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Viruses, Vol. 15, Pages 693: Prolonged SARS-CoV-2 Infection and Organizing Pneumonia in a Patient with Follicular Lymphoma, Treated with Obinutuzumab & mdash;Challenging Recognition and Treatment
We present a case report of a patient with follicular lymphoma, treated with obinutuzumab, who was diagnosed with prolonged, ongoing SARS-CoV-2 infection and related organizing pneumonia. The recognition and the treatment were challenging which makes this case noteworthy. Antiviral therapy with several medications was administrated to our patient and their temporary, positive effect was observed. Moreover, high-dose intravenous immunoglobulin was applied, because slowly decreasing IgM and IgG levels were observed. The patient also received standard treatment of organizing pneumonia. We believe that such a complex approach ...
Source: Viruses - March 7, 2023 Category: Virology Authors: E. Łyżwa M. Sobiecka K. Lewandowska I. Siemion-Szcze śniak I. Bara ńska M. Klatt R. Langfort M. Szturmowicz W. Tomkowski Tags: Case Report Source Type: research

Viruses, Vol. 15, Pages 614: Rational Use of Monoclonal Antibodies as Therapeutic Treatment in an Oncologic Patient with Long COVID
This study highlights the Evusheld monoclonal antibodies’ efficacy, not only in prevention but also in successful therapy against prolonged COVID-19. Therefore, testing neutralizing monoclonal antibodies in vitro against SARS-CoV-2 mutants directly isolated from patients could provide useful information for the treatment of people affected by long COVID.
Source: Viruses - February 23, 2023 Category: Virology Authors: Maria Grazia Cusi Anna Maria Di Giacomo Gabriele Anichini Gianni Gori Savellini Chiara Terrosi Claudia Gandolfo Michele Maio Tags: Case Report Source Type: research

Viruses, Vol. 15, Pages 377: SARS-CoV-2 Genome Variations in Viral Shedding of an Immunocompromised Patient with Non-Hodgkin & rsquo;s Lymphoma
Conclusions. This report shows that the multiple mutations that occur in an immunocompromised patient with persistent COVID-19 could provide information regarding viral evolution and emergence of new SARS-CoV-2 variants.
Source: Viruses - January 28, 2023 Category: Virology Authors: Rodrigo Villase ñor-Echavarri Laura Gomez-Romero Alexandra Martin-Onraet Luis A. Herrera Marco A. Escobar-Arrazola Oscar A. Ramirez-Vega Coraz ón Barrientos-Flores Alfredo Mendoza-Vargas Alfredo Hidalgo-Miranda Diana Vilar-Compte Alberto Cedro-Tanda Tags: Case Report Source Type: research

Viruses, Vol. 13, Pages 2212: Single-Cell RNAseq Profiling of Human γδ T Lymphocytes in Virus-Related Cancers and COVID-19 Disease
ues Fournie The detailed characterization of human γδ T lymphocyte differentiation at the single-cell transcriptomic (scRNAseq) level in tumors and patients with coronavirus disease 2019 (COVID-19) requires both a reference differentiation trajectory of γδ T cells and a robust mapping method for additional γδ T lymphocytes. Here, we incepted such a method to characterize thousands of γδ T lymphocytes from (n = 95) patients with cancer or adult and pediatric COVID-19 disease. We found that cancer patients with human papillomavirus-positive head and neck squamous cell carcinoma and Epstein–Barr virus-positive H...
Source: Viruses - November 3, 2021 Category: Virology Authors: Juan Pablo Cerapio Marion Perrier Fr éderic Pont Marie Tosolini Camille Laurent St éphane Bertani Jean-Jacques Fournie Tags: Article Source Type: research

Viruses, Vol. 13, Pages 527: SARS-CoV-2 Infection and Antibody Response in a Symptomatic Cat from Italy with Intestinal B-Cell Lymphoma
Hofmann-Lehmann Since the coronavirus disease (COVID-19) pandemic was first identified in early 2020, rare cases of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in pet cats have been reported worldwide. Some reports of cats with SARS-CoV-2 showed self-limiting respiratory or gastrointestinal disease after suspected human-to-feline transmission via close contact with humans with SARS-CoV-2. In the present study, we investigated a cat with SARS-CoV-2 that was presented to a private animal clinic in Northern Italy in May 2020 in a weak clinical condition due to an underlying intestinal B-cell lym...
Source: Viruses - March 23, 2021 Category: Virology Authors: Julia Klaus Carlo Palizzotto Eric Zini Marina L. Meli Chiara Leo Herman Egberink Shan Zhao Regina Hofmann-Lehmann Tags: Case Report Source Type: research