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Risk of Ischemic and Hemorrhagic Strokes in Occult and Manifest Cancers Clinical Sciences
Conclusions—Cancer, occult and manifest, is associated with increased risks for stroke. The increased risk is linked mainly to cancers related to smoking.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Klaus Kaae Andersen, Tom Skyhoȷ Olsen Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

High Serum Level of Matrix Metalloproteinase-7 Is Associated With Increased Risk of Spontaneous Subarachnoid Hemorrhage Clinical Sciences
Conclusions—High serum level of MMP-7 was associated with increased risk of incident spontaneous SAH, independently of the main risk factors for SAH. High serum levels of MMP-2 and MMP-9 did not predict SAH risk.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Martin Soderholm, Gunilla Nordin Fredrikson, Jan Nilsson, Gunnar Engstrom Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Original Contributions Source Type: research

Prospective Study of Fasting Blood Glucose and Intracerebral Hemorrhagic Risk Clinical Sciences
The objective of the current study was to examine the potential impact of long-term fasting blood glucose concentration on subsequent risk of ICH.Methods—This prospective study included 96 110 participants of the Kailuan study, living in Kailuan community, Tangshan city, China, who were free of cardiovascular diseases and cancer at baseline (2006). Fasting blood glucose concentration was measured in 2006, 2008, 2010, and 2012. Updated cumulative average fasting blood glucose concentration was used as primary exposure of the current study. Incident ICH from 2006 to 2015 was confirmed by review of medical records.Results...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Cheng Jin, Guohong Li, Kathryn M. Rexrode, Mahmut E. Gurol, Xiaodong Yuan, Ying Hui, Chunyu Ruan, Anand Vaidya, Yanxiu Wang, Shouling Wu, Xiang Gao Tags: Cardiovascular Disease, Diabetes, Type 2, Epidemiology, Risk Factors, Intracranial Hemorrhage Original Contributions Source Type: research

Tumor Necrosis Factor Receptor 1 and 2 Are Associated With Risk of Intracerebral Hemorrhage Clinical Sciences
Conclusions—High plasma levels of TNFR1 and TNFR2 were associated with incident ICH, most clearly with ICH of nonlobar location. The results suggest that tumor necrosis factor–mediated inflammation could be associated with vascular changes preceding ICH.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Edith H. Svensson, Martin Soderholm, Kasim Abul–Kasim, Gunnar Engstrom Tags: Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Original Contributions Source Type: research

Daily Total Physical Activity and Incident Stroke Clinical Sciences
Conclusions—For Japanese people, moderate levels of total physical activity, particularly achieved by moderate-intensity activities, may be optimal for stroke prevention because excessive vigorous-intensity activities might not be beneficial or even disadvantageous for prevention of hemorrhagic stroke.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Yasuhiko Kubota, Hiroyasu Iso, Kazumasa Yamagishi, Norie Sawada, Shoichiro Tsugane Tags: Epidemiology, Exercise, Primary Prevention, Race and Ethnicity, Risk Factors Original Contributions Source Type: research

Adherence to a Healthy Nordic Diet and Risk of Stroke Clinical Sciences
Conclusions—Our findings suggest that a healthy Nordic diet may be recommended for the prevention of stroke.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Camilla Plambeck Hansen, Kim Overvad, Cecilie Kyro, Anȷa Olsen, Anne Tȷonneland, Soren Paaske Johnsen, Marianne Uhre Jakobsen, Christina Catherine Dahm Tags: Cardiovascular Disease, Diet and Nutrition, Epidemiology, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Association of Breakfast Intake With Incident Stroke and Coronary Heart Disease: The Japan Public Health Center-Based Study Clinical Sciences
Conclusions— The frequency of breakfast intake was inversely associated with the risk of stroke, especially cerebral hemorrhage in Japanese, suggesting that eating breakfast everyday may be beneficial for the prevention of stroke.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Kubota, Y., Iso, H., Sawada, N., Tsugane, S., The JPHC Study Group Tags: Cardiovascular Disease, Epidemiology, Primary Prevention, Risk Factors Clinical Sciences Source Type: research

