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Beyond molecular tumor heterogeneity: protein synthesis takes control
Beyond molecular tumor heterogeneity: protein synthesis takes control, Published online: 21 February 2018; doi:10.1038/s41388-018-0152-0Beyond molecular tumor heterogeneity: protein synthesis takes control (Source: Oncogene)
Source: Oncogene - February 21, 2018 Category: Cancer & Oncology Authors: Santiago Ramon y Cajal Josep Castellvi Stefan H ümmer Vicente Peg Jerry Pelletier Nahum Sonenberg Source Type: research

The path to metastatic mouse models of colorectal cancer
The path to metastatic mouse models of colorectal cancer, Published online: 21 February 2018; doi:10.1038/s41388-018-0155-xThe path to metastatic mouse models of colorectal cancer (Source: Oncogene)
Source: Oncogene - February 21, 2018 Category: Cancer & Oncology Authors: Gabriele Romano Sharmeen Chagani Lawrence N. Kwong Source Type: research

Elevated mitochondrial SLC25A29 in cancer modulates metabolic status by increasing mitochondria-derived nitric oxide
Elevated mitochondrial SLC25A29 in cancer modulates metabolic status by increasing mitochondria-derived nitric oxide, Published online: 20 February 2018; doi:10.1038/s41388-018-0139-xElevated mitochondrial SLC25A29 in cancer modulates metabolic status by increasing mitochondria-derived nitric oxide (Source: Oncogene)
Source: Oncogene - February 20, 2018 Category: Cancer & Oncology Authors: Huiyuan Zhang Qinyi Wang Junzhong Gu Le Yin Shenghui Liang Lida Wu Hao Xu Chao Zhao Yuchun Gu Source Type: research

The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia
The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia, Published online: 20 February 2018; doi:10.1038/s41388-018-0131-5The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia (Source: Oncogene)
Source: Oncogene - February 20, 2018 Category: Cancer & Oncology Authors: Hao Wang Ling Bei Chirag A. Shah Weiqi Huang Leonidas C. Platanias Elizabeth A. Eklund Source Type: research

Novel synthetic bisindolylmaleimide alkaloids inhibit STAT3 activation by binding to the SH2 domain and suppress breast xenograft tumor growth
Novel synthetic bisindolylmaleimide alkaloids inhibit STAT3 activation by binding to the SH2 domain and suppress breast xenograft tumor growth, Published online: 19 February 2018; doi:10.1038/s41388-017-0076-0Novel synthetic bisindolylmaleimide alkaloids inhibit STAT3 activation by binding to the SH2 domain and suppress breast xenograft tumor growth (Source: Oncogene)
Source: Oncogene - February 19, 2018 Category: Cancer & Oncology Authors: Xia Li Hongguang Ma Lin Li Yifan Chen Xiao Sun Zizheng Dong Jing-Yuan Liu Weiming Zhu Jian-Ting Zhang Source Type: research

Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C
Heterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C, Published online: 16 February 2018; doi:10.1038/s41388-017-0105-zHeterogeneity and mutation in KRAS and associated oncogenes: evaluating the potential for the evolution of resistance to targeting of KRAS G12C (Source: Oncogene)
Source: Oncogene - February 16, 2018 Category: Cancer & Oncology Authors: Vincent L. Cannataro Stephen G. Gaffney Carly Stender Zi-Ming Zhao Mark Philips Andrew E. Greenstein Jeffrey P. Townsend Source Type: research

Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer
Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer, Published online: 16 February 2018; doi:10.1038/s41388-018-0132-4Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer (Source: Oncogene)
Source: Oncogene - February 16, 2018 Category: Cancer & Oncology Authors: Sherona R. Sirkisoon Richard L. Carpenter Tadas Rimkus Ashley Anderson Alexandria Harrison Allison M. Lange Guangxu Jin Kounosuke Watabe Hui-Wen Lo Source Type: research

Arresting of miR-186 and releasing of H19 by DDX43 facilitate tumorigenesis and CML progression
Arresting of miR-186 and releasing of H19 by DDX43 facilitate tumorigenesis and CML progression, Published online: 16 February 2018; doi:10.1038/s41388-018-0146-yArresting of miR-186 and releasing of H19 by DDX43 facilitate tumorigenesis and CML progression (Source: Oncogene)
Source: Oncogene - February 16, 2018 Category: Cancer & Oncology Authors: J. Lin J.-C. Ma J. Yang J.-Y. Yin X.-X. Chen H. Guo X.-M. Wen T.-J. Zhang W. Qian J. Qian Z.-Q. Deng Source Type: research

