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Relationship between General Health, Lifestyle, Oral Health, and Periodontal Disease in Adults: A Large Cross-sectional Study in Japan.
Abstract The aim of this study was to investigate how general health, oral conditions, and lifestyle were associated with periodontal disease in adults, as clarifying this relationship may be useful in preventing periodontal disease. Medical checkups were conducted on individuals aged 40, 50, or 60 years. Data were obtained for analysis on a total of 36,110 patients (men, 12,784; women, 22,896). A stepwise logistic regression model was used to calculate the odds ratio (OR) for patients who were ≥code 3 according to the Community Periodontal Index (CPI). Approximately 40, 60, and 70% of men aged 40, 50, and 60 ye...
Source: The Bulletin of Tokyo Dental College - April 8, 2017 Category: Dentistry Authors: Kitagawa M, Kurahashi T, Matsukubo T Tags: Bull Tokyo Dent Coll Source Type: research

Swallowing Rehabilitation Affects Period of Hospitalization after Surgery for Tongue Cancer.
Abstract Functional rehabilitation has been reported to improve swallowing. The effect of the presence or absence of such rehabilitation has yet to be compared in oral cancer patients, however. The purpose of this study was to investigate its effect on correlations between the period of hospitalization and the period of tube feeding (from the day of surgery to termination of tube feeding) and period of oral nutrition (from termination of tube feeding to discharge). Body weight was also measured on admission and discharge and the difference calculated. A correlation was observed between period of hospitalization an...
Source: The Bulletin of Tokyo Dental College - April 8, 2017 Category: Dentistry Authors: Ohkubo M, Sugiyama T, Ohira M, Yamamoto M, Iguchi T, Shibahara T, Takano N, Ishida R Tags: Bull Tokyo Dent Coll Source Type: research

Efficiency of Closed Mastication of Gummy Evaluated with Gnatho-hexagraph.
In conclusion, the present results revealed that chewing efficiency improved with closed-lip mastication, indicating that instruction to seal the lips while eating is appropriate and necessary. PMID: 28381731 [PubMed - in process] (Source: The Bulletin of Tokyo Dental College)
Source: The Bulletin of Tokyo Dental College - April 8, 2017 Category: Dentistry Authors: Shima C, Motegi E, Horiuchi A, Ishii T, Nomura M, Nakao M, Sueishi K Tags: Bull Tokyo Dent Coll Source Type: research

Intentions and Factors Regarding Selection of Workplace by Postgraduate Dental Trainees after Clinical Training.
Abstract The purpose of the present study was to investigate the reasons governing selection of geographical location of workplace by postgraduate dental trainees. We believe that such data would aid in the development of measures aimed at reducing regional disparities in the number of dentists. A total of 10 dental colleges and faculties in Japan were invited to participate in the study. Anonymous, self-completed questionnaire surveys were given to 739 dentists at 13 clinical training facilities following training in 2012 and 2013; 713 responses were analyzed. The items surveyed included the local population in t...
Source: The Bulletin of Tokyo Dental College - April 8, 2017 Category: Dentistry Authors: Okawa Y, Hirata S, Nasu I, Hirata Y Tags: Bull Tokyo Dent Coll Source Type: research

Tooth Auto-transplantation: An Alternative Treatment.
In conclusion, although auto-transplantation is not very common in general dental practice, we believe that it offers a clinically and economically viable alternative to other complicated prosthetic and dental implant treatments. PMID: 28381733 [PubMed - in process] (Source: The Bulletin of Tokyo Dental College)
Source: The Bulletin of Tokyo Dental College - April 8, 2017 Category: Dentistry Authors: Ahmed Asif J, Yusuf Noorani T, Khursheed Alam M Tags: Bull Tokyo Dent Coll Source Type: research

Implant-supported Oral Rehabilitation in Child with Ectodermal Dysplasia - 4-year Follow-up.
Abstract Ectodermal dysplasia (ED) is an anomaly determined by genetic factors that alter ectodermal structures such as skin, hair, nails, glands, and teeth. Children affected by this condition require extensive, comprehensive, and multidisciplinary treatment. An 8-year-old female patient visited the Dentistry Clinic of the Federal University of Santa Catarina with the chief complaint of multiple missing teeth. The mother reported that the patient had ED. Clinical and radiographic examination revealed the congenital absence of several primary and permanent teeth and tooth germs. Subsequent oral rehabilitation comp...
Source: The Bulletin of Tokyo Dental College - April 8, 2017 Category: Dentistry Authors: Cezária Triches T, Ximenes M, Oliveira de Souza JG, Rodrigues Lopes Pereira Neto A, Cardoso AC, Bolan M Tags: Bull Tokyo Dent Coll Source Type: research

Status of Clinical Training at Tokyo Dental College and Subsequent Career Pathway - Focusing on Training Facilities and Programs.
In conclusion, training facility showed a markedly stronger influence on career pathway than training program. PMID: 28381735 [PubMed - in process] (Source: The Bulletin of Tokyo Dental College)
Source: The Bulletin of Tokyo Dental College - April 8, 2017 Category: Dentistry Authors: Hisanaga R, Takahashi T, Sato T, Yotsuya M, Shinya A, Miyake N Tags: Bull Tokyo Dent Coll Source Type: research

