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Source: Neurology
Condition: Ischemic Stroke
Cancer: Cancer

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Total 29 results found since Jan 2013.

Prospective association between {beta}2-microglobulin levels and ischemic stroke risk among women
Conclusion: High levels of B2M were associated with an increased risk of ischemic stroke among women.
Source: Neurology - June 5, 2017 Category: Neurology Authors: Rist, P. M., Jimenez, M. C., Rexrode, K. M. Tags: All Cerebrovascular disease/Stroke, Case control studies, Risk factors in epidemiology ARTICLE Source Type: research

Probable REM sleep behavior disorder and risk of stroke: A prospective study
Conclusions: Presence of pRBD was associated with a higher risk of developing stroke, including both ischemic and hemorrhagic types. Future studies with clinically confirmed RBD and a longer follow-up would be appropriate to further investigate this association.
Source: Neurology - May 8, 2017 Category: Neurology Authors: Ma, C., Pavlova, M., Liu, Y., Liu, Y., Huangfu, C., Wu, S., Gao, X. Tags: All Cerebrovascular disease/Stroke, All Sleep Disorders, Cohort studies ARTICLE Source Type: research

Recurrent Stroke after Silent Brain Infarction in Patients with Primary Brain Tumors (S51.007)
Conclusions:The short-term risk of recurrent ischemic stroke in patients with PBTs was substantial and the risk was comparable whether the stroke was silent or symptomatic.Study Supported by: Babak Navi was supported by grants from the NINDS (K23NS091395) and the Florence Gould Endowment for Discovery in Stroke. Hooman Kamel was supported by grants from the NINDS (K23NS082367) and the Michael Goldberg Stroke Research Fund.Disclosure: Dr. Parikh has nothing to disclose. Dr. Burch has nothing to disclose. Dr. Kamel has received personal compensation for activities with Genentech as a speaker. Dr. Kamel has received personal ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Parikh, N., Burch, J., Kamel, H., DeAngelis, L., Navi, B. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke Prevention and Translation Source Type: research

Probable rapid eye movement sleep behavior disorder and risk of stroke: a prospective study (P4.302)
Conclusions:Presence of pRBD was associated with a higher risk of developing stroke, including both ischemic and hemorrhagic types. Future studies with clinically confirmed RBD and a longer follow-up would be appropriate to further investigate this association.Study Supported by: The National Institute of Neurological Disorders And Stroke at the National Institutes of Health (NINDS 5R21NS087235-02 to X.G.)Disclosure: Dr. Ma has nothing to disclose. Dr. Pavlova has received research support from Lundbeck and Biomobie Corporation. Dr. Liu has nothing to disclose. Dr. Liu has nothing to disclose. Dr. Huangfu has nothing to di...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ma, C., Pavlova, M., Liu, Y., Liu, Y., Huangfu, C., Wu, S., Gao, X. Tags: Neuroepidemiology: Cerebrovascular Disease I Source Type: research

The Vertebral Body Infarct Sign: A Case of Thoracic Spinal Cord Ischemic Stroke (P3.292)
Conclusions:While the vertebral body infarct sign is often recognized by neuro-radiologists, it is still relatively unknown to practicing neurologists. Early recognition of spinal cord infarct allows for timely evaluation for precipitating factors and initiation of secondary preventative therapies to decrease risk of further vascular events.Disclosure: Dr. Chan has nothing to disclose. Dr. Chan has nothing to disclose. Dr. Farooque has nothing to disclose. Dr. Nowak has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Chan, D., Chan, A., Farooque, P., Nowak, R. Tags: Cerebrovascular Disease Case Reports II Source Type: research

Excess mortality and hospitalized morbidity in newly treated epilepsy patients
Conclusions: Newly treated epilepsy patients bear excess mortality and hospitalization risks. They have higher risk of developing stroke, ischemic heart disease, and cancer. Treatment with EIAEDs was associated with increased overall morbidity.
Source: Neurology - August 14, 2016 Category: Neurology Authors: Chen, Z., Liew, D., Kwan, P. Tags: All Epilepsy/Seizures, Antiepileptic drugs ARTICLE Source Type: research

Lifetime direct costs of stroke for indigenous patients adjusted for comorbidities
Conclusions: The costs of stroke for indigenous people and patients with different comorbidities are substantial and an integrated prevention strategy is needed.
Source: Neurology - July 31, 2016 Category: Neurology Authors: Zhao, Y., Condon, J., Lawton, P., He, V., Cadilhac, D. A. Tags: Cost effectiveness/economic, All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

Glioproliferative Lesion of the Spinal Cord Derived from Intrathecal Administration of Stem Cells (P4.234)
CONCLUSIONS: Unregulated intrathecal SCT can cause devastating complications. This patient’s highly proliferative neoplasm developing from pluripotent stem cells supports the ideological shift to employ more differentiated cells in future SCT research.Disclosure: Dr. Saad has nothing to disclose. Dr. Miller has nothing to disclose. Dr. Cagney has nothing to disclose. Dr. Chavakula has nothing to disclose. Dr. Guleria has nothing to disclose. Dr. Aizer has nothing to disclose. Dr. Ligon has nothing to disclose. Dr. Chi has nothing to disclose. Dr. Berkowitz has received royalty payments from Clinical Pathophysiology M...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Saad, M., Miller, M., Cagney, D., Chavakula, V., Guleria, I., Aizer, A., Ligon, K., Chi, J., Berkowitz, A. Tags: Neuro-oncology: Neurologic Complications of Cancer Source Type: research

