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Stroke after Radiotherapy for Head and Neck Cancer – What is the Risk?
Treating head and neck squamous cell carcinomas with radiotherapy has been shown to cause damage to the cerebrovasculature. This retrospective cohort study found that any exposure to radiation was associated with a 46% higher hazard of stroke, and with radiotherapy as the sole treatment modality, 70% increased risk of stroke compared to surgery alone. Implications of this research speak to the need for adequate follow-up and survivorship care among patients that were treated with RT.
Source: International Journal of Radiation Oncology * Biology * Physics - July 15, 2016 Category: Radiology Authors: Erin Arthurs, Timothy P. Hanna, Khaled Zaza, Yingwei Peng, Stephen F. Hall Source Type: research

Stroke After Radiation Therapy for Head and Neck Cancer: What Is the Risk?
A retrospective population-based cohort study was conducted to determine the risk of ischemic stroke with respect to time, associated with curative radiation therapy in head and neck squamous cell carcinomas (HNSCC).
Source: International Journal of Radiation Oncology * Biology * Physics - July 15, 2016 Category: Radiology Authors: Erin Arthurs, Timothy P. Hanna, Khaled Zaza, Yingwei Peng, Stephen F. Hall Tags: Clinical Investigation Source Type: research

Carotid Sparing Conformal Radiotherapy for Early Larynx Cancer
Parallel opposed lateral (POL) portals have been adopted as the mainstay radiation therapy technique for early-stage carcinoma of the glottis. Although the use of POL has been associated with excellent control rates and tolerability, the partial inclusion of carotid arteries (CAs) in the high dose regions of the fields has been shown to lead to an increased long-term risk of carotid stenosis and hemorrhagic stroke. Many researchers have proposed the utilization of three-dimension conformal therapy (3DCRT) or Intensity-modulated radiation therapy (IMRT) as viable carotid-sparing techniques via reductions to the mean and max...
Source: International Journal of Radiation Oncology * Biology * Physics - March 12, 2020 Category: Radiology Authors: N.S. Kalman, J. Laher, B. Zholendz Tags: Toxicity, Quality of Life, Survivorship, Costs of Care Source Type: research