The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutants
The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutants, Published online: 21 June 2018; doi:10.1038/s41388-018-0365-2The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutants (Source: Oncogene)
Source: Oncogene - June 21, 2018 Category: Cancer & Oncology Authors: Jimin Yuan Wan Hwa Ng Paula Y. P. Lam Yu Wang Hongping Xia Jiajun Yap Shou Ping Guan Ann S. G. Lee Mei Wang Manuela Baccarini Jiancheng Hu Source Type: research

PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein
PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein, Published online: 21 June 2018; doi:10.1038/s41388-018-0374-1PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein (Source: Oncogene)
Source: Oncogene - June 21, 2018 Category: Cancer & Oncology Authors: Minggang Peng Jingjing Wang Dongyun Zhang Honglei Jin Jingxia Li Xue-Ru Wu Chuanshu Huang Source Type: research

C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer
C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer, Published online: 21 June 2018; doi:10.1038/s41388-018-0375-0C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer (Source: Oncogene)
Source: Oncogene - June 21, 2018 Category: Cancer & Oncology Authors: Mei-Chun Lin Pin-Hui Chien Hsin-Yi Wu Syue-Ting Chen Hsueh-Fen Juan Pei-Jen Lou Min-Chuan Huang Source Type: research

MacroH2A1.2 inhibits prostate cancer-induced osteoclastogenesis through cooperation with HP1α and H1.2
MacroH2A1.2 inhibits prostate cancer-induced osteoclastogenesis through cooperation with HP1α and H1.2MacroH2A1.2 inhibits prostate cancer-induced osteoclastogenesis through cooperation with HP1α and H1.2, Published online: 20 June 2018; doi:10.1038/s41388-018-0356-3MacroH2A1.2 inhibits prostate cancer-induced osteoclastogenesis through cooperation with HP1α and H1.2 (Source: Oncogene)
Source: Oncogene - June 20, 2018 Category: Cancer & Oncology Authors: Jin-Man Kim Yonghwan Shin Sunyoung Lee Mi Yeong Kim Vasu Punj Hong-In Shin Kyunghwan Kim Jung-Min Koh Daewon Jeong Woojin An Source Type: research

The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis
The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis, Published online: 20 June 2018; doi:10.1038/s41388-018-0376-zThe homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis (Source: Oncogene)
Source: Oncogene - June 20, 2018 Category: Cancer & Oncology Authors: Tianliang He Min Jin Chenxi Xu Zhongjun Ma Fufang Wu Xiaobo Zhang Source Type: research

Metformin sensitizes endometrial cancer cells to chemotherapy through IDH1-induced Nrf2 expression via an epigenetic mechanism
Metformin sensitizes endometrial cancer cells to chemotherapy through IDH1-induced Nrf2 expression via an epigenetic mechanism, Published online: 19 June 2018; doi:10.1038/s41388-018-0360-7Metformin sensitizes endometrial cancer cells to chemotherapy through IDH1-induced Nrf2 expression via an epigenetic mechanism (Source: Oncogene)
Source: Oncogene - June 19, 2018 Category: Cancer & Oncology Authors: Mingzhu Bai Linlin Yang Hong Liao Xiaoyan Liang Bingying Xie Ji Xiong Xiang Tao Xiong Chen Yali Cheng Xiaojun Chen Youji Feng Zhenbo Zhang Wenxin Zheng Source Type: research

The dynamic and stress-adaptive signaling hub of 14-3-3: emerging mechanisms of regulation and context-dependent protein–protein interactions
The dynamic and stress-adaptive signaling hub of 14-3-3: emerging mechanisms of regulation and context-dependent protein–protein interactionsThe dynamic and stress-adaptive signaling hub of 14-3-3: emerging mechanisms of regulation and context-dependent protein–protein interactions, Published online: 18 June 2018; doi:10.1038/s41388-018-0348-3The dynamic and stress-adaptive signaling hub of 14-3-3: emerging mechanisms of regulation and context-dependent protein–protein interactions (Source: Oncogene)
Source: Oncogene - June 18, 2018 Category: Cancer & Oncology Authors: KL Pennington TY Chan MP Torres JL Andersen Source Type: research

