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Research landscape on COVID-19 and liver dysfunction: A bibliometric analysis
CONCLUSION: This bibliometric study provides a comprehensive overview of liver-related publications in COVID-19 research over the past 3 years. This study highlights the significant contributions of high-income nations, particularly the United States, China, and Italy, to the production of liver-related scholarly literature in this field. Most of the articles focused on liver dysfunction in patients with COVID-19 and the implications of the virus for gastroenterologists and hepatologists.PMID:37545639 | PMC:PMC10401660 | DOI:10.3748/wjg.v29.i27.4356
Source: World Journal of Gastroenterology : WJG - August 7, 2023 Category: Gastroenterology Authors: Sa'ed H Zyoud Source Type: research

SARS-CoV-2 induced liver injury: Incidence, risk factors, impact on COVID-19 severity and prognosis in different population groups
World J Gastroenterol. 2023 Apr 28;29(16):2397-2432. doi: 10.3748/wjg.v29.i16.2397.ABSTRACTLiver is unlikely the key organ driving mortality in coronavirus disease 2019 (COVID-19) however, liver function tests (LFTs) abnormalities are widely observed mostly in moderate and severe cases. According to this review, the overall prevalence of abnormal LFTs in COVID-19 patients ranges from 2.5% to 96.8% worldwide. The geographical variability in the prevalence of underlying diseases is the determinant for the observed discrepancies between East and West. Multifactorial mechanisms are implicated in COVID-19-induced liver injury. ...
Source: World Journal of Gastroenterology : WJG - May 14, 2023 Category: Gastroenterology Authors: George D Liatsos Source Type: research

Interferon-lambda: New role in intestinal symptoms of COVID-19
World J Gastroenterol. 2023 Apr 7;29(13):1942-1954. doi: 10.3748/wjg.v29.i13.1942.ABSTRACTThe tremendous public health and economic impact of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a huge challenge globally. There is increasing evidence that SARS-CoV-2 induces intestinal infections. Type III interferon (IFN-λ) has an antiviral role in intestinal infection, with focused, long-lasting, and non-inflammatory characteristics. This review presents a summary of the structure of SARS-CoV-2, including its invasion and immune escape mechanisms. Emphasi...
Source: World Journal of Gastroenterology : WJG - May 8, 2023 Category: Gastroenterology Authors: Yi-Yang Pan Liu-Can Wang Feng Yang Min Yu Source Type: research

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