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Cancer: Non-Small Cell Lung Cancer
Drug: Temodar
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Total 41 results found since Jan 2013.
First Report of Management of Sequential Small Cell Transformation and ALK I1171T Mutation as Resistance Mechanisms in a Patient With ALK-EML4 Fused Non-Small Cell Lung Adenocarcinoma With a Novel Combination of Temozolomide and Lorlatinib: A Case Report
JTO Clin Res Rep. 2023 Jun 15;4(7):100536. doi: 10.1016/j.jtocrr.2023.100536. eCollection 2023 Jul.ABSTRACTALK-EML4 fusion-positive lung adenocarcinomas (LUADs) are effectively treated with ALK tyrosine kinase inhibitors, but most patients eventually develop resistance to these drugs owing to ALK-dependent or independent mechanisms. Endothelial to mesenchymal transformation with SCLC development is an ALK-independent mechanism of resistance that has not been previously reported with sequential ALK I1171T mutation while the patient is on treatment for the SCLC. Here, we report the first case of sequential SCLC transformatio...
Source: Cell Research - July 17, 2023 Category: Cytology Authors: Umair Majeed Shenduo Li Karan Seegobin Aziza Nassar Rami Manochakian Yujie Zhao Yanyan Lou Source Type: research
Retraction statement: Ding, J., Wang, X., Gao, J. and Song, T. (2021), Silencing of cystatin SN abrogates cancer progression and stem cell properties in papillary thyroid carcinoma. FEBS Open Bio, 11: 2186-2197
FEBS Open Bio. 2023 Aug;13(8):1540. doi: 10.1002/2211-5463.13664. Epub 2023 Jul 6.ABSTRACThttps://doi.org/10.1002/2211-5463.13221 The above article, published online on 08 June 2021 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, the Editor-in-Chief Miguel De la Rosa, FEBS Press, and John Wiley and Sons Ltd. The retraction has been agreed following an investigation into concerns raised by a third party, which revealed inappropriate duplications between this and articles that were either previously published or published later in the same year [1-9]. Thus, the editors c...
Source: Genetics and Molecular Research - July 6, 2023 Category: Genetics & Stem Cells Source Type: research
