Antidepressants Linked to a Doubling of C difficile RiskAntidepressants Linked to a Doubling of C difficile Risk
Mirtazapine and fluoxetine appear to double the risk for Clostridium difficile infection, but other antidepressants show no link to an increased risk. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 7, 2013 Category: Consumer Health News Tags: Psychiatry News Source Type: news
HTA-SADD trial: Sertraline vs. mirtazapine vs. placebo for depression in dementia
Source: NIHR Health Technology Assessment programme
Area: News
This double-blind placebo-controlled RCT conducted at nine English old-age psychiatry units, examined the clinical effectiveness of sertraline and mirtazapine in reducing depression 13 weeks post randomisation compared with placebo. It involved 326 patients with probable or possible Alzheimer's disease (AD), depression (4+ weeks) and Cornell Scale for Depression in Dementia (CSDD) score of 8+. They were randomised to received these antidepressants (target dose 150 mg sertraline [n= 107] or 45 mg mirtazapine [n= 108] daily), or placebo (n= 111).
Ther...
Source: NeLM - Mental Health - March 7, 2013 Category: Psychiatry Source Type: news