The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization
The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization, Published online: 16 February 2018; doi:10.1038/s41388-018-0134-2The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization (Source: Oncogene)
Source: Oncogene - February 16, 2018 Category: Cancer & Oncology Authors: Lei Li Tongzheng Liu Yunhui Li Chenming Wu Kuntian Luo Yujiao Yin Yuping Chen Somaira Nowsheen Jinhuan Wu Zhenkun Lou Jian Yuan Source Type: research

Snail regulates BMP and TGFβ pathways to control the differentiation status of glioma-initiating cells
Snail regulates BMP and TGFβ pathways to control the differentiation status of glioma-initiating cellsSnail regulates BMP and TGFβ pathways to control the differentiation status of glioma-initiating cells, Published online: 16 February 2018; doi:10.1038/s41388-018-0136-0Snail regulates BMP and TGFβ pathways to control the differentiation status of glioma-initiating cells (Source: Oncogene)
Source: Oncogene - February 16, 2018 Category: Cancer & Oncology Authors: Laia Caja Kalliopi Tzavlaki Mahsa S. Dadras E-Jean Tan Gad Hatem Naga P. Maturi Anita Mor én Lotta Wik Yukihide Watanabe Katia Savary Masood Kamali-Moghaddan Lene Uhrbom Carl-Henrik Heldin Aristidis Moustakas Source Type: research

Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-κB/IL-6/STAT3 axis
Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-κB/IL-6/STAT3 axisTumor cell-intrinsic Tim-3 promotes liver cancer via NF-κB/IL-6/STAT3 axis, Published online: 16 February 2018; doi:10.1038/s41388-018-0140-4Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-κB/IL-6/STAT3 axis (Source: Oncogene)
Source: Oncogene - February 16, 2018 Category: Cancer & Oncology Authors: Hualin Zhang Yang Song Huimin Yang Zhiyan Liu Lifen Gao Xiaohong Liang Chunhong Ma Source Type: research

Metabolic features of cancer stem cells: the emerging role of lipid metabolism
Metabolic features of cancer stem cells: the emerging role of lipid metabolism, Published online: 15 February 2018; doi:10.1038/s41388-018-0141-3Metabolic features of cancer stem cells: the emerging role of lipid metabolism (Source: Oncogene)
Source: Oncogene - February 14, 2018 Category: Cancer & Oncology Authors: Rita Mancini Alessia Noto Maria Elena Pisanu Claudia De Vitis Marcello Maugeri-Sacc à Gennaro Ciliberto Source Type: research

Differential role of FL-BID and t-BID during verotoxin-1-induced apoptosis in Burkitt’s lymphoma cells
Differential role of FL-BID and t-BID during verotoxin-1-induced apoptosis in Burkitt’s lymphoma cellsDifferential role of FL-BID and t-BID during verotoxin-1-induced apoptosis in Burkitt’s lymphoma cells, Published online: 14 February 2018; doi:10.1038/s41388-018-0123-5Differential role of FL-BID and t-BID during verotoxin-1-induced apoptosis in Burkitt’s lymphoma cells (Source: Oncogene)
Source: Oncogene - February 14, 2018 Category: Cancer & Oncology Authors: Justine Debernardi Emilie Hollville Marc Lipinski Jo ëlle Wiels Aude Robert Source Type: research

BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis
BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis, Published online: 14 February 2018; doi:10.1038/s41388-018-0127-1BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis (Source: Oncogene)
Source: Oncogene - February 14, 2018 Category: Cancer & Oncology Authors: Tyler J. Lahusen Seung-Jin Kim Kai Miao Zebin Huang Xiaoling Xu Chu-Xia Deng Source Type: research

Non-canonical activation of hedgehog in prostate cancer cells mediated by the interaction of transcriptionally active androgen receptor proteins with Gli3
Non-canonical activation of hedgehog in prostate cancer cells mediated by the interaction of transcriptionally active androgen receptor proteins with Gli3, Published online: 12 February 2018; doi:10.1038/s41388-017-0098-7Non-canonical activation of hedgehog in prostate cancer cells mediated by the interaction of transcriptionally active androgen receptor proteins with Gli3 (Source: Oncogene)
Source: Oncogene - February 12, 2018 Category: Cancer & Oncology Authors: Na Li Sarah Truong Mannan Nouri Jackson Moore Nader Al Nakouzi Amy Anne Lubik Ralph Buttyan Source Type: research

Nucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis
Nucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis, Published online: 12 February 2018; doi:10.1038/s41388-017-0121-zNucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis (Source: Oncogene)
Source: Oncogene - February 12, 2018 Category: Cancer & Oncology Authors: Mikael S. Lindstr öm Deana Jurada Sladana Bursac Ines Orsolic Jiri Bartek Sinisa Volarevic Source Type: research

The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity
The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity, Published online: 12 February 2018; doi:10.1038/s41388-017-0092-0The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity (Source: Oncogene)
Source: Oncogene - February 12, 2018 Category: Cancer & Oncology Authors: Andrew B. Fielding Matthew Concannon Sarah Darling Emma V. Rusilowicz-Jones Joseph J. Sacco Ian A. Prior Michael J. Clague Sylvie Urb é Judy M. Coulson Source Type: research

p53 isoforms regulate premature aging in human cells
p53 isoforms regulate premature aging in human cells, Published online: 12 February 2018; doi:10.1038/s41388-017-0101-3p53 isoforms regulate premature aging in human cells (Source: Oncogene)
Source: Oncogene - February 12, 2018 Category: Cancer & Oncology Authors: Natalia von Muhlinen Izumi Horikawa Fatima Alam Kazunobu Isogaya Delphine Lissa Borek Vojtesek David P Lane Curtis C. Harris Source Type: research

SRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-κB-CD47 axis
SRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-κB-CD47 axisSRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-κB-CD47 axis, Published online: 12 February 2018; doi:10.1038/s41388-017-0119-6SRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-κB-CD47 axis (Source: Oncogene)
Source: Oncogene - February 12, 2018 Category: Cancer & Oncology Authors: Fei Liu Miao Dai Qinyang Xu Xiaolu Zhu Yang Zhou Shuheng Jiang Yahui Wang Zhihong Ai Li Ma Yanli Zhang Lipeng Hu Qin Yang Jun Li Shujie Zhao Zhigang Zhang Yincheng Teng Source Type: research

Decitibine improve the efficiency of anti-PD-1 therapy via activating the response to IFN/PD-L1 signal of lung cancer cells
Decitibine improve the efficiency of anti-PD-1 therapy via activating the response to IFN/PD-L1 signal of lung cancer cells, Published online: 09 February 2018; doi:10.1038/s41388-018-0125-3Decitibine improve the efficiency of anti-PD-1 therapy via activating the response to IFN/PD-L1 signal of lung cancer cells (Source: Oncogene)
Source: Oncogene - February 8, 2018 Category: Cancer & Oncology Authors: Qi Lai Haiyong Wang Angui Li Yinhui Xu Liang Tang Qiang Chen Chunfang Zhang Yang Gao Jianfei Song Zhenzong Du Source Type: research

Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis
Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis, Published online: 05 February 2018; doi:10.1038/s41388-017-0093-zAdipocyte-induced CD36 expression drives ovarian cancer progression and metastasis (Source: Oncogene)
Source: Oncogene - February 5, 2018 Category: Cancer & Oncology Authors: Andras Ladanyi Abir Mukherjee Hilary A. Kenny Alyssa Johnson Anirban K. Mitra Sinju Sundaresan Kristin M. Nieman Gloria Pascual Salvador Aznar Benitah Anthony Montag S. Diane Yamada Nada A. Abumrad Ernst Lengyel Source Type: research

Ibrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner
Ibrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner, Published online: 05 February 2018; doi:10.1038/s41388-017-0079-xIbrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner (Source: Oncogene)
Source: Oncogene - February 5, 2018 Category: Cancer & Oncology Authors: Femina Rauf Fernanda Festa Jin G. Park Mitchell Magee Seron Eaton Capria Rinaldi Carlos Morales Betanzos Laura Gonzalez-Malerva Joshua LaBaer Source Type: research

PHLPP1 mediates melanoma metastasis suppression through repressing AKT2 activation
PHLPP1 mediates melanoma metastasis suppression through repressing AKT2 activation, Published online: 02 February 2018; doi:10.1038/s41388-017-0061-7PHLPP1 mediates melanoma metastasis suppression through repressing AKT2 activation (Source: Oncogene)
Source: Oncogene - February 2, 2018 Category: Cancer & Oncology Authors: Yanlin Yu Meng Dai Andrew Lu Ellen Yu Glenn Merlino Source Type: research

