Renal insufficiency due to an orthohantavirus infection in the north of the Netherlands
We describe a patient with an orthohantavirus infection in the north of the Netherlands. Orthohantavirus cases in the Netherlands are rare and most cases occur in the east of the Netherlands. Orthohantavirus infections should be included in the differential diagnosis in travellers and non-travellers, and patients from areas other than the east of the Netherlands if flu-like symptoms and acute renal insufficiency are present.PMID:33380537 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: L de Wolff S Vogels G I Andriesse I N Vlasveld Source Type: research

An uncommon side effect of thiamazole treatment in Graves' disease
Neth J Med. 2020 Dec;78(6):389-391.ABSTRACTThionamides (such as thiamazole/methimazole) are a common first line treatment for Graves' disease. Common side effects include rash, urticaria, and arthralgia. However, thionamide treatment has also been associated with a variety of auto-immune syndromes. Here, we describe a patient presenting with mild arthritis after starting thiamazole. Although severe presentation warrants acute withdrawal of the causative agent, our case suggests that milder forms can be successfully treated with anti-inflammatory drugs alone. Recognition of the syndrome is key to warrant timely and effectiv...
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: D van Moorsel R F Tummers-de Lind van Wijngaarden Source Type: research

Hypokalaemia and peripheral oedema in a Cushingoid patient with metastatic prostate cancer
This report describes a case of Cushing's syndrome that was probably caused by ectopic ACTH secretion by a LCNEC of the prostate.PMID:33380539 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: L M Schepers J M H Kisters C Wetzels G J Creemers Source Type: research

An impressive chest X-ray …
Neth J Med. 2020 Dec;78(6):392.NO ABSTRACTPMID:33380540 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: J Heidt E M van Keulen A E C A B Willemsen J M W van Haarst Source Type: research

Answer to Photoquiz An impressive chest X-ray …
Neth J Med. 2020 Dec;78(6):393-394.NO ABSTRACTPMID:33380541 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: J Heidt E M van Keulen A E C A B Willemsen J M W van Haarst Source Type: research

A polyposis syndrome
Neth J Med. 2020 Dec;78(6):395.NO ABSTRACTPMID:33380542 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: R J L F Loffeld K van der Hem I Ambrose Source Type: research

Answer to Photoquiz A polyposis syndrome
Neth J Med. 2020 Dec;78(6):395.NO ABSTRACTPMID:33380543 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: R J L F Loffeld K van der Hem I Ambrose Source Type: research

A fascinating liver abscess
Neth J Med. 2020 Dec;78(6):397.NO ABSTRACTPMID:33380544 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: C A J van Beers A-J van Tienhoven C Stijnis J Veenstra Source Type: research

Answer to Photoquiz A fascinating liver abscess
Neth J Med. 2020 Dec;78(6):398.NO ABSTRACTPMID:33380545 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: C A J van Beers A-J van Tienhoven C Stijnis J Veenstra Source Type: research

A bone disorder with skin lesions
Neth J Med. 2020 Dec;78(6):399.NO ABSTRACTPMID:33380546 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: L Hendrikx D F G J Wolthuis R J Hassing Source Type: research

Answer to Photoquiz A bone disorder with skin lesions
Neth J Med. 2020 Dec;78(6):400.NO ABSTRACTPMID:33380547 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: L Hendrikx D F G J Wolthuis R J Hassing Source Type: research

A diagnostic tool for self-poisoned patients: Analysis of gastric content and lavage fluids
In conclusion, we demonstrate that toxicological screening and quantification of drug levels in gastric content is possible and has potential as an adjunct in patient care, but limitations need to be addressed before implementation in clinical practice.PMID:33380548 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: L L G Sebek B C M de Winter C Bethlehem G Prins R Huisman J Alsma Source Type: research

Hypotonic polyuria: at the cross-roads of copeptin
Neth J Med. 2020 Dec;78(6):309-314.ABSTRACTThe aetiology of hypotonic polyuria, after excluding solute diuresis, is one of primary polydipsia, central, or nephrogenic diabetes insipidus. Theoretically, these disorders should be relatively easily distinguished based on history and the results of an indirect water deprivation test. Practically, however, there is a significant overlap in diagnostic evaluation, potentially leading to an erroneous diagnosis and deleterious management plan. The ability to measure a stimulated copeptin level, either with hypertonic saline or arginine infusion, has led to greater diagnostic accura...
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: A Gupta D Zimmerman Source Type: research

Severe acute respiratory infections surveillance for early signals in the community
CONCLUSION: This observational study demonstrates that routinely collected data can be used for describing trends of ARI in secondary care and may be suitable for near real-time SARI surveillance. In most seasons, the incidence peaks for ARI in secondary care preceded the peaks in primary care and crude mortality with a considerable time-lag. It would be of great value to add microbiological test results to the incidence data to better explain the difference in time-lag between these surveillance systems.PMID:33380528 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: S D Marbus G H Groeneveld L van Asten W van der Hoek M M A de Lange G A Donker P M Schneeberger J T van Dissel A B van Gageldonk-Lafeber Source Type: research

Implementation of 'Choosing Wisely Netherlands' for internal medicine
CONCLUSION: Four years after the introduction, only one-third of physicians and residents of internal medicine were aware of the Choosing Wisely Netherlands campaign. Nevertheless, most Choosing Wisely recommendations were implemented sufficiently in clinical practice. There is room for improvement, mainly in recommendations that need a multidisciplinary approach.PMID:33380529 (Source: The Netherlands Journal of Medicine)
Source: The Netherlands Journal of Medicine - December 31, 2020 Category: General Medicine Authors: B J Laan A A van de Woestijne H A H Kaasjager S E Geerlings Source Type: research