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Aberrant gene expression yet undiminished retinal ganglion cell genesis in iPSC-derived models of optic nerve hypoplasia
CONCLUSIONS: ONH genetic background was not associated with impaired RGC genesis but was associated with DEGs exhibiting disease contribution potential. This constitutes some of the first evidence of a genetic contribution to ONH.PMID:37807874 | DOI:10.1080/13816810.2023.2253902 (Source: Ophthalmic Genetics)
Source: Ophthalmic Genetics - October 9, 2023 Category: Opthalmology Authors: Jennifer G Aparicio Hanno Hopp Narine Harutyunyan Carly Stewart David Cobrinik Mark Borchert Source Type: research