Application of the patient-reported outcome-based postoperative symptom management model in lung cancer: a multicenter randomized controlled trial protocol
Lung cancer is the most common cancer in China, with the highest mortality rate. Surgery is the primary treatment for early lung cancer. However, patients with lung cancer have a heavy burden of symptoms withi... (Source: Trials)
Source: Trials - February 17, 2024 Category: General Medicine Authors: Ying Liang, Pengyu Jing, Zhongping Gu, Lei Shang, Peng Ge, Yong Zhang, Lv Wang, Chun Qiu, Ximing Zhu and Zhijun Tan Tags: Study protocol Source Type: research
Exploring critical intervention features and trial processes in the evaluation of sensory integration therapy for autistic children
We evaluated the clinical and cost-effectiveness of manualised sensory integration therapy (SIT) for autistic children with sensory processing difficulties in a two-arm randomised controlled trial. Trial proce... (Source: Trials)
Source: Trials - February 17, 2024 Category: General Medicine Authors: Elizabeth Randell, Rachel McNamara, Monica Busse, Sue Delport, Rhys Williams-Thomas, Wakunyambo Maboshe, David Gillespie, Sarah Milosevic, Lucy Brookes-Howell, Melissa Wright, Richard P. Hastings, Anne Marie McKigney, Eleni Glarou and Alka Ahuja Tags: Research Source Type: research
Recurrences of advanced sessile and lateral spreading colorectal adenoma after endoscopic mucosal resection (EMR) thermal ablation versus no adjuvant therapy (RESPECT): a protocol of an international randomized controlled trial
Nowadays, large benign lateral spreading lesions (LSLs) and sessile polyps in the colorectum are mostly resected by endoscopic mucosal resection (EMR). A major drawback of EMR is the polyp recurrence rate of u... (Source: Trials)
Source: Trials - February 17, 2024 Category: General Medicine Authors: Gijs Kemper, Christian Gerges, Erik J. Schoon, Ramon-Michel Schreuder, Ruud R. W. Schrauwen, Ludger S. M. Epping, Torsten Beyna, Joost P. H. Drenth, Ufuk G ündug, Peter D. Siersema and Erwin J. M. van Geenen Tags: Study protocol Source Type: research
Recurrences of advanced sessile and lateral spreading colorectal adenoma after endoscopic mucosal resection (EMR) thermal ablation versus no adjuvant therapy (RESPECT): a protocol of an international randomized controlled trial
DiscussionThe RESPECT study will evaluate if STSC is effective in reducing recurrence rates after piecemeal EMR of large colorectal lesions in daily clinical practice performed by expert and non-expert endoscopists. Moreover, endoscopists will be allowed to use adjunctive techniques to remove remaining adenomatous tissue during the procedure. Finally, adenomatous polyp recurrence during follow-up will be defined by histologic identification.Trial registrationClinicalTrials.gov NCT05121805. Registered on 16 November 2021. Start recruitment: 17 March 2022. Planned completion of recruitment: 31 April 2025. (Source: Trials)
Source: Trials - February 17, 2024 Category: Research Source Type: clinical trials
Exploring critical intervention features and trial processes in the evaluation of sensory integration therapy for autistic children
ConclusionsThe process evaluation was highly valuable in identifying contextual factors that could impact the effectiveness of this individualised intervention. Rigorous evaluations of interventions for autistic children are important, especially given the limitations such as limited sample sizes and short-term follow-up as faced by previous research. One of the challenges lies in the variability of outcomes considered important by caregivers, as each autistic child faces unique challenges. It is crucial to consider the role of parents or other caregivers in facilitating access to these interventions and how this may impac...
Source: Trials - February 17, 2024 Category: Research Source Type: clinical trials