O-GlcNAcylation mediates metastasis of cholangiocarcinoma through FOXO3 and MAN1A1
O-GlcNAcylation mediates metastasis of cholangiocarcinoma through FOXO3 and MAN1A1, Published online: 18 June 2018; doi:10.1038/s41388-018-0366-1O-GlcNAcylation mediates metastasis of cholangiocarcinoma through FOXO3 and MAN1A1 (Source: Oncogene)
Source: Oncogene - June 18, 2018 Category: Cancer & Oncology Authors: Chatchai Phoomak Atit Silsirivanit Dayoung Park Kanlayanee Sawanyawisuth Kulthida Vaeteewoottacharn Chaisiri Wongkham Eric W.-F. Lam Chawalit Pairojkul Carlito B. Lebrilla Sopit Wongkham Source Type: research

Identification of highly penetrant Rb-related synthetic lethal interactions in triple negative breast cancer
Identification of highly penetrant Rb-related synthetic lethal interactions in triple negative breast cancer, Published online: 18 June 2018; doi:10.1038/s41388-018-0368-zIdentification of highly penetrant Rb-related synthetic lethal interactions in triple negative breast cancer (Source: Oncogene)
Source: Oncogene - June 18, 2018 Category: Cancer & Oncology Authors: Rachel Brough Aditi Gulati Syed Haider Rahul Kumar James Campbell Erik Knudsen Stephen J. Pettitt Colm J. Ryan Christopher J. Lord Source Type: research

Na+,HCO3–-cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice
Na+,HCO3–-cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in miceNa+,HCO3–-cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice, Published online: 15 June 2018; doi:10.1038/s41388-018-0353-6Na+,HCO3–-cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice (Source: Oncogene)
Source: Oncogene - June 15, 2018 Category: Cancer & Oncology Authors: Soojung Lee Trine V. Axelsen Nicolai Jessen Stine F. Pedersen Pernille Vahl Ebbe Boedtkjer Source Type: research

miR-30 disrupts senescence and promotes cancer by targeting both p16INK4A and DNA damage pathways
miR-30 disrupts senescence and promotes cancer by targeting both p16INK4A and DNA damage pathways, Published online: 15 June 2018; doi:10.1038/s41388-018-0358-1miR-30 disrupts senescence and promotes cancer by targeting both p16INK4A and DNA damage pathways (Source: Oncogene)
Source: Oncogene - June 15, 2018 Category: Cancer & Oncology Authors: Weijun Su Lixin Hong Xin Xu Shan Huang Denise Herpai Lisheng Li Yingxi Xu Lan Truong Wen-Yuan Hu Xiaohua Wu Changchun Xiao Wei Zhang Jiahuai Han Waldemar Debinski Rong Xiang Peiqing Sun Source Type: research

Massive expression of germ cell-specific genes is a hallmark of cancer and a potential target for novel treatment development
Massive expression of germ cell-specific genes is a hallmark of cancer and a potential target for novel treatment development, Published online: 15 June 2018; doi:10.1038/s41388-018-0357-2Massive expression of germ cell-specific genes is a hallmark of cancer and a potential target for novel treatment development (Source: Oncogene)
Source: Oncogene - June 15, 2018 Category: Cancer & Oncology Authors: Jan Willem Bruggeman Jan Koster Paul Lodder Sjoerd Repping Geert Hamer Source Type: research

hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis
hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axishMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis, Published online: 15 June 2018; doi:10.1038/s41388-018-0364-3hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis (Source: Oncogene)
Source: Oncogene - June 15, 2018 Category: Cancer & Oncology Authors: Francesca Di Modugno Sheila Spada Belinda Palermo Paolo Visca Pierluigi Iapicca Anna Di Carlo Barbara Antoniani Isabella Sperduti Anna Di Benedetto Irene Terrenato Marcella Mottolese Francesco Gandolfi Francesco Facciolo Emily I. Chen Martin A. Schwartz A Source Type: research

