health care — from prevention to diagnosis to treatment — based on your unique DNA profile. Who wouldn’t want that? We’ve already had a taste of precision medicine. Relatively low-tech therapies like eyeglasses, orthotic devices, allergy treatments, and blood transfusions have long been personalized for the individual. Genetic analysis o...
Source: New Harvard Health Information - March 26, 2015 Category: Consumer Health News Authors: Beverly Merz Tags: Health care personalized health care precision medicine Source Type: news

Fit middle-aged men have lower cancer risk
Conclusion This study shows that cardiovascular fitness is likely to reduce men's chances of developing lung and colorectal cancer, and appears to boost survival from cancer or cardiovascular disease in those diagnosed after the age of 65. This was based on comparing the top 40% of fittest men with the 20% least fit. The study focused on fitness and took account of major risk factors for cancer, such as smoking and blood pressure. However, it left out one important risk factor: diet. What people eat and drink is known to affect cancer risk. The fittest group may also have been the healthiest in terms of eating well and ...
Source: NHS News Feed - March 27, 2015 Category: Consumer Health News Tags: Cancer Lifestyle/exercise Source Type: news

HyDRA: gene prioritization via hybrid distance-score rank aggregation
Summary: Gene prioritization refers to a family of computational techniques for inferring disease genes through a set of training genes and carefully chosen similarity criteria. Test genes are scored based on their average similarity to the training set, and the rankings of genes under various similarity criteria are aggregated via statistical methods. The contributions of our work are threefold: (i) first, based on the realization that there is no unique way to define an optimal aggregate for rankings, we investigate the predictive quality of a number of new aggregation methods and known fusion techniques from machine lea...
Source: Bioinformatics - April 2, 2015 Category: Bioinformatics Authors: Kim, M., Farnoud, F., Milenkovic, O. Tags: SYSTEMS BIOLOGY Source Type: research

Does Thoracoscopic Surgery Decrease the Morbidity of Combined Lung and Chest Wall Resection?
Conclusions Thoracoscopic chest wall resection was feasible, expanded our case selection, and reduced prosthetic reconstruction. It did not, however, protect frail, elderly patients reliably. Briefer, less traumatic operations may be needed for this cohort.
Source: The Annals of Thoracic Surgery - April 24, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Prompting Primary Care Providers about Increased Patient Risk As a Result of Family History: Does It Work?
Conclusions: No change occurred upon instituting simple, at-the-visit family history prompts geared to improve PCPs' ability to identify patients at high risk for 6 common conditions. The results are both surprising and disappointing. Further studies should examine physicians' perception of the utility of prompts for family history risk.
Source: Journal of the American Board of Family Medicine - May 8, 2015 Category: Primary Care Authors: Zazove, P., Plegue, M. A., Uhlmann, W. R., Ruffin, M. T. Tags: Original Research Source Type: research

7 Big Things We Learned About Sleep In The Past Decade
It's no secret that here at The Huffington Post, we love sleep -- and for good reason. Sleep has been called the "third pillar" of health, along with nutrition and exercise. Getting the quality sleep that you need has the power to protect your physical and mental health, while skipping out on sleep can seriously hurt your health, cognition and well-being over time. Over the past 10 years, sleep has finally become widely recognized as a critical aspect of good health, and new research has shed more light on its importance in our lives. Here's what we've learned. 1. A sleeping brain is an active brain. While you're re...
Source: Science - The Huffington Post - May 25, 2015 Category: Science Source Type: news