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Condition: Pneumonia
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Total 13068 results found since Jan 2013.
Cysteamine-mediated blockade of the glycine cleavage system modulates epithelial cell inflammatory and innate immune responses to viral infection
Biochem Biophys Res Commun. 2023 Aug 15;677:168-181. doi: 10.1016/j.bbrc.2023.08.021. Online ahead of print.ABSTRACTTransient blockade of glycine decarboxylase (GLDC) can restrict de novo pyrimidine synthesis, which is a well-described strategy for enhancing the host interferon response to viral infection and a target pathway for some licenced anti-inflammatory therapies. The aminothiol, cysteamine, is produced endogenously during the metabolism of coenzyme A, and is currently being investigated in a clinical trial as an intervention in community acquired pneumonia resulting from viral (influenza and SARS-CoV-2) and bacter...
Source: Biochemical and Biophysical Research communications - August 19, 2023 Category: Biochemistry Authors: Douglas Fraser-Pitt Derry K Mercer Marie-Louise Francis David Toledo-Aparicio Daniel W Smith Deborah A O'Neil Source Type: research
Convalescent plasma from Norwegian blood donors to treat COVID-19
Tidsskr Nor Laegeforen. 2023 Jul 26;143(11). doi: 10.4045/tidsskr.22.0180. Print 2023 Aug 15.ABSTRACTBACKGROUND: At the start of the pandemic, the Norwegian Directorate of Health and Norwegian blood banks initiated the production of COVID-19 convalescent plasma within the framework of clinical studies. In this article we describe the blood donors who participated.MATERIAL AND METHOD: Blood donors who had recovered from COVID-19 were recruited to donate single donor plasma for the purpose of patient treatment. Data on the course of infection, leukocyte antibodies and antibody level against severe acute respiratory syndrome ...
Source: Tidsskrift for den Norske Laegeforening - August 17, 2023 Category: General Medicine Authors: Lise Sofie Haug Nissen-Meyer Tine Torsvik Steinsv åg Mona H øysæter Fenstad Ingvild Hausberg S ørvoll Marte Hvalryg Thomas Larsen Titze Karin Magnussen Gunn Kristoffersen Kathrine Margrethe Neuman Johnsen Abid Hussain Llohn Brita Hermundstad Lilja Syn Source Type: research
