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Cancer: Carcinoma

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A case of undifferentiated carcinoma of the bladder treated by combination therapy of surgery, local radiation, and immune checkpoint inhibitors
We present the case of an 81-year-old woman complaining of bladder irritation. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a bulky bladder tumor, which was diagnosed as cT4aN0M0. A transurethral resection of the bladder tumor revealed pT2 or higher urothelial carcinoma. The patient underwent total cystectomy with an ileal conduit diversion. Histological examination revealed a primary undifferentiated bladder carcinoma with a sarcoma component, pT3aN0M0. Postoperative adjuvant chemotherapy with gemcitabine plus carboplatin was administered. However, this regimen was discontinued after one course d...
Source: Nagoya Journal of Medical Science - December 22, 2022 Category: International Medicine & Public Health Authors: Wataru Nakane Yushi Naito Koya Morishita Kazuna Matsuo Shohei Ishida Yoshihisa Matsukawa Source Type: research