Fibroblast Growth Factor 23 and Incidence of Subarachnoid Hemorrhage: Nested Case-Control Study Brief Reports
Conclusions— High FGF23 was associated with increased risk of incident SAH in subjects from the general population. Further studies should elucidate whether FGF23 is a causal risk factor for SAH, or could be used in risk prediction.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Soderholm, M., Engstrom, G. Tags: Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Epidemiology Brief Reports Source Type: research

Circulating Tissue Factor Levels and Risk of Stroke: Findings From the EPICOR Study Clinical Sciences
Conclusions— Our data provide evidence that elevated levels of circulating TF are potential risk factors for ischemic strokes.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Iacoviello, L., Di Castelnuovo, A., de Curtis, A., Agnoli, C., Frasca, G., Mattiello, A., Matullo, G., Ricceri, F., Sacerdote, C., Grioni, S., Tumino, R., Napoleone, E., Lorenzet, R., de Gaetano, G., Panico, S., Donati, M. B. Tags: Risk Factors, Coagulation, Acute Cerebral Hemorrhage Clinical Sciences Source Type: research

Multivitamin Use and Risk of Stroke Mortality: The Japan Collaborative Cohort Study Clinical Sciences
Conclusions— Multivitamin use, particularly frequent use, was associated with reduced risk of total and ischemic stroke mortality among Japanese people with lower intake of fruits and vegetables.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Dong, J.-Y., Iso, H., Kitamura, A., Tamakoshi, A., Japan Collaborative Cohort Study Group Tags: Primary prevention, Epidemiology Clinical Sciences Source Type: research

Dietary Cysteine and Other Amino Acids and Stroke Incidence in Women Clinical Sciences
Conclusions— These findings suggest that dietary cysteine intake may be inversely associated with risk of stroke. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01127698.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Larsson, S. C., Hakansson, N., Wolk, A. Tags: Epidemiology Clinical Sciences Source Type: research

Thrombolysis for Acute Ischemic Stroke in Patients With Cancer: A Population Study Brief Reports
Conclusions— Thrombolytic therapy for acute stroke in patients with cancer is not associated with increased risk of intracerebral hemorrhage or in-hospital mortality. However, careful consideration of the cancer subtype may help delineate the subset of patients with poor response to thrombolysis. Prospective confirmation is warranted.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Murthy, S. B., Karanth, S., Shah, S., Shastri, A., Rao, C. P. V., Bershad, E. M., Suarez, J. I. Tags: Emergency treatment of Stroke, Thrombolysis, Other Stroke Treatment - Surgical Brief Reports Source Type: research

Effect of Low-Dose Aspirin on Functional Outcome From Cerebral Vascular Events in Women Original Contributions
Conclusions— Results from this large randomized clinical trial provide evidence that 100 mg of aspirin every other day may reduce the risk of ischemic cerebral vascular events but does not have differential effects on functional outcomes from stroke.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Rist, P. M., Buring, J. E., Kase, C. S., Kurth, T. Tags: Acute Cerebral Infarction, Epidemiology Original Contributions Source Type: research

Physical Activity and Risk of Cerebrovascular Disease in the European Prospective Investigation Into Cancer and Nutrition-Spain Study Original Contributions
Conclusions— Recreational PA of moderate intensity was inversely associated with stroke incidence in women, whereas PA showed no effect on CVD risk in men. Increasing time dedicated to activities such as walking would be expected to help to reduce the stroke burden in women.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Huerta, J. M., Chirlaque, M.-D., Tormo, M.-J., Gavrila, D., Arriola, L., Moreno-Iribas, C., Amiano, P., Ardanaz, E., Barricarte, A., Dorronsoro, M., Egues, N., Larranaga, N., Molina-Montes, E., Quiros, J. R., Sanchez, M.-J., Gonzalez, C. A., Navarro, C. Tags: Obesity, Cerebrovascular disease/stroke, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Risk Factors for Stroke, Epidemiology Original Contributions Source Type: research