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Specialty: Infectious Diseases
Source: Acta Virologica
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Total 701 results found since Jan 2013.
High resolution melting curve analysis for rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
Acta Virol. 2023;67(1):91-98. doi: 10.4149/av_2023_109.ABSTRACTSince the emergence of the original Wuhan SARS-CoV-2 strain, several new variants of the virus have emerged. Alpha, Beta, Gamma, Delta and the most recent Omicron variants have been introduced during this pandemic. Several methods including, but not restricted to, allele-specific PCR, ligation with rolling circle amplification and real-time PCR with allele-specific probes are able to detect mutations as low as a single nucleotide polymorphism. High-resolution melting curve analysis is ano-ther technique to assess any mutations in a nucleic acid chain. Confirmed...
Source: Acta Virologica - March 23, 2023 Category: Infectious Diseases Authors: Seyed Jalal Kiani Mehdi Ramshini Farah Bokharaei-Salim Tahereh Donyavi Babak Eshrati Majid Khoshmirsafa Saied Ghorbani Ahmad Tavakoli Seyed Hamidreza Monavari Zohreh Yousefi Ghalejoogh Mohammad Abbasi-Kolli Source Type: research
Structural and functional characterization of SARS-CoV-2 nucleocapsid protein mutations identified in Turkey by using in silico approaches
Acta Virol. 2023;67(1):59-68. doi: 10.4149/av_2023_106.ABSTRACTMissense mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus may cause changes in the structure of proteins. The nucleocapsid (N) protein is an important target for drugs and vaccines. The main purpose of this study is to detect missense mutations in the SARS-CoV-2 N protein and to reveal the effects of these mutations on protein structure by using in silico approaches. 161 missense mutations of the N protein were determined in 2286 SARS-CoV-2 genomes derived from the GISAID EpiCoV database in the Turkish population. Identified 1...
Source: Acta Virologica - March 23, 2023 Category: Infectious Diseases Authors: Betul Akcesme Burcin Erkal Zehra Yaren Donmez Source Type: research
High resolution melting curve analysis for rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
Acta Virol. 2023;67(1):91-98. doi: 10.4149/av_2023_109.ABSTRACTSince the emergence of the original Wuhan SARS-CoV-2 strain, several new variants of the virus have emerged. Alpha, Beta, Gamma, Delta and the most recent Omicron variants have been introduced during this pandemic. Several methods including, but not restricted to, allele-specific PCR, ligation with rolling circle amplification and real-time PCR with allele-specific probes are able to detect mutations as low as a single nucleotide polymorphism. High-resolution melting curve analysis is ano-ther technique to assess any mutations in a nucleic acid chain. Confirmed...
Source: Acta Virologica - March 23, 2023 Category: Infectious Diseases Authors: Seyed Jalal Kiani Mehdi Ramshini Farah Bokharaei-Salim Tahereh Donyavi Babak Eshrati Majid Khoshmirsafa Saied Ghorbani Ahmad Tavakoli Seyed Hamidreza Monavari Zohreh Yousefi Ghalejoogh Mohammad Abbasi-Kolli Source Type: research
Structural and functional characterization of SARS-CoV-2 nucleocapsid protein mutations identified in Turkey by using in silico approaches
Acta Virol. 2023;67(1):59-68. doi: 10.4149/av_2023_106.ABSTRACTMissense mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus may cause changes in the structure of proteins. The nucleocapsid (N) protein is an important target for drugs and vaccines. The main purpose of this study is to detect missense mutations in the SARS-CoV-2 N protein and to reveal the effects of these mutations on protein structure by using in silico approaches. 161 missense mutations of the N protein were determined in 2286 SARS-CoV-2 genomes derived from the GISAID EpiCoV database in the Turkish population. Identified 1...
Source: Acta Virologica - March 23, 2023 Category: Infectious Diseases Authors: Betul Akcesme Burcin Erkal Zehra Yaren Donmez Source Type: research
High resolution melting curve analysis for rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
Acta Virol. 2023;67(1):91-98. doi: 10.4149/av_2023_109.ABSTRACTSince the emergence of the original Wuhan SARS-CoV-2 strain, several new variants of the virus have emerged. Alpha, Beta, Gamma, Delta and the most recent Omicron variants have been introduced during this pandemic. Several methods including, but not restricted to, allele-specific PCR, ligation with rolling circle amplification and real-time PCR with allele-specific probes are able to detect mutations as low as a single nucleotide polymorphism. High-resolution melting curve analysis is ano-ther technique to assess any mutations in a nucleic acid chain. Confirmed...
Source: Acta Virologica - March 23, 2023 Category: Infectious Diseases Authors: Seyed Jalal Kiani Mehdi Ramshini Farah Bokharaei-Salim Tahereh Donyavi Babak Eshrati Majid Khoshmirsafa Saied Ghorbani Ahmad Tavakoli Seyed Hamidreza Monavari Zohreh Yousefi Ghalejoogh Mohammad Abbasi-Kolli Source Type: research
Structural and functional characterization of SARS-CoV-2 nucleocapsid protein mutations identified in Turkey by using in silico approaches
Acta Virol. 2023;67(1):59-68. doi: 10.4149/av_2023_106.ABSTRACTMissense mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus may cause changes in the structure of proteins. The nucleocapsid (N) protein is an important target for drugs and vaccines. The main purpose of this study is to detect missense mutations in the SARS-CoV-2 N protein and to reveal the effects of these mutations on protein structure by using in silico approaches. 161 missense mutations of the N protein were determined in 2286 SARS-CoV-2 genomes derived from the GISAID EpiCoV database in the Turkish population. Identified 1...
