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Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research