The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim
The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim, Published online: 02 February 2018; doi:10.1038/s41388-017-0112-0The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim (Source: Oncogene)
Source: Oncogene - February 2, 2018 Category: Cancer & Oncology Authors: Lazaro E. Aira Elodie Villa Pascal Colosetti Parvati Gamas Laurie Signetti Sandrine Obba Emma Proics Fabien Gautier B éatrice Bailly-Maitre Arnaud Jacquel Guillaume Robert Fr édéric Luciano Philippe P. Juin Jean-Ehrland Ricci Patrick Auberger Sandrine Source Type: research

Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer
Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer, Published online: 02 February 2018; doi:10.1038/s41388-017-0108-9Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer (Source: Oncogene)
Source: Oncogene - February 2, 2018 Category: Cancer & Oncology Authors: Özge Saatci Simone Borgoni Özge Akbulut Selvi Durmu ş Umar Raza Erol Ey üpoğlu Can Alkan Aytekin Akyol Özgür Kütük Stefan Wiemann Özgür Şahin Source Type: research

Novel identification of STAT1 as a crucial mediator of ETV6-NTRK3-induced tumorigenesis
Novel identification of STAT1 as a crucial mediator of ETV6-NTRK3-induced tumorigenesis, Published online: 02 February 2018; doi:10.1038/s41388-017-0102-2Novel identification of STAT1 as a crucial mediator of ETV6-NTRK3-induced tumorigenesis (Source: Oncogene)
Source: Oncogene - February 2, 2018 Category: Cancer & Oncology Authors: Jinah Park Junil Kim Bora Park Kyung-Min Yang Eun Jin Sun Cristina E. Tognon Poul H. Sorensen Seong-Jin Kim Source Type: research

Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-β-dependent and -independent mechanisms
Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-β-dependent and -independent mechanismsDecreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-β-dependent and -independent mechanisms, Published online: 02 February 2018; doi:10.1038/s41388-017-0084-0Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-β-dependent and -independent mechanisms (Source: Oncogene)
Source: Oncogene - February 2, 2018 Category: Cancer & Oncology Authors: Jun Nishida Kohei Miyazono Shogo Ehata Source Type: research

Clofarabine inhibits Ewing sarcoma growth through a novel molecular mechanism involving direct binding to CD99
Clofarabine inhibits Ewing sarcoma growth through a novel molecular mechanism involving direct binding to CD99, Published online: 31 January 2018; doi:10.1038/s41388-017-0080-4Clofarabine inhibits Ewing sarcoma growth through a novel molecular mechanism involving direct binding to CD99 (Source: Oncogene)
Source: Oncogene - January 31, 2018 Category: Cancer & Oncology Authors: Haydar Çelik Marika Sciandra Bess Flashner Elif Gelmez Neslihan Kayrakl ıoğlu David V. Allegakoen Jeff R. Petro Erin J. Conn Sarah Hour Jenny Han Lalehan Oktay Purushottam B. Tiwari Mutlu Hayran Brent T. Harris Maria Cristina Manara Jeffrey A. Toretsky Source Type: research

TRIM25 enhances cell growth and cell survival by modulating p53 signals via interaction with G3BP2 in prostate cancer
TRIM25 enhances cell growth and cell survival by modulating p53 signals via interaction with G3BP2 in prostate cancer, Published online: 30 January 2018; doi:10.1038/s41388-017-0095-xTRIM25 enhances cell growth and cell survival by modulating p53 signals via interaction with G3BP2 in prostate cancer (Source: Oncogene)
Source: Oncogene - January 30, 2018 Category: Cancer & Oncology Authors: Ken-ichi Takayama Takashi Suzuki Tomoaki Tanaka Tetsuya Fujimura Satoru Takahashi Tomohiko Urano Kazuhiro Ikeda Satoshi Inoue Source Type: research