Pre-Mixing tPA: Moving Past Gestalt (P2.303)
Conclusions: While pre-mixing tPA does not incur financial risk as drug manufacturers replace unused vials without cost, stroke centers remain wary of wasting the drug. We believe succinct criteria can reduce avoidable tPA waste, allowing health care providers to remain fiscally responsible while ensuring AIS patients are treated as fast as possible.Disclosure: Dr. McCarthy has nothing to disclose. Dr. Caputo has nothing to disclose. Dr. Whaley has received personal compensation for activities with Clinical Data Management/Neurobase and Genentech. Dr. Fanale has received personal compensation for activities with Genentech,...
Source: Neurology - April 3, 2016 Category: Neurology Authors: McCarthy, K., Caputo, L., Whaley, M., Fanale, C., Bar-Or, D. Tags: Acute Therapy: IV t-PA Source Type: research

Reserve, Resilience and Recovery in Stroke: A Meta-Narrative Review (P3.199)
Conclusion: There is an urgent need to individualize outcomes in stroke systematically by implementing well validated concepts from various related fields to improve patient centered decision-making in acute stroke care.Disclosure: Dr. Dangayach has nothing to disclose. Dr. Grewal has nothing to disclose. Dr. Gordon has nothing to disclose. Dr. Mayer has received research support from Non-Invasive Medical Systems, Inc. and General Electric.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Dangayach, N., Grewal, H., Gordon, E., Mayer, S. Tags: Neurocritical Care: Clinical Science Source Type: research

Factors associated with delay in presentation to the hospital for young adults with ischemic stroke (P3.237)
Conclusions: A majority of young adults with ischemic stroke presented outside the time window for intravenous fibrinolysis. Diabetes, single status, and unemployed status were associated with delayed presentation. Disclosure: Dr. Leung has nothing to disclose. Dr. Louis R. Caplan has received personal compensation in an editorial capacity for JAMA Neurology.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Leung, L., Caplan, L. Tags: Stroke in the Young Source Type: research

A Case of Multiple Recurrent Ischemic Stroke in a Patient with Cholangiocarcinoma and Initiation of Anticoagulation Therapy for Secondary Stroke Prevention (P4.342)
CONCLUSIONS: Initiation of anticoagulation therapy and the optimal medications for secondary stroke prevention in cancer associated stroke remain controversial. Further randomized prospective studies are needed to establish treatment guidelines.Disclosure: Dr. Cheng has nothing to disclose. Dr. Then has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Cheng, J. Z., Then, R. Tags: Cerebrovascular Case Reports Source Type: research

Ischemic Stroke in Oncological Patients (P1.117)
Conclusions :In our series, serum DD levels, a marker of a hypercoagulable state, appear as a useful tool to identify patients with cryptogenic stroke and risk for underlying malignancy; while classical CRF failed to show differences between both groups (IS-C vs IS-nC). Interestingly, our patients showed a prevalence of a single vascular lesion subtype, against other previous series that reported a predominant pattern of multiple-lesions.Disclosure: Dr. Gatto has received personal compensation for activities with Tuteur, Bago, Novartis, and Glaxo-Smith Klein as a speaker and a scientific advisor. Dr. Persi has nothing to d...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Gatto, E., Persi, G., Lisei, D., Da Prat de Magahlaes, G., Rattagan, L., Lopez Vicchi, M., Parisi, V. L. Tags: Cerebrovascular Disease: Epidemiology Source Type: research

Neutrophils/Lymphocytes Ratio and Platelets/Lymphocytes Ratio and Its Relationship with Severity and Functional Prognosis in Patients with Acute Ischemic Stroke (P5.235)
CONCLUSIONS N/L ratio and P/L ratio at hospital admission have a positive correlation with the severity and functional prognosis of patients with Acute Ischemic Stroke. Due to its simple determination, affordable and safe, they could become severity and functional prognostic parameters in the initial evaluation of patients with Acute Ischemic Stroke in the future.Disclosure: Dr. Perez has nothing to disclose. Dr. Casas has nothing to disclose. Dr. Tourreilles has nothing to disclose. Dr. Gonzalez has nothing to disclose. Dr. Gimenez has nothing to disclose. Dr. Cabrera has nothing to disclose. Dr. Mattiazzi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Perez, A., Casas, S., Tourreilles, M., Gonzalez, C., Gimenez, J., Cabrera, L., Mattiazzi, M. Tags: Cerebrovascular Disease: Biomarkers Source Type: research

The effect of 24 hour post-intravenous alteplase CT head on management decisions: a single center experience (S47.004)
Conclusion: For 95[percnt] of asymptomatic patients, a 24 hour post-alteplase CT head had no clinical impact. Antithrombotic treatment was delayed by asymptomatic hemorrhage in 2/3 of patients, depriving them of early antiplatelet therapy that reduces the risk of stroke within the first 14 days (Lancet. 349:1569-81). With an estimated 30,000 doses of alteplase given in US, cost of routine CT screening is significant at $6.6 million per year (Jt Comm J Qual Patient Saf. 41:313-22), and there is increased risk of cancer from radiation of 1/10000 (Arch Intern Med. 169:2078-86). Further studies are needed to determine if benef...
Source: Neurology - February 7, 2016 Category: Neurology Authors: Sevilis, T., Morantes Gomez, L., Shah, N., Wang, M., Huang, D., Powers, W. Tags: IV-tPA and Endovascular Therapy Source Type: research