Targeting PRPK and TOPK for skin cancer prevention and therapy
Targeting PRPK and TOPK for skin cancer prevention and therapy, Published online: 14 June 2018; doi:10.1038/s41388-018-0350-9Targeting PRPK and TOPK for skin cancer prevention and therapy (Source: Oncogene)
Source: Oncogene - June 14, 2018 Category: Cancer & Oncology Authors: Eunmiri Roh Mee-Hyun Lee Tatyana A. Zykova Feng Zhu Janos Nadas Hong-Gyum Kim Ki Beom Bae Yan Li Yong Yeon Cho Clara Curiel-Lewandrowski Janine Einspahr Sally E. Dickinson Ann M. Bode Zigang Dong Source Type: research

The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src
The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src, Published online: 13 June 2018; doi:10.1038/s41388-018-0354-5The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src (Source: Oncogene)
Source: Oncogene - June 13, 2018 Category: Cancer & Oncology Authors: Gun-Woo Lee Jun Bum Park Sung Yeon Park Jieun Seo Seung-Hyun Shin Jong-Wan Park Sang Jung Kim Masatoshi Watanabe Yang-Sook Chun Source Type: research

LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation
LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation, Published online: 13 June 2018; doi:10.1038/s41388-018-0352-7LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation (Source: Oncogene)
Source: Oncogene - June 13, 2018 Category: Cancer & Oncology Authors: Kaixuan Zeng Xiaoxiang Chen Xiuxiu Hu Xiangxiang Liu Tao Xu Huiling Sun Yuqin Pan Bangshun He Shukui Wang Source Type: research

TRPS1 regulates oestrogen receptor binding and histone acetylation at enhancers
TRPS1 regulates oestrogen receptor binding and histone acetylation at enhancers, Published online: 12 June 2018; doi:10.1038/s41388-018-0312-2TRPS1 regulates oestrogen receptor binding and histone acetylation at enhancers (Source: Oncogene)
Source: Oncogene - June 12, 2018 Category: Cancer & Oncology Authors: A. A. Serandour H. Mohammed A. Miremadi K. W. Mulder J. S. Carroll Source Type: research

Inhibition of maternal embryonic leucine zipper kinase with OTSSP167 displays potent anti-leukemic effects in chronic lymphocytic leukemia
Inhibition of maternal embryonic leucine zipper kinase with OTSSP167 displays potent anti-leukemic effects in chronic lymphocytic leukemia, Published online: 12 June 2018; doi:10.1038/s41388-018-0333-xInhibition of maternal embryonic leucine zipper kinase with OTSSP167 displays potent anti-leukemic effects in chronic lymphocytic leukemia (Source: Oncogene)
Source: Oncogene - June 12, 2018 Category: Cancer & Oncology Authors: Ya Zhang Xiangxiang Zhou Ying Li Yangyang Xu Kang Lu Peipei Li Xin Wang Source Type: research

β-catenin/TCF activity regulates IGF-1R tyrosine kinase inhibitor sensitivity in colon cancer
β-catenin/TCF activity regulates IGF-1R tyrosine kinase inhibitor sensitivity in colon cancerβ-catenin/TCF activity regulates IGF-1R tyrosine kinase inhibitor sensitivity in colon cancer, Published online: 12 June 2018; doi:10.1038/s41388-018-0362-5β-catenin/TCF activity regulates IGF-1R tyrosine kinase inhibitor sensitivity in colon cancer (Source: Oncogene)
Source: Oncogene - June 12, 2018 Category: Cancer & Oncology Authors: Hani Lee Nayoung Kim Young Ji Yoo Hyejin Kim Euna Jeong SeokGyeong Choi Sung Un Moon Seung Hyun Oh Gordon B. Mills Sukjoon Yoon Woo-Young Kim Source Type: research

Exosome-mediated transfer of lncRUNX2-AS1 from multiple myeloma cells to MSCs contributes to osteogenesis
Exosome-mediated transfer of lncRUNX2-AS1 from multiple myeloma cells to MSCs contributes to osteogenesis, Published online: 12 June 2018; doi:10.1038/s41388-018-0359-0Exosome-mediated transfer of lncRUNX2-AS1 from multiple myeloma cells to MSCs contributes to osteogenesis (Source: Oncogene)
Source: Oncogene - June 12, 2018 Category: Cancer & Oncology Authors: Bingzong Li Hongxia Xu Huiying Han Sha Song Xiaojuan Zhang Lu Ouyang Chen ’ao Qian Yating Hong Yingchun Qiu Wenqi Zhou Moli Huang Wenzhuo Zhuang Source Type: research

