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Management: Food and Drug Administration (FDA)
Therapy: Antiviral Therapy
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Total 1 results found since Jan 2013.
Understanding Severe Acute Respiratory Syndrome Coronavirus 2 Replication to Design Efficient Drug Combination Therapies
Background: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its disease CO VID-19 has strongly encouraged the search for antiviral compounds. Most of the evaluated drugs against SARS-CoV-2 derive from drug repurposing of Food and Drug Administration-approved molecules. These drugs have as target three major processes: (1) early stages of virus-cell interaction, (2) viral proteases, and (3) the viral RNA-dependent RNA polymerase.Summary: This review focused on the basic principles of virology and pharmacology to understand the importance of early stages of virus-cell interaction as therap...
Source: Intervirology - October 23, 2020 Category: Virology Source Type: research