MUC1-C activates polycomb repressive complexes and downregulates tumor suppressor genes in human cancer cells
MUC1-C activates polycomb repressive complexes and downregulates tumor suppressor genes in human cancer cells, Published online: 30 January 2018; doi:10.1038/s41388-017-0096-9MUC1-C activates polycomb repressive complexes and downregulates tumor suppressor genes in human cancer cells (Source: Oncogene)
Source: Oncogene - January 30, 2018 Category: Cancer & Oncology Authors: Hasan Rajabi Masayuki Hiraki Donald Kufe Source Type: research

c-Src activity is differentially required by cancer cell motility modes
c-Src activity is differentially required by cancer cell motility modes, Published online: 30 January 2018; doi:10.1038/s41388-017-0071-5c-Src activity is differentially required by cancer cell motility modes (Source: Oncogene)
Source: Oncogene - January 30, 2018 Category: Cancer & Oncology Authors: Jeremy S. Logue Alexander X. Cartagena-Rivera Richard S. Chadwick Source Type: research

PAX8 activates a p53-p21-dependent pro-proliferative effect in high grade serous ovarian carcinoma
PAX8 activates a p53-p21-dependent pro-proliferative effect in high grade serous ovarian carcinoma, Published online: 30 January 2018; doi:10.1038/s41388-017-0040-zPAX8 activates a p53-p21-dependent pro-proliferative effect in high grade serous ovarian carcinoma (Source: Oncogene)
Source: Oncogene - January 30, 2018 Category: Cancer & Oncology Authors: Dima Ghannam-Shahbari Eyal Jacob Reli Rachel Kakun Tanya Wasserman Lina Korsensky Ofir Sternfeld Juliana Kagan Debora Rosa Bublik Sarit Aviel-Ronen Keren Levanon Edmond Sabo Sarit Larisch Moshe Oren Dov Hershkovitz Ruth Perets Source Type: research

Aggressive serous epithelial ovarian cancer is potentially propagated by EpCAM+CD45+ phenotype
Aggressive serous epithelial ovarian cancer is potentially propagated by EpCAM+CD45+ phenotype, Published online: 30 January 2018; doi:10.1038/s41388-017-0106-yAggressive serous epithelial ovarian cancer is potentially propagated by EpCAM+CD45+ phenotype (Source: Oncogene)
Source: Oncogene - January 30, 2018 Category: Cancer & Oncology Authors: Md Zahid Akhter Surender K Sharawat Vikash Kumar Veena Kochat Zaffar Equbal Mallika Ramakrishnan Umesh Kumar Sandeep Mathur Lalit Kumar Asok Mukhopadhyay Source Type: research

CHTM1, a novel metabolic marker deregulated in human malignancies
CHTM1, a novel metabolic marker deregulated in human malignancies, Published online: 26 January 2018; doi:10.1038/s41388-017-0051-9CHTM1, a novel metabolic marker deregulated in human malignancies (Source: Oncogene)
Source: Oncogene - January 26, 2018 Category: Cancer & Oncology Authors: Mansi Babbar Ying Huang Jie An Steve K. Landas M. Saeed Sheikh Source Type: research

A functional interplay between Δ133p53 and ΔNp63 in promoting glycolytic metabolism to fuel cancer cell proliferation
A functional interplay between Δ133p53 and ΔNp63 in promoting glycolytic metabolism to fuel cancer cell proliferationA functional interplay between Δ133p53 and ΔNp63 in promoting glycolytic metabolism to fuel cancer cell proliferation, Published online: 26 January 2018; doi:10.1038/s41388-017-0117-8A functional interplay between Δ133p53 and ΔNp63 in promoting glycolytic metabolism to fuel cancer cell proliferation (Source: Oncogene)
Source: Oncogene - January 26, 2018 Category: Cancer & Oncology Authors: Lu Gong Xiao Pan Chuan-Bian Lim Anna de Polo John B. Little Zhi-Min Yuan Source Type: research

The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53
The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53, Published online: 25 January 2018; doi:10.1038/s41388-017-0022-1The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53 (Source: Oncogene)
Source: Oncogene - January 25, 2018 Category: Cancer & Oncology Authors: Anette Szczepny Kirstyn Carey Lisa McKenzie W. Samantha N. Jayasekara Fernando Rossello Alvaro Gonzalez-Rajal Andrew S. McCaw Dean Popovski Die Wang Anthony J. Sadler Annabelle Mahar Prudence A. Russell Gavin Wright Rachael A. McCloy Daniel J. Garama Dani Source Type: research

