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The effect of intraoperative goal-directed fluid therapy combined with enhanced recovery after surgery program on postoperative complications in elderly patients undergoing thoracoscopic pulmonary resection: a prospective randomized controlled study
ConclusionsUnder ERAS program, there was no significant difference of AKI incidence between GDFT and RFT in elderly patients undergoing thoracoscopic pulmonary resection. But postoperative increase degree of serum creatinine was lower in GDFT group.Trial registrationRegistered at ClinicalTrials.gov, NCT04302467 on 26 February 2020.
Source: Perioperative Medicine - July 10, 2023 Category: Surgery Source Type: research

Comment on: Insurance-mandated weight management program completion before bariatric surgery provides no long-term clinical benefit
By 2030, 1 in 2 American adults is projected to have obesity and 1 in 4 clinically severe obesity. Obesity represents a serious public health issue because it is a major risk factor for many major, noncommunicable diseases, such as type 2 diabetes, coronary heart disease, stroke, chronic obstructive pulmonary disease, and cancer, and independently predicts overall mortality. The burden of obesity on medical spending is also significant, with $1861 in excess annual medical costs per adult with obesity and $3097 per adult with severe obesity —accounting for $173 billion annually in the United States [1].
Source: Surgery for Obesity and Related Diseases - November 15, 2022 Category: Surgery Authors: Hamlet Gasoyan, David B. Sarwer, Michael B. Rothberg Tags: Editorial comment Source Type: research

Precertification criteria for bariatric surgery should be based on evidence
By 2030, one in two American adults is projected to have obesity and one in four clinically severe obesity. Obesity represents a serious public health issue because it is a major risk factor for many major, non-communicable diseases, such as type 2 diabetes, coronary heart disease, stroke, chronic obstructive pulmonary disease, and cancer, and independently predicts overall mortality. The burden of obesity on medical spending is also significant, with $1,861 excess annual medical costs per adult with obesity and $3,097 per adult with severe obesity – accounting for $173 billion annually in the United States.
Source: Surgery for Obesity and Related Diseases - November 15, 2022 Category: Surgery Authors: Hamlet Gasoyan, David B. Sarwer, Michael B. Rothberg Source Type: research

Glucose variability and predicted cardiovascular risk after gastrectomy
ConclusionOur findings suggest that long-term follow-up and therapeutic strategies tailored to glycemic trends may be necessary for gastric cancer patients after gastrectomy, especially those with DM and those who have undergone TG, to prevent cardiovascular events.
Source: Surgery Today - October 30, 2022 Category: Surgery Source Type: research

Vascular adhesion protein-1 (VAP-1) in vascular inflammatory diseases
Vasa. 2022 Oct 6. doi: 10.1024/0301-1526/a001031. Online ahead of print.ABSTRACT Vascular adhesion protein-1 (VAP-1) also known as amino oxidase copper containing 3 (AOC3) is a pro-inflammatory and versatile molecule with adhesive and enzymatic properties. VAP-1 is a primary amine oxidase belonging to the semicarbazide-sensitive amine oxidase (SSAO) family, which catalyzes the oxidation of primary amines leading to the production of ammonium, formaldehyde, methylglyoxal, and hydrogen peroxide. VAP-1 is mainly expressed by endothelial cells, smooth muscle cells, adipocytes and pericytes. It is involved in a repertoire of bi...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 6, 2022 Category: Surgery Authors: Marianna Danielli Roisin Clare Thomas Lauren Marie Quinn Bee Kang Tan Source Type: research

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