Relationship between Time from Full Pulpotomy to Definitive Diagnosis of Vertical Root Fracture and Patient Age.
Abstract The goal of this study was to investigate length of time between full pulpotomy and a definitive diagnosis of vertical root fracture (VRF), as well as the age at which this was made. The participants comprised 63 dental patients (40 men and 23 women) with a mean age of 65.7±10.4 years in whom a definitive diagnosis of VRF had been made between July 2013 and June 2015, and who had also undergone a full pulpotomy. The data on all these cases were obtained from 22 dental clinics belonging to a clinical study group. The mean duration between a full pulpotomy and a definitive diagnosis of VRF was 141.0±88.9 ...
Source: The Bulletin of Tokyo Dental College - April 8, 2017 Category: Dentistry Authors: Yoshino K, Ito K, Kuroda M, Sugihara N Tags: Bull Tokyo Dent Coll Source Type: research

Alveolar Growth in Japanese Infants : A Comparison between Now and 40 Years ago.
Abstract To investigate differences in alveolar growth during the primary dentition period among different age groups, dental arch width, length, and height were measured in 93 dental arch plaster models obtained from 4-year-olds born between 1968 and 1974, 88 from 5-year-olds born between 1968 and 1974 (70s group), 61 from 4-year-olds born between 2007 and 2009, and 56 from 5-year-olds born between 2006 and 2008 (2000s group). A comparison was also performed to determine whether there was any difference in change between 4 and 5 years of age. The results showed age- and sex-dependent differences in growth pattern...
Source: The Bulletin of Tokyo Dental College - April 8, 2017 Category: Dentistry Authors: Imai H, Makiguchi T, Arakawa A, Tashiro A, Yonezu T, Shintani S Tags: Bull Tokyo Dent Coll Source Type: research

Lymphangiogenesis and NOS Localization in Healing Process after Tooth Extraction in Akita Mouse.
In this study, lymphangiogenesis and expression of NO synthase (NOS) during the healing process after tooth extraction were investigated immunohistochemically in control (C57BL) and Akita mice as a diabetes model. Between 1, 4, and 10 days after extraction, expression of NOS, vascular endothelial growth factor-C (VEGF-C), VEGF receptor-3 (VEGFR-3), and von Willebrand factor was strongest during the granulation tissue phase. This suggests that severe inflammation triggers regulation of NOS and these other angiogenic and lymphangiogenic factors. During the callus phase, a few days after extraction, induced osteoblasts were p...
Source: The Bulletin of Tokyo Dental College - September 28, 2016 Category: Dentistry Authors: Takahashi S, Kikuchi R, Ambe K, Nakagawa T, Takada S, Ohno T, Watanabe H Tags: Bull Tokyo Dent Coll Source Type: research

Antimicrobial Susceptibility of Microorganisms Isolated from Periapical Periodontitis Lesions.
Abstract Periapical periodontitis usually results from microbial infection, with these microorganisms occasionally migrating to the root canal, which can lead to further, potentially life-threatening, complications. Here, the susceptibility of 27 bacterial strains to various antimicrobial agents was evaluated. These strains comprised 13 species; 16 of the strains were clinical isolates from periapical lesions. Each strain was inoculated onto blood agar plates containing one of the antimicrobial agents. The plates were incubated anaerobically at 37°C for 96 hr and the minimal inhibitory concentrations (MICs) deter...
Source: The Bulletin of Tokyo Dental College - September 28, 2016 Category: Dentistry Authors: Narita M, Shibahara T, Takano N, Fujii R, Okuda K, Ishihara K Tags: Bull Tokyo Dent Coll Source Type: research

Influence of Lifestyle Factors on Risk of Dental Caries among Children Living in Urban China.
Abstract The prevalence of dental caries has been decreasing among kindergarten children in Shanghai, China, over recent years, although it still remains at an unacceptably high level. The purpose of this study was to identify which factors were important in providing oral health guidance and achieving further improvement in the oral health status of kindergarten children in urban China. A survey was conducted on dental caries in 128 Japanese and 368 Chinese kindergarten children and a questionnaire given to their parents/guardians on each child's lifestyle and dietary habits from birth to the present. Correlation...
Source: The Bulletin of Tokyo Dental College - September 28, 2016 Category: Dentistry Authors: Kanemoto T, Imai H, Sakurai A, Dong H, Shi S, Yakushiji M, Shintani S Tags: Bull Tokyo Dent Coll Source Type: research

Relationship between Orthodontic Treatment Plan and Goslon Yardstick Assessment in Japanese Patients with Unilateral Cleft Lip and Palate: One-stage vs. Two-stage Palatoplasty.
Abstract The present study targeted patients with unilateral cleft lip and palate (UCLP) undergoing either one - (Wardill technique) or two-stage palatoplasty (Perko technique). Correlations between Goslon Yardstick scores and orthodontic appliances used and whether an osteotomy was performed were investigated. No differences were observed between the two types of palatoplasty in terms of Goslon Yardstick scores. A palatal expander and protraction facemask were used in Phase I of orthodontic treatment. The palatal expander was selected for most patients with UCLP in Phase I, regardless of the surgical technique us...
Source: The Bulletin of Tokyo Dental College - September 28, 2016 Category: Dentistry Authors: Ishii T, Sakamoto T, Ishikawa M, Yasumura T, Miyazaki H, Sueishi K Tags: Bull Tokyo Dent Coll Source Type: research