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity
YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity, Published online: 11 June 2018; doi:10.1038/s41388-018-0301-5YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity (Source: Oncogene)
Source: Oncogene - June 11, 2018 Category: Cancer & Oncology Authors: Olivia M. Yu Jorge A. Benitez Steven W. Plouffe Daniel Ryback Andrea Klein Jeff Smith Jason Greenbaum Benjamin Delatte Anjana Rao Kun-Liang Guan Frank B. Furnari Olga Meiri Chaim Shigeki Miyamoto Joan Heller Brown Source Type: research

Forkhead box C1 promotes colorectal cancer metastasis through transactivating ITGA7 and FGFR4 expression
Forkhead box C1 promotes colorectal cancer metastasis through transactivating ITGA7 and FGFR4 expression, Published online: 08 June 2018; doi:10.1038/s41388-018-0355-4Forkhead box C1 promotes colorectal cancer metastasis through transactivating ITGA7 and FGFR4 expression (Source: Oncogene)
Source: Oncogene - June 8, 2018 Category: Cancer & Oncology Authors: Jian Liu Zhe Zhang Xiaowei Li Jie Chen Guodong Wang Zuhong Tian Meirui Qian Zhangqian Chen Hao Guo Guangbo Tang Wenjie Huang Dean Tian Daowen Wang Yongzhan Nie Daiming Fan Kaichun Wu Limin Xia Source Type: research

Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma
Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma, Published online: 07 June 2018; doi:10.1038/s41388-018-0326-9Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma (Source: Oncogene)
Source: Oncogene - June 7, 2018 Category: Cancer & Oncology Authors: Shuobo Boboila Gonzalo Lopez Jiyang Yu Debarshi Banerjee Angela Kadenhe-Chiweshe Eileen P. Connolly Jessica J. Kandel Presha Rajbhandari Jose M. Silva Andrea Califano Darrell J. Yamashiro Source Type: research

Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma
Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma, Published online: 07 June 2018; doi:10.1038/s41388-018-0342-9Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma (Source: Oncogene)
Source: Oncogene - June 7, 2018 Category: Cancer & Oncology Authors: Yunjung Kim Aya Shiba-Ishii Tomoki Nakagawa Shun-ichiro Iemura Tohru Natsume Noriyuki Nakano Ryota Matsuoka Shingo Sakashita SangJoon Lee Atsushi Kawaguchi Yukio Sato Masayuki Noguchi Source Type: research

Functional characterization of lysosomal interaction of Akt with VRK2
Functional characterization of lysosomal interaction of Akt with VRK2, Published online: 05 June 2018; doi:10.1038/s41388-018-0330-0Functional characterization of lysosomal interaction of Akt with VRK2 (Source: Oncogene)
Source: Oncogene - June 5, 2018 Category: Cancer & Oncology Authors: Noriyuki Hirata Futoshi Suizu Mami Matsuda-Lennikov Tsutomu Tanaka Tatsuma Edamura Satoko Ishigaki Thoria Donia Pathrapol Lithanatudom Chikashi Obuse Toshihiko Iwanaga Masayuki Noguchi Source Type: research

The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma
The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma, Published online: 05 June 2018; doi:10.1038/s41388-018-0315-zThe glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma (Source: Oncogene)
Source: Oncogene - June 5, 2018 Category: Cancer & Oncology Authors: Heike Miess Beatrice Dankworth Arvin M. Gouw Mathias Rosenfeldt Werner Schmitz Ming Jiang Becky Saunders Michael Howell Julian Downward Dean W. Felsher Barrie Peck Almut Schulze Source Type: research