PTEN loss in the fallopian tube induces hyperplasia and ovarian tumor formation
PTEN loss in the fallopian tube induces hyperplasia and ovarian tumor formation, Published online: 25 January 2018; doi:10.1038/s41388-017-0097-8PTEN loss in the fallopian tube induces hyperplasia and ovarian tumor formation (Source: Oncogene)
Source: Oncogene - January 25, 2018 Category: Cancer & Oncology Authors: Angela Russo Austin A. Czarnecki Matthew Dean Dimple A. Modi Daniel D. Lantvit Laura Hardy Seth Baligod David A. Davis Jian-Jun Wei Joanna E. Burdette Source Type: research

Wild-type and mutated IDH1/2 enzymes and therapy responses
Wild-type and mutated IDH1/2 enzymes and therapy responses, Published online: 25 January 2018; doi:10.1038/s41388-017-0077-zWild-type and mutated IDH1/2 enzymes and therapy responses (Source: Oncogene)
Source: Oncogene - January 25, 2018 Category: Cancer & Oncology Authors: Remco J. Molenaar Jaroslaw P. Maciejewski Johanna W. Wilmink Cornelis J. F. van Noorden Source Type: research

The miR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase
The miR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase, Published online: 25 January 2018; doi:10.1038/s41388-017-0091-1The miR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase (Source: Oncogene)
Source: Oncogene - January 25, 2018 Category: Cancer & Oncology Authors: Tianxiang Hu Yating Chong Haiyan Qin Eiko Kitamura Chang-Sheng Chang Jeane Silva Mingqiang Ren John K Cowell Source Type: research

Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production
Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production, Published online: 25 January 2018; doi:10.1038/s41388-017-0120-0Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production (Source: Oncogene)
Source: Oncogene - January 25, 2018 Category: Cancer & Oncology Authors: Hiroyasu Konno Shota Yamauchi Anders Berglund Ryan M. Putney James J. Mul é Glen N. Barber Source Type: research

PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma
PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma, Published online: 25 January 2018; doi:10.1038/s41388-017-0081-3PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma (Source: Oncogene)
Source: Oncogene - January 25, 2018 Category: Cancer & Oncology Authors: Jason A. Hanna Matthew R. Garcia Alicia Lardennois Patrick J. Leavey Dino Maglic Alexandre Fagnan Jonathan C. Go Jordan Roach Yong-Dong Wang David Finkelstein Mark E. Hatley Source Type: research

A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer
A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer, Published online: 25 January 2018; doi:10.1038/s41388-017-0099-6A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer (Source: Oncogene)
Source: Oncogene - January 25, 2018 Category: Cancer & Oncology Authors: Damiano Fantini Alexander P. Glaser Kalen J. Rimar Yiduo Wang Matthew Schipma Nobish Varghese Alfred Rademaker Amir Behdad Aparna Yellapa Yanni Yu Christie Ching-Lin Sze Lu Wang Zibo Zhao Susan E. Crawford Deqing Hu Jonathan D. Licht Clayton K. Collings E Source Type: research

Network analysis of SRC-1 reveals a novel transcription factor hub which regulates endocrine resistant breast cancer
Network analysis of SRC-1 reveals a novel transcription factor hub which regulates endocrine resistant breast cancer, Published online: 25 January 2018; doi:10.1038/s41388-017-0042-xNetwork analysis of SRC-1 reveals a novel transcription factor hub which regulates endocrine resistant breast cancer (Source: Oncogene)
Source: Oncogene - January 25, 2018 Category: Cancer & Oncology Authors: Alacoque L. Browne Sara Charmsaz Damir Vare šlija Ailis Fagan Nicola Cosgrove Sin éad Cocchiglia Siobhan Purcell Elspeth Ward Fiona Bane Lance Hudson Arnold D. Hill Jason S. Carroll Aisling M. Redmond Leonie S. Young Source Type: research

Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination
Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination, Published online: 22 January 2018; doi:10.1038/s41388-017-0069-zGrowth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination (Source: Oncogene)
Source: Oncogene - January 22, 2018 Category: Cancer & Oncology Authors: Yuning Liao Xiaohong Xia Ningning Liu Jianyu Cai Zhiqiang Guo Yanling Li Lili Jiang Q. Ping Dou Daolin Tang Hongbiao Huang Jinbao Liu Source Type: research