Propofol-remifentanil is More Effective than Propofol-fentanyl in Decreasing Intraoperative Blood Loss during Sagittal Split Ramus Osteotomy.
This study retrospectively compared blood loss during sagittal split ramus osteotomy in patients receiving propofol-remifentanil (R group) and those receiving propofol-fentanyl (F group). All patients underwent sagittal split ramus osteotomy under general anesthesia during the 3-year 4-month period between October 2007 and February 2011 in an operating room at Tokyo Dental College Suidobashi Hospital. Blood loss in the R group was significantly less than that in the F group. Mean arterial pressure and heart rate, measured at 20 and 15 min after tracheal intubation, respectively, were both lower in the R group. No marked ch...
Source: The Bulletin of Tokyo Dental College - September 28, 2016 Category: Dentistry Authors: Handa T, Onodera T, Honda Y, Koukita Y, Ichinohe T Tags: Bull Tokyo Dent Coll Source Type: research

Relationship between Obstructive Sleep Apnea and Self-assessed Oral Health Status: An Internet Survey.
Abstract The purpose of this study based on a cross-sectional internet survey was to investigate the relationship between risk of obstructive sleep apnea (OSA) and self-assessed oral health status. The participants, who comprised individuals registered with an online research company, were required to complete a self-reported questionnaire. Those answering in the affirmative to both of the following two questions were placed in the OSA-risk group, while those answering in the negative were assigned to the control group: 'Have other people noticed pauses in your breathing while you are sleeping?' and 'Do you feel e...
Source: The Bulletin of Tokyo Dental College - September 28, 2016 Category: Dentistry Authors: Suzuki S, Kojima Y, Takayanagi A, Yoshino K, Ishizuka Y, Satou R, Takahashi N, Tazaki M, Kamijo H, Sugihara N Tags: Bull Tokyo Dent Coll Source Type: research

Cutaneous Sinus Tract from Mandibular Second Molar with C-shaped Canal System and Improper Former Root Canal Treatment: A Case Report.
Abstract Here, we report the diagnosis and treatment of an extraoral cutaneous sinus tract originating in a mandibular second molar with a C-shaped root canal system. The patient was referred to our department by a dermatologist after a series of unsuccessful treatments, including antibiotics. Diffuse radiolucency on a preoperative radiograph revealed that earlier root canal treatment had been only partially successful. Consequently, we performed retreatment of the root canal comprising removal of the former restoration and gutta-percha, cleaning and shaping, and passive irrigation with sodium hypochlorite. The pa...
Source: The Bulletin of Tokyo Dental College - September 28, 2016 Category: Dentistry Authors: Gharechahi M, Dastmalchi P Tags: Bull Tokyo Dent Coll Source Type: research

Participation of Patient Community Members in Communication Classes for Dental Students at Tokyo Dental College.
Abstract In 2009, the Ministry of Education, Culture, Sports, Science and Technology launched its "Program for Promoting University Education and Student Support, Theme A: Program for Promoting University Education Reform". The ministry's stated aims were to 1) enhance student training centered on the needs of the individual patient; 2) improve their ability to make comprehensive diagnosis and treatment plans; and 3) instill high ethical standards and good communication skills. One of the main pillars of this project was to establish an educational organization aimed at encouraging public participation, the "Patie...
Source: The Bulletin of Tokyo Dental College - September 28, 2016 Category: Dentistry Authors: Takahashi N, Yamamoto H, Murakami S, Hirata S, Sugihara N, Mochizuki R, Takahashi T, Sato Y, Kawada E Tags: Bull Tokyo Dent Coll Source Type: research

Clear Cell Variant or Clear Cell Component?
PMID: 27320293 [PubMed - in process] (Source: The Bulletin of Tokyo Dental College)
Source: The Bulletin of Tokyo Dental College - June 22, 2016 Category: Dentistry Authors: Muramatsu T, Hashimoto S, Ide F Tags: Bull Tokyo Dent Coll Source Type: research

Tissue Reaction to Different Types of Calcium Hydroxide Paste in Rat.
Abstract The purpose of this study was to compare the biocompatibility of two types of calcium hydroxide paste in subcutaneous tissue in rat. Twenty-two Wistar rats were divided into 4 experimental (n=5 each) and one control (n=2) group. A polyethylene tube filled with either Dentsply or Sure-Paste was implanted in each rat in the experimental groups, while an empty polyethylene tube was used in the control group. After 15 or 60 days, the animals were sacrificed and histopathological examination carried out. Tissue reaction was assessed by inflammatory cell infiltration using a 4-point scoring system, ranging from...
Source: The Bulletin of Tokyo Dental College - June 22, 2016 Category: Dentistry Authors: Zarei M, Javidi M, Gharechahi M, Kateb M, Zare R, Kelagari ZS Tags: Bull Tokyo Dent Coll Source Type: research

Effect of Connector Design on Fracture Resistance in Zirconia-based Fixed Partial Dentures for Upper Anterior Region.
Abstract The purpose of this study was to investigate the influence of the cross-sectional form and area of the connector on fracture resistance in three-unit zirconia fixed partial denture (FPD) frameworks for the upper anterior region. Sixty FPD framework specimens were fabricated using the CAD/CAM system. The cross-sectional form (Type I, II, or III) and area (9.0, 7.0, 5.0, or 3.0 mm(2)) of the connectors differed. The specimens were fixed to a jig capable of applying a load axially to the abutment teeth at an angle of 135 degrees. Each specimen was subjected to fracture load measurements using a universal tes...
Source: The Bulletin of Tokyo Dental College - June 22, 2016 Category: Dentistry Authors: Ogino Y, Nomoto S, Sato T Tags: Bull Tokyo Dent Coll Source Type: research

