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Source: The Turkish Journal of Gastroenterology
Cancer: Liver Cancer

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Total 460 results found since Jan 2013.

Liver Transplantation for Hepatocellular Carcinoma in Patients with Inherited Metabolic Liver Diseases: A Single-Center Analysis
CONCLUSION: Liver transplant for these categories of patients is associated with good disease-free and overall survival, even in the presence of some seemingly poor prognostic features.PMID:37681267 | DOI:10.5152/tjg.2023.22679
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: İbrahim Umar Garzali Abdirahman Sakulen Hargura Volkan İnce Fatma İlknur Varol Brian I Carr Sezai Y ılmaz Source Type: research

SIX1 Downregulation Suppresses Self-renewal Capacity and THY1 Expression in Hepatocellular Carcinoma and SIX1 Dominate the Survival in Liver Cancer
CONCLUSION: The results of this study showed that the knockdown of sine oculis homeoprotein 1 expression might help to prevent hepatocarcinogenesis by increasing drug sensitivity and controlling tumor sphere formation. Overall, these results indicated that sine oculis homeoprotein 1 expression might be useful as a diagnostic marker for patients with hepatocellular carcinoma.PMID:37427884 | DOI:10.5152/tjg.2023.22293
Source: The Turkish Journal of Gastroenterology - July 10, 2023 Category: Gastroenterology Authors: Pelin Bal çık-Erçin Arzu Aysan Nazl ı Salık Esma Erciyas Source Type: research

Exosomal Long Noncoding RNAs Serve as Biomarkers for Liver Disease
Turk J Gastroenterol. 2023 Jun 16. doi: 10.5152/tjg.2023.22741. Online ahead of print.ABSTRACTExosomes are tiny vesicles secreted by cells, with a diameter of 40-160 nm, which contain proteins, DNA, mRNA, long noncoding RNA, etc. Because of the low sensitivity and specificity of the conventional biomarkers for liver diseases, it is of utmost importance to discover novel, sensitive, specific, and non-invasive biomarkers. Exosomal long noncoding RNAs have been considered as potential diagnostic, prognostic, or predictive biomarkers in a wide range of liver pathologies. In this review, we discuss the recent progress on exosom...
Source: The Turkish Journal of Gastroenterology - June 16, 2023 Category: Gastroenterology Authors: Zixuan Yang Naping Tang Minhui Zheng Yan Chang Source Type: research

Parameters Predicting Microvascular Invasion and Poor Differentiation in Hepatocellular Carcinoma Patients with Normal Alpha-fetoprotein Level Before Liver Transplantation
CONCLUSIONS: In hepatocellular carcinoma patients with normal alpha-fetoprotein levels before liver transplantation, independent risk factors of the presence of microvascular invasion were maximum tumor diameter and number of nodules, and independent risk factors of poor differentiation were mean platelet volume and number of nodules. Furthermore, serum alpha-fetoprotein levels were still normal at time of recurrence in 53% of hepatocellular carcinoma patients whose alpha-fetoprotein levels were normal before liver transplantation but were elevated in 47% of the patients at recurrence time, despite having normal levels bef...
Source: The Turkish Journal of Gastroenterology - June 16, 2023 Category: Gastroenterology Authors: Burak M K ılcı Volkan İnce Brian I Carr Serta ç Usta Harika G Ba ğ Emine Şamdancı Burak I şık Sezai Y ılmaz Source Type: research