MicroRNA-146b promotes PI3K/AKT pathway hyperactivation and thyroid cancer progression by targeting PTEN
MicroRNA-146b promotes PI3K/AKT pathway hyperactivation and thyroid cancer progression by targeting PTEN, Published online: 22 January 2018; doi:10.1038/s41388-017-0088-9MicroRNA-146b promotes PI3K/AKT pathway hyperactivation and thyroid cancer progression by targeting PTEN (Source: Oncogene)
Source: Oncogene - January 22, 2018 Category: Cancer & Oncology Authors: Julia Ram írez-Moya Le ón Wert-Lamas Pilar Santisteban Source Type: research

The BET bromodomain inhibitor CPI203 overcomes resistance to ABT-199 (venetoclax) by downregulation of BFL-1/A1 in in vitro and in vivo models of MYC+/BCL2+ double hit lymphoma
The BET bromodomain inhibitor CPI203 overcomes resistance to ABT-199 (venetoclax) by downregulation of BFL-1/A1 in in vitro and in vivo models of MYC+/BCL2+ double hit lymphoma, Published online: 22 January 2018; doi:10.1038/s41388-017-0111-1The BET bromodomain inhibitor CPI203 overcomes resistance to ABT-199 (venetoclax) by downregulation of BFL-1/A1 in in vitro and in vivo models of MYC+/BCL2+ double hit lymphoma (Source: Oncogene)
Source: Oncogene - January 22, 2018 Category: Cancer & Oncology Authors: A. Esteve-Arenys J. G. Valero A. Chamorro-Jorganes D. Gonzalez V. Rodriguez I. Dlouhy I. Salaverria E. Campo D. Colomer A. Martinez G. Rymkiewicz P. P érez-Galán A. Lopez-Guillermo G. Rou é Source Type: research

CRTC1-MAML2 fusion-induced lncRNA LINC00473 expression maintains the growth and survival of human mucoepidermoid carcinoma cells
CRTC1-MAML2 fusion-induced lncRNA LINC00473 expression maintains the growth and survival of human mucoepidermoid carcinoma cells, Published online: 22 January 2018; doi:10.1038/s41388-017-0104-0CRTC1-MAML2 fusion-induced lncRNA LINC00473 expression maintains the growth and survival of human mucoepidermoid carcinoma cells (Source: Oncogene)
Source: Oncogene - January 22, 2018 Category: Cancer & Oncology Authors: Zirong Chen Shuibin Lin Jian-Liang Li Wei Ni Ruifeng Guo Jianrong Lu Frederic J. Kaye Lizi Wu Source Type: research

IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer
IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer, Published online: 22 January 2018; doi:10.1038/s41388-017-0027-9IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer (Source: Oncogene)
Source: Oncogene - January 22, 2018 Category: Cancer & Oncology Authors: Yinghui Zhang Lynn Wester Jichao He Tamar Geiger Marja Moerkens Ram Siddappa Jean A. Helmijr Mieke M. Timmermans Maxime P. Look Caroline H. M. van Deurzen John W. M. Martens Chantal Pont Marjo de Graauw Erik H. J. Danen Els M. J. J. Berns John H. N. Meerm Source Type: research

Loss of Cdk5 in breast cancer cells promotes ROS-mediated cell death through dysregulation of the mitochondrial permeability transition pore
Loss of Cdk5 in breast cancer cells promotes ROS-mediated cell death through dysregulation of the mitochondrial permeability transition pore, Published online: 19 January 2018; doi:10.1038/s41388-017-0103-1Loss of Cdk5 in breast cancer cells promotes ROS-mediated cell death through dysregulation of the mitochondrial permeability transition pore (Source: Oncogene)
Source: Oncogene - January 19, 2018 Category: Cancer & Oncology Authors: Saranya NavaneethaKrishnan Jesusa L. Rosales Ki-Young Lee Source Type: research

Distinct dependencies on receptor tyrosine kinases in the regulation of MAPK signaling between BRAF V600E and non-V600E mutant lung cancers
Distinct dependencies on receptor tyrosine kinases in the regulation of MAPK signaling between BRAF V600E and non-V600E mutant lung cancers, Published online: 19 January 2018; doi:10.1038/s41388-017-0035-9Distinct dependencies on receptor tyrosine kinases in the regulation of MAPK signaling between BRAF V600E and non-V600E mutant lung cancers (Source: Oncogene)
Source: Oncogene - January 19, 2018 Category: Cancer & Oncology Authors: Hiroshi Kotani Yuta Adachi Hidenori Kitai Shuta Tomida Hideaki Bando Anthony C. Faber Takayuki Yoshino Dominic C. Voon Seiji Yano Hiromichi Ebi Source Type: research