Longitudinal Evaluation of Community Support Project to Improve Oral Function in Japanese Elderly.
Abstract Change in oral function was evaluated longitudinally in elderly persons participating in an Exercises for Healthy Oral Function program implemented as part of the Long-Term Care Prevention Project. The participants comprised high-risk and healthy persons aged 65 yr or over. A questionnaire was used to classify them into two groups ('every day or sometimes' or 'rarely') at the end of the study for a comparison of change in repetitive saliva swallowing test (RSST) scores and oral diadochokinesis between 3 time points: at before, at immediately after, and at 1 yr after completion of the program. The average ...
Source: The Bulletin of Tokyo Dental College - June 22, 2016 Category: Dentistry Authors: Sakayori T, Maki Y, Ohkubo M, Ishida R, Hirata S, Ishii T Tags: Bull Tokyo Dent Coll Source Type: research

Endodontic Treatment of Hypertaurodontic Mandibular Molar Using Reciprocating Single-file System: A Case Report.
Abstract Taurodontism is a developmental tooth disorder characterized by lack of constriction in the cementoenamel junction and consequent vertical stretch of the pulp chamber, accompanied by apical displacement of the pulpal floor. The endodontic treatment of teeth with this type of morpho-anatomical anomaly is challenging. The purpose of this article is to report the successful endodontic treatment of a hypertaurodontic mandibular molar using a reciprocating single-file system. PMID: 27320297 [PubMed - in process] (Source: The Bulletin of Tokyo Dental College)
Source: The Bulletin of Tokyo Dental College - June 22, 2016 Category: Dentistry Authors: C do Nascimento A, A F Marques A, C Sponchiado-Júnior E, F R Garcia L, M A de Carvalho F Tags: Bull Tokyo Dent Coll Source Type: research

Case of Suspected Sialodochitis Fibrinosa (Kussmaul's Disease).
Abstract Here we report a case of Kussmaul's disease, or sialodochitis fibrinosa. This rare disease is characterized by recurrent swelling of the salivary glands, which then discharge clots of fibrin into the oral cavity. An 80-year-old man with a history of allergic rhinitis visited our department with the chief complaint of pain in the bilateral parotid gland area on eating. An initial examination revealed mild swelling and tenderness in this region, and indurations could be felt around the bilateral parotid papillae. Pressure on the parotid glands induced discharge of gelatinous plugs from the parotid papillae....
Source: The Bulletin of Tokyo Dental College - June 22, 2016 Category: Dentistry Authors: Hayashi K, Onda T, Ohata H, Takano N, Shibahara T Tags: Bull Tokyo Dent Coll Source Type: research

Periodontal Regenerative Therapy in Patient with Chronic Periodontitis and Type 2 Diabetes Mellitus: A Case Report.
We report a case of generalized chronic periodontitis and type 2 diabetes mellitus requiring periodontal treatment including regenerative therapy. The patient was a 66-year-old man who presented with the chief complaint of gingival inflammation and mobile teeth in the molar region. He had been being treated for type 2 diabetes mellitus since 1999. His glycated hemoglobin (HbA1c) level was 7.8%. An initial examination revealed sites with a probing depth of ≥7 mm in the molar region, and radiography revealed angular bone defects in this area. Based on a clinical diagnosis of generalized chronic periodontitis, the patient u...
Source: The Bulletin of Tokyo Dental College - June 22, 2016 Category: Dentistry Authors: Seshima F, Nishina M, Namba T, Saito A Tags: Bull Tokyo Dent Coll Source Type: research

Adjunct Antimicrobial Therapy and Periodontal Surgery to Treat Generalized Aggressive Periodontitis: A Case Report.
Abstract Here we report a case of generalized aggressive periodontitis treated with periodontal therapy including adjunct antimicrobial therapy and periodontal surgery. The patient was a 22-year-old woman who presented with the chief complaint of gingival recession. Baseline examination revealed generalized plaque deposition and gingival inflammation. Thirty-nine percent of the sites had a probing depth (PD) of 4-6 mm and 2% a PD of ≥7 mm; 63% exhibited bleeding on probing (BOP). Radiographic examination revealed vertical bone loss in the molars and horizontal bone loss in other teeth. Microbiological examinatio...
Source: The Bulletin of Tokyo Dental College - June 22, 2016 Category: Dentistry Authors: Irokawa D, Makino-Oi A, Fujita T, Yamamoto S, Tomita S, Saito A Tags: Bull Tokyo Dent Coll Source Type: research

Comparison of Adhesive Resistance to Chewing Gum among Denture Base Acrylic Resin, Cobalt-Chromium Alloy, and Zirconia.
Abstract The purpose of this study was to compare the adhesiveness of chewing gum to acrylic resin, cobalt-chromium alloy, and zirconia. Test specimens were fabricated using acrylic resin (resin), cobalt-chromium alloy (Co-Cr), and Ceria stabilized tetragonal zirconia polycrystal-based nanostructured zirconia/alumina composite (zirconia). Specimens of each material were attached to the upper and lower terminals of a digital force gauge. The operator masticated chewing gum, wiped off any saliva, and placed the gum on the lower specimen. The gum was compressed to a thickness of 1 mm between the upper and lower speci...
Source: The Bulletin of Tokyo Dental College - March 12, 2016 Category: Dentistry Authors: Wada T, Takano T, Ueda T, Sakurai K Tags: Bull Tokyo Dent Coll Source Type: research