Epithelial membrane protein 1 promotes tumor metastasis by enhancing cell migration via copine-III and Rac1
Epithelial membrane protein 1 promotes tumor metastasis by enhancing cell migration via copine-III and Rac1, Published online: 04 June 2018; doi:10.1038/s41388-018-0286-0Epithelial membrane protein 1 promotes tumor metastasis by enhancing cell migration via copine-III and Rac1 (Source: Oncogene)
Source: Oncogene - June 4, 2018 Category: Cancer & Oncology Authors: Mohammad Khusni B. Ahmat Amin Akio Shimizu Dimitar P. Zankov Akira Sato Souichi Kurita Masami Ito Toshinaga Maeda Tetsuya Yoshida Tomohisa Sakaue Shigeki Higashiyama Akihiro Kawauchi Hisakazu Ogita Source Type: research

TRIM14 promotes chemoresistance in gliomas by activating Wnt/β-catenin signaling via stabilizing Dvl2
TRIM14 promotes chemoresistance in gliomas by activating Wnt/β-catenin signaling via stabilizing Dvl2TRIM14 promotes chemoresistance in gliomas by activating Wnt/β-catenin signaling via stabilizing Dvl2, Published online: 04 June 2018; doi:10.1038/s41388-018-0344-7TRIM14 promotes chemoresistance in gliomas by activating Wnt/β-catenin signaling via stabilizing Dvl2 (Source: Oncogene)
Source: Oncogene - June 4, 2018 Category: Cancer & Oncology Authors: Zhanyao Tan Libing Song Wenjiao Wu Yanqing Zhou Jinrong Zhu Geyan Wu Lixue Cao Junwei Song Jun Li Wei Zhang Source Type: research

FGFR1-ERK1/2-SOX2 axis promotes cell proliferation, epithelial–mesenchymal transition, and metastasis in FGFR1-amplified lung cancer
FGFR1-ERK1/2-SOX2 axis promotes cell proliferation, epithelial–mesenchymal transition, and metastasis in FGFR1-amplified lung cancerFGFR1-ERK1/2-SOX2 axis promotes cell proliferation, epithelial–mesenchymal transition, and metastasis in FGFR1-amplified lung cancer, Published online: 01 June 2018; doi:10.1038/s41388-018-0311-3FGFR1-ERK1/2-SOX2 axis promotes cell proliferation, epithelial–mesenchymal transition, and metastasis in FGFR1-amplified lung cancer (Source: Oncogene)
Source: Oncogene - June 1, 2018 Category: Cancer & Oncology Authors: Kaixuan Wang Wenxiang Ji Yongfeng Yu Ziming Li Xiaomin Niu Weiliang Xia Shun Lu Source Type: research

SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells
SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells, Published online: 01 June 2018; doi:10.1038/s41388-018-0335-8SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells (Source: Oncogene)
Source: Oncogene - June 1, 2018 Category: Cancer & Oncology Authors: Mitsuro Kanda Haruyoshi Tanaka Dai Shimizu Takashi Miwa Shinichi Umeda Chie Tanaka Daisuke Kobayashi Norifumi Hattori Masaya Suenaga Masamichi Hayashi Naoki Iwata Suguru Yamada Michitaka Fujiwara Yasuhiro Kodera Source Type: research

Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1
Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1, Published online: 01 June 2018; doi:10.1038/s41388-018-0294-0Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1 (Source: Oncogene)
Source: Oncogene - June 1, 2018 Category: Cancer & Oncology Authors: Zainab Al Shareef Hoda Kardooni Virginia Murillo-Garz ón Giacomo Domenici Emmanouil Stylianakis Jennifer H. Steel Miriam Rabano Irantzu Gorro ño-Etxebarria Ignacio Zabalza Maria dM Vivanco Jonathan Waxman Robert M. Kypta Source Type: research

BCL-2 selective inhibitor ABT-199 primes rhabdomyosarcoma cells to histone deacetylase inhibitor-induced apoptosis
BCL-2 selective inhibitor ABT-199 primes rhabdomyosarcoma cells to histone deacetylase inhibitor-induced apoptosis, Published online: 01 June 2018; doi:10.1038/s41388-018-0212-5BCL-2 selective inhibitor ABT-199 primes rhabdomyosarcoma cells to histone deacetylase inhibitor-induced apoptosis (Source: Oncogene)
Source: Oncogene - June 1, 2018 Category: Cancer & Oncology Authors: Ulrike Heinicke Tinka Haydn Sarah Kehr Meike Vogler Simone Fulda Source Type: research

Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide
Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide, Published online: 31 May 2018; doi:10.1038/s41388-018-0340-yActivation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with niclosamide (Source: Oncogene)
Source: Oncogene - May 31, 2018 Category: Cancer & Oncology Authors: Lu Lu Jiali Dong Lili Wang Qing Xia Dan Zhang Hyejin Kim Tao Yin Saijun Fan Qiang Shen Source Type: research

Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4–miR-18a pathway in cervical cancer
Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4–miR-18a pathway in cervical cancerControl of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4–miR-18a pathway in cervical cancer, Published online: 31 May 2018; doi:10.1038/s41388-018-0347-4Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4–miR-18a pathway in cervical cancer (Source: Oncogene)
Source: Oncogene - May 31, 2018 Category: Cancer & Oncology Authors: Peixin Dong Ying Xiong Jiehai Yu Lin Chen Tang Tao Song Yi Sharon J.B. Hanley Junming Yue Hidemichi Watari Noriaki Sakuragi Source Type: research

Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option
Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option, Published online: 31 May 2018; doi:10.1038/s41388-018-0288-yImmune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option (Source: Oncogene)
Source: Oncogene - May 31, 2018 Category: Cancer & Oncology Authors: Hauke Stamm Felix Klingler Eva-Maria Grossjohann Jana Muschhammer Eik Vettorazzi Michael Heuser Ulrike Mock Felicitas Thol Gabi Vohwinkel Emily Latuske Carsten Bokemeyer Roman Kischel Cedric Dos Santos Sabine Stienen Matthias Friedrich Michael Lutteropp D Source Type: research

Heterozygous IDH1 R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAP
Heterozygous IDH1 R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAPHeterozygous IDH1 R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAP, Published online: 30 May 2018; doi:10.1038/s41388-018-0334-9Heterozygous IDH1 R132H/WT created by “single base editing” inhibits human astroglial cell growth by downregulating YAP (Source: Oncogene)
Source: Oncogene - May 30, 2018 Category: Cancer & Oncology Authors: Shuang Wei Jie Wang Olutobi Oyinlade Ding Ma Shuyan Wang Lisa Kratz Bachchu Lal Qingfu Xu Senquan Liu Sagar R. Shah Hao Zhang Yunqing Li Alfredo Qui ñones-Hinojosa Heng Zhu Zhi-yong Huang Linzhao Cheng Jiang Qian Shuli Xia Source Type: research

Pentose conversions support the tumorigenesis of pancreatic cancer distant metastases
Pentose conversions support the tumorigenesis of pancreatic cancer distant metastases, Published online: 30 May 2018; doi:10.1038/s41388-018-0346-5Pentose conversions support the tumorigenesis of pancreatic cancer distant metastases (Source: Oncogene)
Source: Oncogene - May 30, 2018 Category: Cancer & Oncology Authors: Matthew E. Bechard Anna E. Word Amanda V. Tran Xiaojing Liu Jason W. Locasale Oliver G. McDonald Source Type: research

The p21-activated kinase 4-Slug transcription factor axis promotes epithelial−mesenchymal transition and worsens prognosis in prostate cancer
The p21-activated kinase 4-Slug transcription factor axis promotes epithelial−mesenchymal transition and worsens prognosis in prostate cancerThe p21-activated kinase 4-Slug transcription factor axis promotes epithelial−mesenchymal transition and worsens prognosis in prostate cancer, Published online: 30 May 2018; doi:10.1038/s41388-018-0327-8The p21-activated kinase 4-Slug transcription factor axis promotes epithelial−mesenchymal transition and worsens prognosis in prostate cancer (Source: Oncogene)
Source: Oncogene - May 30, 2018 Category: Cancer & Oncology Authors: Jung-Jin Park Mee-Hee Park Eun Hye Oh Nak-Kyun Soung Soo Jae Lee Jae-Kyung Jung Ok-Jun Lee Seok Joong Yun Wun-Jae Kim Eun-Young Shin Eung-Gook Kim Source Type: research

