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Survivors of childhood cancer have high-risk of recurrent stroke
(University of California - San Francisco) A new study from the UCSF Pediatric Brain Center shows that childhood cancer survivors suffering one stroke have double the risk of suffering a second stroke, when compared with non-cancer stroke survivors.
Source: EurekAlert! - Cancer - August 26, 2015 Category: Cancer & Oncology Source Type: news

Genetic variant linked to increased stroke risk in childhood cancer survivors treated with CRT
(American Association for Cancer Research) A common single nucleotide polymorphism (SNP) was associated with increased risk for developing stroke in childhood survivors who received cranial radiation therapy (CRT) for their primary cancer, according to results presented at the AACR Annual Meeting 2019, March 29-April 3.
Source: EurekAlert! - Cancer - April 2, 2019 Category: Cancer & Oncology Source Type: news

Drugs against alpha-ketoglutarate may combat deadly childhood brain tumor
(NIH/National Institute of Neurological Disorders and Stroke) Every year, 150 to 300 children in the United States are diagnosed with diffuse intrinsic pontine gliomas (DIPGs), aggressive and lethal tumors that grow deep inside the brain, for which there are no cures. In a study funded by the National Institutes of Health, researchers showed that experimental drugs designed to lower the body's natural production of alpha-ketoglutarate extended the lives of mice harboring DIPG tumors by slowing the growth of the cancer cells.
Source: EurekAlert! - Cancer - August 18, 2020 Category: Cancer & Oncology Source Type: news

Optic nerve firing may spark growth of vision-threatening childhood tumor
(NIH/National Institute of Neurological Disorders and Stroke) In a study of mice, researchers showed how the act of seeing light may trigger the formation of vision-harming tumors in young children who are born with neurofibromatosis type 1 (NF1) cancer predisposition syndrome. The research team, funded by the National Institutes of Health, focused on tumors that grow within the optic nerve, which relays visual signals from the eyes to brain. They discovered that the neural activity which underlies these signals can both ignite and feed the tumors.
Source: EurekAlert! - Cancer - June 1, 2021 Category: Cancer & Oncology Source Type: news