Effect of Cuff Pressure Elevation on Internal Diameter of Tracheal Tube in Simulated Trachea.
Abstract Application of nitrous oxide during anesthesia causes an increase in tracheal tube cuff pressure over time. The purpose of this study was to investigate the effect of an increase in cuff pressure on 3 types of tube (the Portex, Mallinckrodt, and Parker) commonly used for nasotracheal intubation. A cylindrical vessel was used to simulate a trachea. Cuff pressure was set at 0 cmH2O (R0) or 20 cmH2O (R20) at room temperature, or at 20 cmH2O (H20), 40 cmH2O (H40), 60 cmH2O (H60), or 80 cmH2O (H80) in 38°C hot water and pressure applied for 30 min. The value obtained at R0 was used as a reference (100%) and t...
Source: The Bulletin of Tokyo Dental College - March 12, 2016 Category: Dentistry Authors: Matsuki Y, Matsuura N, Ichinohe T Tags: Bull Tokyo Dent Coll Source Type: research

Tooth Loss in Problem-oriented, Irregular, and Regular Attenders at Dental Offices.
Abstract The aim of this retrospective study was to compare number of teeth lost among regular attenders (RAs), irregular attenders (IRAs), and problem-oriented attenders (POAs) at dental offices over a 10-yr observation period. Information on tooth loss was obtained from general practitioners. Patients were divided into 3 groups based on appointment adherence. A total of 1,886 teeth were lost in 1,400 patients. The mean number of teeth lost in men was 2.2±2.6 per patient over 10 yr in POAs, 1.2±1.7 in IRAs, and 1.5±1.5 in RAs. This number was significantly lower in IRAs (p = 0.011) or RAs (p=0.012) than in POA...
Source: The Bulletin of Tokyo Dental College - March 12, 2016 Category: Dentistry Authors: Yoshino K, Ito K, Kuroda M, Sugihara N Tags: Bull Tokyo Dent Coll Source Type: research

Application of 17% EDTA Enhances Diffusion of (45)Ca-labeled OH(-) and Ca(2+) in Primary Tooth Root Canal.
Abstract Proper cleaning of the root canal is key to the success of endodontic treatment as it allows more effective diffusion of medication throughout the dentinal tubules. The aim of this in vitro study was to investigate the efficacy of 17% ethylenediaminetetraacetic acid (EDTA) in enhancing diffusion of hydroxyl (OH(-)) and calcium ions (Ca(2+)) throughout the root canal in primary teeth. The canals of 25 primary tooth roots were cleaned with endodontic files and 1% sodium hypochlorite. Three groups (G) were then established: GI, in which final irrigation was performed with 1% sodium hypochlorite; GII, in whic...
Source: The Bulletin of Tokyo Dental College - March 12, 2016 Category: Dentistry Authors: Ximenes M, Cavalcanti Taguchi CM, Triches TC, Sartori N, Pereira Dias LA, de Araujo EB, Cardoso M Tags: Bull Tokyo Dent Coll Source Type: research

Post-treatment Stability in Angle Class III Cases.
Abstract The purpose of this study was to compare post-treatment stability in Angle Class III cases grouped by treatment modality into extraction, non-extraction, or surgical. Twenty-seven Angle Class III patients (9 men, 18 women) were selected from among the records of qualified retention cases treated at the Department of Orthodontics, Tokyo Dental College. The patients were divided into the following groups: Group 1, extraction (n=10); Group 2, non-extraction (n=9); and Group 3, surgery (n=8). Lateral cephalograms, panoramic X-rays, and study casts were obtained at baseline (T0), after active treatment (T1), a...
Source: The Bulletin of Tokyo Dental College - March 12, 2016 Category: Dentistry Authors: Yoshizumi J, Sueishi K Tags: Bull Tokyo Dent Coll Source Type: research

Endodontic Management of Maxillary First Molar with Five Root Canals, Including Two Distobuccal Root Canals: A Case Report.
Abstract Multiple canals in the root are part of the normal morphology of the tooth. A canal may sometimes be overlooked, however, and this may lead to failure of treatment. The first step in successful endodontic treatment, therefore, is gaining access to the pulp chamber and locating all the canals. In order to achieve this goal, practitioners need to be familiar with all possible variations in root canal morphology, and should thoroughly explore roots to ensure that all canals are identified, debrided, and obturated. Here, we report the diagnosis, treatment planning, and endodontic management of a maxillary fir...
Source: The Bulletin of Tokyo Dental College - March 12, 2016 Category: Dentistry Authors: Sinha DJ, Sinha AA, Prakash P, Jaiswal N Tags: Bull Tokyo Dent Coll Source Type: research

Prenatal Counseling on Prenatal Diagnosis of Cleft Lip and/or Cleft Palate at Tokyo Dental College Ichikawa General Hospital.
Abstract Remarkable technological advances have been made in the field of medicine in recent years, one result of which is that a prenatal diagnosis of cleft lip and/or cleft palate (CL/P) is now possible. In this situation, it is extremely important to provide the parents with mental care from the moment they are informed. Here, we describe cases of CL/P treated at our hospital and how such a diagnosis and prenatal counseling are handled. A survey was carried out on 4 cases seen at our department between April 2013 and March 2014. Patients are referred to our department from local or our own obstetrics clinics on...
Source: The Bulletin of Tokyo Dental College - March 12, 2016 Category: Dentistry Authors: Shibui T, Nomura T, Takano N, Katakura A, Nakano Y, Suga K, Narita M, Watanabe A, Muramatsu K, Takamatsu K Tags: Bull Tokyo Dent Coll Source Type: research