Helicobacter pylori pathogen regulates p14ARF tumor suppressor and autophagy in gastric epithelial cells
Helicobacter pylori pathogen regulates p14ARF tumor suppressor and autophagy in gastric epithelial cells, Published online: 30 May 2018; doi:10.1038/s41388-018-0343-8Helicobacter pylori pathogen regulates p14ARF tumor suppressor and autophagy in gastric epithelial cells (Source: Oncogene)
Source: Oncogene - May 30, 2018 Category: Cancer & Oncology Authors: Andela Horvat Jennifer M. Noto Balamurugan Ramatchandirin Elena Zaika Manikandan Palrasu Jinxiong Wei Barbara G. Schneider Wael El-Rifai Richard M. Peek Jr Alexander I. Zaika Source Type: research

Mex-3B induces apoptosis by inhibiting miR-92a access to the Bim-3′UTR
Mex-3B induces apoptosis by inhibiting miR-92a access to the Bim-3′UTRMex-3B induces apoptosis by inhibiting miR-92a access to the Bim-3′UTR, Published online: 30 May 2018; doi:10.1038/s41388-018-0336-7Mex-3B induces apoptosis by inhibiting miR-92a access to the Bim-3′UTR (Source: Oncogene)
Source: Oncogene - May 30, 2018 Category: Cancer & Oncology Authors: Takeaki Oda Yusuke Yamazumi Takatoshi Hiroko Atsushi Kamiya Saori Kiriya Saki Suyama Yumi Shiozaki-Sato Tetsu Akiyama Source Type: research

mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy
mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy, Published online: 30 May 2018; doi:10.1038/s41388-018-0345-6mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy (Source: Oncogene)
Source: Oncogene - May 30, 2018 Category: Cancer & Oncology Authors: Seung Un Seo Seon Min Woo Hyun-Shik Lee Sang Hyun Kim Kyoung-jin Min Taeg Kyu Kwon Source Type: research

Maintenance and pharmacologic targeting of ROR1 protein levels via UHRF1 in t(1;19) pre-B-ALL
Maintenance and pharmacologic targeting of ROR1 protein levels via UHRF1 in t(1;19) pre-B-ALL, Published online: 30 May 2018; doi:10.1038/s41388-018-0299-8Maintenance and pharmacologic targeting of ROR1 protein levels via UHRF1 in t(1;19) pre-B-ALL (Source: Oncogene)
Source: Oncogene - May 30, 2018 Category: Cancer & Oncology Authors: Marilynn Chow Lina Gao Jason D. MacManiman Vincent T. Bicocca Bill H. Chang Joshi J. Alumkal Jeffrey W. Tyner Source Type: research

Cervical cancer is addicted to SIRT1 disarming the AIM2 antiviral defense
Cervical cancer is addicted to SIRT1 disarming the AIM2 antiviral defense, Published online: 29 May 2018; doi:10.1038/s41388-018-0339-4Cervical cancer is addicted to SIRT1 disarming the AIM2 antiviral defense (Source: Oncogene)
Source: Oncogene - May 29, 2018 Category: Cancer & Oncology Authors: Daeho So Hyun-Woo Shin Jiyoung Kim Mingyu Lee Jongyun Myeong Yang-Sook Chun Jong-Wan Park Source Type: research

Loss of MAOA in epithelia inhibits adenocarcinoma development, cell proliferation and cancer stem cells in prostate
Loss of MAOA in epithelia inhibits adenocarcinoma development, cell proliferation and cancer stem cells in prostate, Published online: 29 May 2018; doi:10.1038/s41388-018-0325-xLoss of MAOA in epithelia inhibits adenocarcinoma development, cell proliferation and cancer stem cells in prostate (Source: Oncogene)
Source: Oncogene - May 29, 2018 Category: Cancer & Oncology Authors: Chun-Peng Liao Tzu-Ping Lin Pei-Chuan Li Lauren A. Geary Kevin Chen Vijaya Pooja Vaikari Jason Boyang Wu Chi-Hung Lin Mitchell E. Gross Jean C. Shih Source Type: research

Melanoma protective antitumor immunity activated by catalytic DNA
Melanoma protective antitumor immunity activated by catalytic DNA, Published online: 29 May 2018; doi:10.1038/s41388-018-0306-0Melanoma protective antitumor immunity activated by catalytic DNA (Source: Oncogene)
Source: Oncogene - May 29, 2018 Category: Cancer & Oncology Authors: Hong Cai Eun-Ae Cho Yue Li Jim Sockler Christopher R. Parish Beng H. Chong Jarem Edwards Tristan J. Dodds Peter M. Ferguson James S. Wilmott Richard A. Scolyer Gary M. Halliday Levon M. Khachigian Source Type: research

