An in vitro comparison of intra-operative isohemagglutinin and human leukocyte antigen removal techniques in pediatric heart transplantation
CONCLUSIONS: In this in vitro plasmapheresis model of IT and anti-HLA antibody reduction, both MP and CP incorporated into the EC circuit can be used quickly and effectively to reduce circulating antibodies. While CP may have some greater efficiency, further study is necessary to verify this in vivo.PMID:38099633 | PMC:PMC10723569 | DOI:10.1051/ject/2023034 (Source: Journal of Extra-Corporeal Technology)
Source: Journal of Extra-Corporeal Technology - December 15, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Emily A Hayes Ashley B Walczak Erin Goodhue Meyer Kathleen Nicol Matthew Deitemyer Vicky Duffy Michelle Moore Padilla Robert J Gajarski Deipanjan Nandi Source Type: research

Direct and continuous dosing of propofol can saturate Ex vivo ECMO circuit to improve propofol recovery
CONCLUSION: Our results suggest that if ECMO circuits are dosed directly with propofol, drug adsorption can be eliminated as a cause for altered drug exposure. Field of Research: Artificial Lung/ECMO.PMID:38099634 | PMC:PMC10723571 | DOI:10.1051/ject/2023036 (Source: Journal of Extra-Corporeal Technology)
Source: Journal of Extra-Corporeal Technology - December 15, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Nitish Khurana Till S ünner Oliver Hubbard Carina E Imburgia Venkata Yellepeddi Hamidreza Ghandehari Kevin M Watt Source Type: research

ECPR for prolonged Pediatric Cardiac Arrest, an outcome without major neurological compromise
We report a case of a 4-month-old patient with a history of ventricular and septal defects, with left to right shunt and enlargement of left heart chambers that underwent surgery for the closure of the atrial and septal defects, and experienced complications that led to the use of ECMO in response to a prolonged cardiac arrest.PMID:38099635 | PMC:PMC10723570 | DOI:10.1051/ject/2023019 (Source: Journal of Extra-Corporeal Technology)
Source: Journal of Extra-Corporeal Technology - December 15, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Laura Guti érrez-Soriano Eduardo Becerra Zapata Nicolas Maya Trujillo German Andres Franco Gruntorad Pedro Hurtado Pe ña Source Type: research

Fifth-time redo mitral valve replacement via right thoracotomy under systemic hyperkalemia cardiopulmonary bypass without aortic cross-clamp
We report a case of a 46-year-old female patient who had a history of four cardiac operations. We chose a mitral valve replacement via right thoracotomy to enable optimal exposure of the mitral valve (MV). Because of multi-reoperations, we employed systemic hyperkalemia for cardiac arrest to protect the heart during cardiopulmonary bypass (CPB) without aortic cross-clamping. Here, we present a complex operation that performed management of CPB under hyperkalemia and the patient had a good postoperative recovery.PMID:38099636 | PMC:PMC10723575 | DOI:10.1051/ject/2023040 (Source: Journal of Extra-Corporeal Technology)
Source: Journal of Extra-Corporeal Technology - December 15, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Tomohisa Takeichi Yoshihisa Morimoto Akitoshi Yamada Takanori Tanaka Source Type: research

Central ECMO cannulation for severe dihydropyridine calcium channel blocker overdose
We present a case of a 12-year-old with severe dihydropyridine CCB ingestion, refractory to medical management and successfully treated with central ECMO cannulation. The patient was discharged home with no significant disability. Central ECMO cannulation may be helpful to facilitate adequate flows in vasodilatory shock such as CCB overdose.PMID:38099637 | PMC:PMC10723573 | DOI:10.1051/ject/2023037 (Source: Journal of Extra-Corporeal Technology)
Source: Journal of Extra-Corporeal Technology - December 15, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Jose M Cardenas Santiago Borasino Joseph Timpa Jeremy Hawkins Martha McBride William Rushton Jordan Newman Erika Mendoza Robert Sorabella Jonathan Byrnes Source Type: research