Radiopacity Measurement of Restorative Resins Using Film and Three Digital Systems for Comparison with ISO 4049: International Standard.
This study compared Ultra Speed Occlusal Film (USOF) and 3 digital systems in determining the radiopacity of 5 different restorative resins in terms of equivalents of aluminum thickness. Whether those digital systems could be used to determine whether radiopacity was in line with International Organization for Standardization (ISO) recommendations was also investigated. Disks of each of 5 restorative resins and an aluminum step wedge were exposed at 65 kVp and 10 mA on USOF and imaged with each digital system. Optical density on the film was measured with a transmission densitometer and the gray values on the digital image...
Source: The Bulletin of Tokyo Dental College - December 18, 2015 Category: Dentistry Authors: Kapila R, Matsuda Y, Araki K, Okano T, Nishikawa K, Sano T Tags: Bull Tokyo Dent Coll Source Type: research

Basic Finite Element Analysis of Para-periodontal Ligament in All-ceramic Zirconia Fixed Partial Denture.
Abstract The purpose of the present study was to investigate the validity of incorporating a para-periodontal ligament in the test mold used in a basic fracture test of a zirconia all-ceramic fixed partial denture (FPD). A simplified three-dimensional finite element analysis model was designed based on the three-unit FPD fracture test. Two types of model, one with and one without a para-periodontal ligament between the abutment and base mold, were fabricated. Microfocus CT of the missing first molar area in a dry human mandible was performed. A three-dimensional model was then fabricated based on the data obtained...
Source: The Bulletin of Tokyo Dental College - December 18, 2015 Category: Dentistry Authors: Nomoto S, Matsunaga S, Sato T, Yotsuya M, Abe S Tags: Bull Tokyo Dent Coll Source Type: research

Cytokeratin 13, Cytokeratin 17, Ki-67 and p53 Expression in Upper Layers of Epithelial Dysplasia Surrounding Tongue Squamous Cell Carcinoma.
Abstract Early detection of oral squamous cell carcinoma (OSCC) improves its prognosis and aids in selecting the appropriate treatment, which may also have a positive effect on quality of life. Early detection, therefore, is an important issue in the treatment of this disease. The purpose of this study was to investigate expression of cytokeratin 13 (CK13), CK17, Ki-67 and p53 as potential markers of tongue SCC. Five areas in 12 specimens were examined: the upper and lower layers of normal epithelium; those of dysplastic epithelial tissue surrounding the cancerous lesion; and the lesion itself. Strong expression o...
Source: The Bulletin of Tokyo Dental College - December 18, 2015 Category: Dentistry Authors: Matsuhira A, Noguchi S, Sato K, Tanaka Y, Yamamoto G, Mishima K, Katakura A Tags: Bull Tokyo Dent Coll Source Type: research

Metabolic Syndrome, Lifestyle, and Dental Caries in Japanese School Children.
Abstract The number of children with Metabolic Syndrome (MetS) has recently been increasing in Japan. Few studies have investigated the relationship between MetS and oral health. The aim of this study was to investigate the association between MetS, lifestyle, and oral health status in school children. Our goal is to utilize these results in health education aimed at preventing the onset of MetS in school children and adults. A total of 689 Japanese children (365 boys and 324 girls) aged between 10 and 13 years were examined and waist circumference (WC), ratio of WC to height, blood pressure, fasting blood sugar (...
Source: The Bulletin of Tokyo Dental College - December 18, 2015 Category: Dentistry Authors: Osawa H, Sugihara N, Ukiya T, Ishizuka Y, Birkhed D, Hasegawa M, Matsukubo T Tags: Bull Tokyo Dent Coll Source Type: research

Case of Severe Maxillary Protrusion Accompanied by Crowding and Scissor Bite.
Abstract This case involved a 30-year-old woman who visited our hospital with the main complaint of protrusion of the maxillary incisors and upper and lower lips. She had difficulty closing her lips, and a chin button was observed when the lips were closed. The skeletal pattern showed maxillary protrusion and mandibular retrusion, and the mandible showed severe high angle. Labial inclination of both the maxillary and mandibular incisors was found, as well as crowding. In addition, the maxillary left second molar showed buccal displacement, and scissor bite was evident in the left second molar region. The bilateral...
Source: The Bulletin of Tokyo Dental College - December 18, 2015 Category: Dentistry Authors: Katada H, Sueishi K Tags: Bull Tokyo Dent Coll Source Type: research

A Case of Simultaneous Ectopic Tooth Extraction and Removal of Migrated Dental Implant from Maxillary Sinus.
Abstract When a dental implant migrates to the maxillary sinus it should be extracted immediately as it may cause sinusitis or further migrate to one of the other paranasal sinuses. Although usually detected due to symptoms such as nasal obstruction, nasal discharge, and nasal bleeding, an ectopic tooth in the maxillary sinus can sometimes be revealed incidentally on radiographic examination. Here, we report a case of simultaneous extraction of a dental implant that had migrated to the maxillary sinus and removal of an ectopic tooth that had arisen in the same location. The patient was a 73-year-old man who had re...
Source: The Bulletin of Tokyo Dental College - December 18, 2015 Category: Dentistry Authors: Furuya Y, Norizuki Y, Yajima Y Tags: Bull Tokyo Dent Coll Source Type: research

