No Heightened Risk of Suicide, Psychiatric Conditions With Acne Drug
(MedPage Today) -- Use of the acne medication isotretinoin (Accutane) was not associated with an increased risk of suicide or psychiatric conditions in a meta-analysis of 24 observational studies. The 1-year pooled absolute risk of completed suicide... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - December 1, 2023 Category: Psychiatry Source Type: news

Coronary Heart Disease by Age 45 Linked With Subsequent Dementia
(MedPage Today) -- Younger onset age of coronary heart disease was tied to higher risks of incident all-cause dementia, Alzheimer's disease, and vascular dementia, a large prospective cohort study in Great Britain showed. Each 10-year decrease... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 30, 2023 Category: Psychiatry Source Type: news

Coronary Heart Disease by Age 45 Linked With Later Dementia
(MedPage Today) -- Younger onset age of coronary heart disease was tied to higher risks of incident all-cause dementia, Alzheimer's disease, and vascular dementia, a large prospective cohort study in Great Britain showed. Each 10-year decrease... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 29, 2023 Category: Psychiatry Source Type: news

Increased Mortality Risk for Young Adults on High Doses of Antipsychotics
(MedPage Today) -- Antipsychotic medication-related deaths were rare among children, but young adults on higher doses had a significantly increased risk of death, according to a U.S. national retrospective cohort study of Medicaid patients. In... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 29, 2023 Category: Psychiatry Source Type: news

U.S. Suicides Hit Record High; FDA Reviews Schizophrenia Drug; Psychology of Misinfo
(MedPage Today) -- Provisional CDC estimates showed the suicide rate last year reached a record high since 1941 and was an age-adjusted 1% higher than in 2021. The FDA accepted Karuna Therapeutics' new drug application for its investigational... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 29, 2023 Category: Psychiatry Source Type: news

Safer to Hold Off on Intubating Comatose, Intoxicated Patients, Trial Finds
(MedPage Today) -- Holding off on intubation for patients in a coma with suspected acute poisoning safely got them home sooner in the NICO randomized trial. A conservative strategy of withholding intubation had a win ratio of 1.85 (95% CI 1.33... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 29, 2023 Category: Psychiatry Source Type: news

Cognitive Scores Improve With Personal Coaching
(MedPage Today) -- A personal coaching intervention led to modest cognitive improvements in older adults at high risk for dementia, the SMARRT pilot trial showed. After 2 years, the intervention group improved more on the cognitive primary outcome... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 27, 2023 Category: Psychiatry Source Type: news

Evolving Overdose Crisis Shakes Previously Effective Treatments
(MedPage Today) -- BURLINGTON, Vt. -- "You can't inject a horse tranquilizer and think nothing bad is gonna happen" to you, said Ty Sears, 33, a longtime drug user now in recovery. Sears was referring to xylazine, a sedative used for animal... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 25, 2023 Category: Psychiatry Source Type: news

Longer Use of ADHD Meds May Boost Heart Risk
(MedPage Today) -- Longer use of attention deficit-hyperactivity disorder (ADHD) medication was associated with an increased risk of cardiovascular disease, particularly hypertension and arterial disease, a nested case-control study from Sweden... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 22, 2023 Category: Psychiatry Source Type: news

Alzheimer's Drug Trials Should Report Effect Sizes, Researchers Say
(MedPage Today) -- Standard effect sizes are more meaningful outcomes in Alzheimer's disease drug trials than the widely used metric of percent slowing of decline, an analysis suggested. In recent trials of Alzheimer's anti-amyloid agents, effect... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 22, 2023 Category: Psychiatry Source Type: news

Positive KarXT Blood Pressure Data; ADHD Manufacturing Cover-Up? 'Profound Autism'
(MedPage Today) -- Karuna Therapeutics released reassuring phase Ib data mitigating blood pressure concerns with its investigational psychiatric drug KarXT; the novel agent is under review with the FDA for an indication in schizophrenia. A Massachusetts... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 22, 2023 Category: Psychiatry Source Type: news

Your SAD Patients May Not Understand Why They Feel Depressed
(MedPage Today) -- Two of my long-standing patients presented to me recently, both feeling depressed for the previous 2 weeks. The first, a woman in her late 60s, had been on heavy doses of antidepressants for years. She also had delayed sleep... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 21, 2023 Category: Psychiatry Source Type: news

Proteins Predict Signs of Alzheimer's Disease
(MedPage Today) -- Protein indicators of subclinical peripheral heath in plasma were linked with markers of Alzheimer's disease and neurodegeneration, cross-sectional proteomic analyses showed. Greater protein-based risk for cardiovascular disease... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 21, 2023 Category: Psychiatry Source Type: news

Shooting at Psych Hospital; Rosalynn Carter Dies; Millions in Medical Debt Canceled
(MedPage Today) -- Note that some links may require registration or subscription. A security guard was killed during a shooting at a New Hampshire psychiatric hospital; no patients were harmed and the suspect has been killed, according to authorities... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 20, 2023 Category: Psychiatry Source Type: news

Giving DHA to Preemies Doesn't Improve Behavioral Outcomes Later On
(MedPage Today) -- Administration of supplemental docosahexaenoic acid (DHA) to infants born at less than 29 weeks' gestation did not improve behavioral functioning at 5 years of age, a follow-up to a randomized trial showed. In more than 700... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - November 20, 2023 Category: Psychiatry Source Type: news