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Quality-of-life, concerns, and treatment priorities in patients with cancer-related ischemic stroke: A prospective survey study
Comorbid cancer with stroke is a complex situation with multiple factors affecting quality of life (QoL). No specific questionnaire exists to assess current drivers of QoL and future concerns and priorities in patients with cancer-related stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 2, 2023 Category: Neurology Authors: Judy Dawod, Mohammad Hossein Abbasi, Babak B. Navi, Scott E. Kasner Source Type: research

Stroke as a cause of death in patients with cancer: a SEER-based study
Death from stroke is linked to cancer due to its pathogenesis and side effects of treatment. Despite this, guidelines regarding identifying cancer patients at the highest risk of mortality from stroke are unclear.
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2023 Category: Neurology Authors: Yousef Tarek Sonbol, Anas Elgenidy, Ahmed K. Awad, Ahmed O. Elmehrath, Hassan Kobeissi, Ahmed M. Afifi, Sherief Ghozy Source Type: research

Clinical features and prognostic factors in patients with cancer-associated multiple ischemic stroke: A retrospective observational study
Cancer causes coagulation abnormalities in arterial and venous systems.1,2 A highly active cancer is an established risk factor of ischemic stroke,3 and patients with cancer sometimes receive additional burden due to cancer-associated ischemic stroke (CAIS).4,5 Multiple cerebral infarctions involving various cerebrovascular territories in cryptogenic CAIS, referred to as “multiple CAIS” in this report, are of particular clinical interest since they lead to poor prognosis, with a median survival of at most a few months.
Source: Journal of Stroke and Cerebrovascular Diseases - October 21, 2022 Category: Neurology Authors: Jun Tanimura, Tomokiyo Yamamoto, Takao Hashimoto Source Type: research

Mutation of breast cancer susceptibility genes increases cerebral microbleeds: A pilot study
Growing evidence suggests breast cancer susceptibility gene (BRCA) mutations may augment cerebrovascular risk factors. With this influence in mind, we aimed to identify if BRCA mutations increased the prevalence of cerebral small vessel disease (CSVD).
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2022 Category: Neurology Authors: Brandon Pope, Zoe Wolcott, Marissa Castillo, Jacqueline Jin, Ka-Ho Wong, Adam de Havenon, Shadi Yaghi, Eric D. Goldstein Source Type: research

Understanding Coordinator Roles in Acute Stroke Care: A National Survey
Globally, stroke is a major contributor to death and disability.1 Evidence-based care in hospital after an acute stroke ensures improved survival and reduced disability, but care quality can vary.2,3 Clinical coordinators have an essential role in improving best-practice in trauma, cancer, diabetes, and heart failure conditions.4-7 Within stroke, coordinator roles are not new; in 1970, a study outlining the ‘Stroke Team’ model was published, which included a physician, nurse-coordinator and physical therapist.
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2021 Category: Neurology Authors: Tara Purvis, Sandy Middleton, Anne W. Alexandrov, Monique F. Kilkenny, Skye Coote, Sarah Kuhle, Dominique A. Cadilhac Source Type: research

Association Between Weight Loss and Activities of Daily Living in Obese and Overweight Patients after Stroke: A Cross-Sectional Study
Obesity is an important issue in global health care. Between 1975 and 2016, the proportion of obese individuals in the world nearly tripled. In fact, 39% of adults aged 18 years and older were overweight in 2016 and 13% were obese, using the traditional definition of overweight and obesity, namely, a body mass index (BMI)> 25 kg/m2 and> 30 kg/m2, respectively.1 Obesity is associated with a significant increase in mortality2,3 and the risk of many disorders, including metabolic and cardiovascular disease,4 cancer,5 infection,6 and physical limitations,7 as well as increasing healthcare costs.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2021 Category: Neurology Authors: Yoji Kokura, Shinta Nishioka Source Type: research

Prevalence and Predictors of Multivitamin Supplement Use After Stroke in Ghana
Multivitamin supplementation is widely practiced in high-income countries due to a popular belief of its health promotion and disease prevention benefits. Evidence for their purported efficacy has been mixed. Regarding the efficacy of multivitamins on prevention of cardiovascular disease, cancer, or all-cause mortality, some studies have shown no effect,1 –4 harmful effects,5,6 and beneficial effects.7,8 Three prospective studies have evaluated the effect of multivitamin use on stroke prevention with two showing negative outcomes3,5 and the third among 72,000 Japanese showing frequent use of multivitamins was associated ...
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2021 Category: Neurology Authors: Fred Stephen Sarfo, Bruce Ovbiagele Source Type: research

Effects of Neck Radiation on Result of Doppler Sonography of Carotid Arteries in Head and Neck Cancer Patients
The aim of this study was to assess the effects of neck radiation on the results of Doppler sonography of carotid arteries in head and neck cancer patients.
Source: Journal of Stroke and Cerebrovascular Diseases - January 15, 2021 Category: Neurology Authors: Ali Akhavan, Maryam Farghadani, Hamid Emami, Zahra Naderi Beni, Afsaneh Naderi Beni Source Type: research