Transient Receptor Potential Cation Channel Subfamily Vanilloid Member 3 is not Involved in Plasma Membrane Stretch-induced Intracellular Calcium Signaling in Merkel Cells.
Abstract Merkel cells (MCs), which form part of the MC-neurite complex, making contact with sensory afferents to drive mechanosensory transduction mechanisms, express transient receptor potential (TRP) cation channel subfamily vanilloid (V) members 1, 2, and 4, as well as ankyrin subfamily member 1. While these proteins are involved in sensing plasma membrane stretch, less is known about the functional properties of TRPV subfamily member 3 (TRPV3) during membrane stretch in MCs. The aim of this study was to determine whether TRPV3 channels were involved in mechanosensory activity by measuring intracellular free Ca...
Source: The Bulletin of Tokyo Dental College - December 18, 2015 Category: Dentistry Authors: Higashikawa A, Kojima Y, Sato M, Kimura M, Ogura K, Mochizuki H, Sase T, Shinya A, Kobune K, Furuya T, Sato T, Shibukawa Y, Tazaki M Tags: Bull Tokyo Dent Coll Source Type: research

Comparison of Dental Explorers and CPI-probes in Diagnosing Dental Caries.
Abstract The primary aim of the present study was to compare efficiency in detecting suspected caries requiring observation (CO) and decayed teeth (DT) between dental explorers and Community Periodontal Index (CPI)-probes in school dental examinations and evaluate the effect of their respective use on Decayed, Missing, Filled Teeth (DMFT) Index scores. A total of 126 elementary and high school students were examined. All the clinical findings were obtained by a pair of trained dentists examining each student at routine annual school dental examinations. A dental explorer or CPI-probe and dental mirror were used fo...
Source: The Bulletin of Tokyo Dental College - September 19, 2015 Category: Dentistry Authors: Ishizuka Y, Maki Y, Kagami N, Satou R, Sugihara N Tags: Bull Tokyo Dent Coll Source Type: research

Velocity of Canine Retraction in Angle Class I Treated with First Premolar Extraction: Effect of Facial Pattern.
Abstract Recently, new methods have been applied to increase velocity of tooth movement. A standard mean of tooth movement velocity remains to be established, however. Moreover, to our knowledge, no studies have investigated the effect of factors affecting this velocity. The aim of the present study was to investigate the effect of facial pattern on the mean velocity of canine retraction in selected cases of orthodontic treatment carried out at this hospital. A total of 112 patients with Angle Class I crowding treated with extraction of the bilateral maxillary and mandibular first premolars and a conventional edge...
Source: The Bulletin of Tokyo Dental College - September 19, 2015 Category: Dentistry Authors: Nakamura Y, Toyodome Y, Ishii T, Sakamoto T, Motegi E, Sueishi K Tags: Bull Tokyo Dent Coll Source Type: research

Treatment Capabilities of Postgraduate Dental Trainees at okyo Dental College Suidobashi Hospital Based on Dental Services Income.
Abstract As of fiscal year 2006, it became compulsory for all newly licensed dentists in Japan to undergo a year of practical training at one of the designated training facilities found throughout the country as part of their postgraduate programs. The goal of this training is for the trainees to acquire diagnostic and therapeutic skills. While officially trainees, they are nonetheless regarded as members of staff. Clinical training emphasizes improving both technical skills and theoretical knowledge. However, taking on such trainees is sometimes considered unprofitable, as work productivity is claimed to be low. ...
Source: The Bulletin of Tokyo Dental College - September 19, 2015 Category: Dentistry Authors: Sugito H, Hirata S, Sakayori T, Sato Y, Furusawa M, Yamashita S Tags: Bull Tokyo Dent Coll Source Type: research

Determinant Factors in Locating Main Occluding Area on Dental Arch.
Abstract The purpose of this study was to investigate which were the most important factors in determining the location of the main occluding area by comparing its site on the dental arch between patients treated with implant-supported prostheses and those with a shortened dental arch (SDA). Twenty-five patients with Eichner B1 occlusion were enrolled in the study. The molar region in each quadrant was always edentulous. Fifteen patients were treated with implant prostheses, while the remaining 10 patients had SDA. Each patient was instructed to clench a piece of temporary stopping in the occluding area that was p...
Source: The Bulletin of Tokyo Dental College - September 19, 2015 Category: Dentistry Authors: Kasahara T, Nakatsuka Y, Yamashita S, Mitsui T, Tanigawa Y, Kuroiwa A Tags: Bull Tokyo Dent Coll Source Type: research

Microscopic Endodontics in Infected Root Canal with Calcified Structure: A Case Report.
This report describes a case in which an operating microscope was used to facilitate the excision of a calcified structure from within a root canal at an early stage in the treatment of an infection. An 18-year-old man was referred to our clinic due to suspected chronic suppurative apical periodontitis of the right maxillary central incisor. Periapical radiography confirmed the presence of a radioopaque structure inside the root canal that was likely to pose an obstacle to endodontic treatment. After opening the pulp chamber, an operating microscope was used to directly confirm the presence of the calcified structure in th...
Source: The Bulletin of Tokyo Dental College - September 19, 2015 Category: Dentistry Authors: Suehara M, Sano Y, Sako R, Aida N, Fujii R, Muramatsu T, Furusawa M Tags: Bull Tokyo Dent Coll Source Type: research