RANK-c attenuates aggressive properties of ER-negative breast cancer by inhibiting NF-κB activation and EGFR signaling
RANK-c attenuates aggressive properties of ER-negative breast cancer by inhibiting NF-κB activation and EGFR signalingRANK-c attenuates aggressive properties of ER-negative breast cancer by inhibiting NF-κB activation and EGFR signaling, Published online: 29 May 2018; doi:10.1038/s41388-018-0324-yRANK-c attenuates aggressive properties of ER-negative breast cancer by inhibiting NF-κB activation and EGFR signaling (Source: Oncogene)
Source: Oncogene - May 29, 2018 Category: Cancer & Oncology Authors: Chaido Sirinian Anastasios D. Papanastasiou Michail Schizas Magda Spella Georgios T. Stathopoulos Maria Repanti Ioannis K. Zarkadis Tari A. King Haralabos P. Kalofonos Source Type: research

Myeloid-restricted ablation of Shp2 restrains melanoma growth by amplifying the reciprocal promotion of CXCL9 and IFN-γ production in tumor microenvironment
Myeloid-restricted ablation of Shp2 restrains melanoma growth by amplifying the reciprocal promotion of CXCL9 and IFN-γ production in tumor microenvironmentMyeloid-restricted ablation of Shp2 restrains melanoma growth by amplifying the reciprocal promotion of CXCL9 and IFN-γ production in tumor microenvironment, Published online: 24 May 2018; doi:10.1038/s41388-018-0337-6Myeloid-restricted ablation of Shp2 restrains melanoma growth by amplifying the reciprocal promotion of CXCL9 and IFN-γ production in tumor microenvironment (Source: Oncogene)
Source: Oncogene - May 24, 2018 Category: Cancer & Oncology Authors: P. Xiao Y. Guo H. Zhang X. Zhang H. Cheng Q. Cao Y. Ke Source Type: research

Artemisitene suppresses tumorigenesis by inducing DNA damage through deregulating c-Myc-topoisomerase pathway
Artemisitene suppresses tumorigenesis by inducing DNA damage through deregulating c-Myc-topoisomerase pathway, Published online: 24 May 2018; doi:10.1038/s41388-018-0331-zArtemisitene suppresses tumorigenesis by inducing DNA damage through deregulating c-Myc-topoisomerase pathway (Source: Oncogene)
Source: Oncogene - May 24, 2018 Category: Cancer & Oncology Authors: Jian Chen Wenjuan Li Ke Cui Kaiyuan Ji Shuxiang Xu Yang Xu Source Type: research

K6 linked polyubiquitylation of FADD by CHIP prevents death inducing signaling complex formation suppressing cell death
K6 linked polyubiquitylation of FADD by CHIP prevents death inducing signaling complex formation suppressing cell death, Published online: 23 May 2018; doi:10.1038/s41388-018-0323-zK6 linked polyubiquitylation of FADD by CHIP prevents death inducing signaling complex formation suppressing cell death (Source: Oncogene)
Source: Oncogene - May 23, 2018 Category: Cancer & Oncology Authors: Jinho Seo Eun-Woo Lee Jihye Shin Daehyeon Seong Young Woo Nam Manhyung Jeong Seon-Hyeong Lee Cheolju Lee Jaewhan Song Source Type: research

Integration of Ca2+ signaling regulates the breast tumor cell response to simvastatin and doxorubicin
Integration of Ca2+ signaling regulates the breast tumor cell response to simvastatin and doxorubicin, Published online: 23 May 2018; doi:10.1038/s41388-018-0329-6Integration of Ca2+ signaling regulates the breast tumor cell response to simvastatin and doxorubicin (Source: Oncogene)
Source: Oncogene - May 23, 2018 Category: Cancer & Oncology Authors: Souleymane Abdoul-Azize Catherine Buquet Hong Li Jean-Michel Picquenot Jean-Pierre Vannier Source Type: research