Pathophysiology, Mechanism, and Outcome of Ischemic Stroke in Cancer Patients
The purpose of this study is to assess the risk factors, biomarkers of stroke, mechanism, and outcomes of cerebral infarction among cancerous diseases.
Source: Journal of Stroke and Cerebrovascular Diseases - September 17, 2020 Category: Neurology Authors: Mohamed Abdelsalam, Mohammad Abu-Hegazy, Hend Ahmed El-Hadaad, Hanan Wahba, Hossam Egila, Ahmed Esmael Source Type: research

Clinical Characteristics and Analysis of Lung Cancer- Associated Acute Ischemic Stroke
The incidence of lung cancer and acute ischemic stroke remains high in recent years, both of which occur mostly in people over 60 years old. In the present study, we aimed to further clarify the pathogenesis of lung cancer-associated acute ischemic stroke (LCA-AIS) by comparing and analyzing clinical characteristics of stroke patients with or without lung cancer.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Jing Zhang, Jingxia Zhao Source Type: research

Hematological Abnormalities and Malnutrition Mediate Pathway between Cancer and Outcomes in Ischemic Stroke Patients
The present study aimed to examine whether variables including D-dimer, high-sensitivity C-reactive protein (hsCRP), hemoglobin, platelet count, and nutritional status mediate the pathway between cancer and ischemic stroke outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: Yasufumi Gon, Daijiro Kabata, Tomohiro Kawano, Hideaki Kanki, Kenichi Todo, Tsutomu Sasaki, Ayumi Shintani, Hideki Mochizuki Source Type: research

Low Serum Eicosapentaenoic Acid Levels in Cryptogenic Stroke with Active Cancer
Since Armand Trousseau first described migratory superficial thrombophlebitis in 1865, patients with malignant cancer have been known to be in a hypercoagulable state and at risk for the development of cancer-associated thrombosis.1 Approximately 7% of cancer patients have symptomatic cerebrovascular diseases during the clinical course of cancer, and 15% have cerebrovascular lesions at autopsy.2 Previous studies have demonstrated that cancer patients with cryptogenic ischemic stroke often have high serum D-dimer levels and multiple vascular lesions and show cryptogenic stroke etiology, which seems to be due to a hypercoagulable state.
Source: Journal of Stroke and Cerebrovascular Diseases - May 14, 2020 Category: Neurology Authors: Tesseki Izumi, Hitoki Nanaura, Naohiko Iguchi, Maki Ozaki, Kazuma Sugie Source Type: research

Ability of the number of territories involved on dwi-mri to predict occult systemic malignancy in cryptogenic stroke patients
Lesions in multiple arterial territories is one of the typical features of malignancy patients with cryptogenic stroke. Hence, if patients with cryptogenic stroke display such feature, occult cancer could be predicted. The study aimed to analyze the predictive ability of the number of territories involved on DWI-MRI for occult systemic malignancy (OSM) in patients with cryptogenic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - April 29, 2020 Category: Neurology Authors: Linjia Guo, Lili Wang, Wenhong Liu Source Type: research

Risk of Ischemic Stroke and Major Bleeding in Patients With Atrial Fibrillation and Cancer
Background: Atrial fibrillation (AF) is an important risk factor for ischemic stroke. Cancer may increase the risk both of ischemic stroke and of bleeding. Less is known about risk of ischemic stroke and bleeding among cancer patients with AF, complicating the prevention of ischemic stroke in these patients. Methods: Register based cohort study comprising all Swedish patients hospitalized with a primary diagnosis of AF from July 1, 2005 until December 31, 2014. Patients with cancer diagnosis were compared to the rest of the cohort.
Source: Journal of Stroke and Cerebrovascular Diseases - December 26, 2019 Category: Neurology Authors: Sara Aspberg, Liyang Yu, Bruna Gigante, Karin E Smedby, Daniel E Singer Source Type: research

D-dimer and C-reactive Protein as Potential Biomarkers for Diagnosis of Trousseau's Syndrome in Patients with Cerebral Embolism
Differentiating stroke due to Trousseau's syndrome from other types of cerebral embolism is challenging, especially in patients with occult cancer. The current study aimed to determine predicting factors and biomarkers of stroke due to Trousseau's syndrome.
Source: Journal of Stroke and Cerebrovascular Diseases - December 3, 2019 Category: Neurology Authors: Michiko Tsushima, Norifumi Metoki, Joji Hagii, Shin Saito, Hiroshi Shiroto, Minoru Yasujima, Tomo Kato, Natsumi Kudo, Yuichi Toyama, Yoshikazu Yokono, Masashi Nozaka, Yosuke Kawamura, Masamichi Nakata, Hirofumi Tomita Source Type: research

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