Diagnosis and Endodontic Management of Fused Mandibular Second Molar and Paramolar with Concrescent Supernumerary Tooth Using Cone-beam CT and 3-D Printing Technology: A Case Report.
Abstract Supernumerary teeth in the molar area are classified as paramolars or distomolars based on location. They occur frequently in the maxilla, but only rarely in the mandible. These teeth are frequently fused with adjacent teeth. When this occurs, the pulp cavities may also be connected. This makes diagnosis and planning of endodontic treatment extremely difficult. Here we report a case of a mandibular second molar fused with a paramolar, necessitating dental pulp treatment. Intraoral and panoramic radiographs were obtained for an evaluation and diagnosis. Although the images revealed a supernumerary tooth-li...
Source: The Bulletin of Tokyo Dental College - September 19, 2015 Category: Dentistry Authors: Kato H, Kamio T Tags: Bull Tokyo Dent Coll Source Type: research

Additional Glucose-PTS Induction in Streptococcus mutans Mutant Deficient in Mannose- and Cellobiose-PTS.
Abstract Streptococcus mutans utilizes maltooligosaccharides, including maltose derived from human dietary starch. We recently reported that the glucose-phosphotransferase system (Glc-PTS) was also involved in the metabolism of glucose derived from intracellular maltooligosaccharides in S. mutans. The activity of the Glc-PTS was mediated by the mannose-(manLMN) and cellobiose-PTSs (celABRCD) in this organism. The purpose of this study was to identify which kind of glucose transporter was involved in this process. A celD, manLM, and glk triple mutant, cm6vU1, was constructed and its growth in maltose or glucose bro...
Source: The Bulletin of Tokyo Dental College - September 19, 2015 Category: Dentistry Authors: Sato Y, Okamoto-Shibayama K, Azuma T Tags: Bull Tokyo Dent Coll Source Type: research

Current State of Undergraduate Education in Oral Implantology in Japan.
Abstract An anonymous questionnaire-based survey was used to determine the current state of and issues involved in undergraduate education in oral implantology at Tokyo Dental College. The participants comprised 139 students who had received lectures on and practical training in oral implantology in 2013. The results indicate that the overall level of student comprehension was high for both lectures and practical training content; the level of difficulty was appropriate for practical training, but the amount of practice time given requires reconsideration. Over 80% of the students gave positive responses in their ...
Source: The Bulletin of Tokyo Dental College - June 20, 2015 Category: Dentistry Authors: Homma S, Sasaki H, Furuya Y, Ito T, Yajima Y Tags: Bull Tokyo Dent Coll Source Type: research

Influence of Prior Cervical Enlargement on Apical Cleaning Using Single File.
Abstract The goal of this study was to compare the apical cleaning capabilities of single files from 3 different rotary systems in the presence or absence of prior cervical preparation based on a histological analysis. A total of 84 human single-rooted mandibular permanent incisors were divided into 6 groups (14 canals each). Cleaning and shaping was performed under the following protocols: Group I, F2 ProTaper at working length; Group II, SX ProTaper and F2 ProTaper; Group III, size 25, .06 taper Mtwo at working length; Group IV, SX ProTaper and size 25, .06 taper Mtwo; Group V, size 25, .06 taper BR3 BioRace at ...
Source: The Bulletin of Tokyo Dental College - June 20, 2015 Category: Dentistry Authors: Piotto Leonardi D, Alfredo Schramm C, Fernando Giovanini A, Mariane Silveira C, Sens Fagundes Tomazinho F, Baratto-Filho F Tags: Bull Tokyo Dent Coll Source Type: research

Glucose-PTS Involvement in Maltose Metabolism by Streptococcus mutans.
Abstract Streptococcus mutans grows with starch-derived maltose in the presence of saliva. Maltose transported into the cells is mediated by the MalQ protein (4-alpha-glucanotransferase) to produce glucose and maltooligosaccharides. Glucose can be phosphorylated to glucose 6-phosphate, which can enter the glycolysis pathway. The MalQ enzyme is essential in the catabolism of maltose when it is the sole carbon source, suggesting the presence of a downstream glucokinase of the MalQ enzyme reaction. However, a glucokinase gene-inactivated mutant (glk mutant) grew with maltose as the sole carbon source, with no residua...
Source: The Bulletin of Tokyo Dental College - June 20, 2015 Category: Dentistry Authors: Sato Y, Okamoto-Shibayama K, Azuma T Tags: Bull Tokyo Dent Coll Source Type: research

Expression of Cytokeratin 14 and 19 in Process of Oral Carcinogenesis.
In this study, expression of CK14 and 19 was examined in human epithelial and dysplastic tissues. Surgical specimens from patients with clinically diagnosed oral leukoplakia or early cancer were stained with hematoxylin and eosin and classified into normal, low grade dysplasia (LGD), high grade dysplasia (HGD), or squamous cell carcinoma (SCC). The sections were examined by immunostaining and reverse transcription-polymerase chain reaction (RT-PCR) for CK14 and CK19. Expression and the results of RT-PCR for CK14 showed a decrease in the order of LGD, HGD, and SCC, whereas those of CK19 showed an increase in that order. The...
Source: The Bulletin of Tokyo Dental College - June 20, 2015 Category: Dentistry Authors: Yoshida K, Sato K, Tonogi M, Tanaka Y, Yamane GY, Katakura A Tags: Bull Tokyo Dent Coll Source Type: research