Source: Acta Virologica - March 23, 2023 Category: Infectious Diseases Authors: Betul Akcesme Burcin Erkal Zehra Yaren Donmez Source Type: research
High resolution melting curve analysis for rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
Acta Virol. 2023;67(1):91-98. doi: 10.4149/av_2023_109.ABSTRACTSince the emergence of the original Wuhan SARS-CoV-2 strain, several new variants of the virus have emerged. Alpha, Beta, Gamma, Delta and the most recent Omicron variants have been introduced during this pandemic. Several methods including, but not restricted to, allele-specific PCR, ligation with rolling circle amplification and real-time PCR with allele-specific probes are able to detect mutations as low as a single nucleotide polymorphism. High-resolution melting curve analysis is ano-ther technique to assess any mutations in a nucleic acid chain. Confirmed...
Source: Acta Virologica - March 23, 2023 Category: Infectious Diseases Authors: Seyed Jalal Kiani Mehdi Ramshini Farah Bokharaei-Salim Tahereh Donyavi Babak Eshrati Majid Khoshmirsafa Saied Ghorbani Ahmad Tavakoli Seyed Hamidreza Monavari Zohreh Yousefi Ghalejoogh Mohammad Abbasi-Kolli Source Type: research
Structural and functional characterization of SARS-CoV-2 nucleocapsid protein mutations identified in Turkey by using in silico approaches
Acta Virol. 2023;67(1):59-68. doi: 10.4149/av_2023_106.ABSTRACTMissense mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus may cause changes in the structure of proteins. The nucleocapsid (N) protein is an important target for drugs and vaccines. The main purpose of this study is to detect missense mutations in the SARS-CoV-2 N protein and to reveal the effects of these mutations on protein structure by using in silico approaches. 161 missense mutations of the N protein were determined in 2286 SARS-CoV-2 genomes derived from the GISAID EpiCoV database in the Turkish population. Identified 1...
Source: Acta Virologica - March 23, 2023 Category: Infectious Diseases Authors: Betul Akcesme Burcin Erkal Zehra Yaren Donmez Source Type: research
High resolution melting curve analysis for rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
Acta Virol. 2023;67(1):91-98. doi: 10.4149/av_2023_109.ABSTRACTSince the emergence of the original Wuhan SARS-CoV-2 strain, several new variants of the virus have emerged. Alpha, Beta, Gamma, Delta and the most recent Omicron variants have been introduced during this pandemic. Several methods including, but not restricted to, allele-specific PCR, ligation with rolling circle amplification and real-time PCR with allele-specific probes are able to detect mutations as low as a single nucleotide polymorphism. High-resolution melting curve analysis is ano-ther technique to assess any mutations in a nucleic acid chain. Confirmed...
Source: Acta Virologica - March 23, 2023 Category: Infectious Diseases Authors: Seyed Jalal Kiani Mehdi Ramshini Farah Bokharaei-Salim Tahereh Donyavi Babak Eshrati Majid Khoshmirsafa Saied Ghorbani Ahmad Tavakoli Seyed Hamidreza Monavari Zohreh Yousefi Ghalejoogh Mohammad Abbasi-Kolli Source Type: research
Structural and functional characterization of SARS-CoV-2 nucleocapsid protein mutations identified in Turkey by using in silico approaches
Acta Virol. 2023;67(1):59-68. doi: 10.4149/av_2023_106.ABSTRACTMissense mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus may cause changes in the structure of proteins. The nucleocapsid (N) protein is an important target for drugs and vaccines. The main purpose of this study is to detect missense mutations in the SARS-CoV-2 N protein and to reveal the effects of these mutations on protein structure by using in silico approaches. 161 missense mutations of the N protein were determined in 2286 SARS-CoV-2 genomes derived from the GISAID EpiCoV database in the Turkish population. Identified 1...
Source: Acta Virologica - March 23, 2023 Category: Infectious Diseases Authors: Betul Akcesme Burcin Erkal Zehra Yaren Donmez Source Type: research
High resolution melting curve analysis for rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
Acta Virol. 2023;67(1):91-98. doi: 10.4149/av_2023_109.ABSTRACTSince the emergence of the original Wuhan SARS-CoV-2 strain, several new variants of the virus have emerged. Alpha, Beta, Gamma, Delta and the most recent Omicron variants have been introduced during this pandemic. Several methods including, but not restricted to, allele-specific PCR, ligation with rolling circle amplification and real-time PCR with allele-specific probes are able to detect mutations as low as a single nucleotide polymorphism. High-resolution melting curve analysis is ano-ther technique to assess any mutations in a nucleic acid chain. Confirmed...
Source: Acta Virologica - March 23, 2023 Category: Infectious Diseases Authors: Seyed Jalal Kiani Mehdi Ramshini Farah Bokharaei-Salim Tahereh Donyavi Babak Eshrati Majid Khoshmirsafa Saied Ghorbani Ahmad Tavakoli Seyed Hamidreza Monavari Zohreh Yousefi Ghalejoogh Mohammad Abbasi-Kolli Source Type: research
Structural and functional characterization of SARS-CoV-2 nucleocapsid protein mutations identified in Turkey by using in silico approaches
Acta Virol. 2023;67(1):59-68. doi: 10.4149/av_2023_106.ABSTRACTMissense mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus may cause changes in the structure of proteins. The nucleocapsid (N) protein is an important target for drugs and vaccines. The main purpose of this study is to detect missense mutations in the SARS-CoV-2 N protein and to reveal the effects of these mutations on protein structure by using in silico approaches. 161 missense mutations of the N protein were determined in 2286 SARS-CoV-2 genomes derived from the GISAID EpiCoV database in the Turkish population. Identified 1...
Source: Acta Virologica - March 23, 2023 Category: Infectious Diseases Authors: Betul Akcesme Burcin Erkal Zehra Yaren Donmez Source Type: research
