Novel STAT1 Variants in Japanese Patients with Isolated Mendelian Susceptibility to Mycobacterial Diseases
ConclusionFour kindred MSMD subjects with 3 novel variants and 1 known variant inSTAT1 were identified in this study. AD STAT1 deficiency might be prevalent in Japanese patients with BCG-associated MSMD. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - November 7, 2022 Category: Allergy & Immunology Source Type: research
Disseminated Acanthamoeba Infection in a Bone Marrow Transplant Recipient with CTLA-4 Haploinsufficiency
(Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - November 7, 2022 Category: Allergy & Immunology Source Type: research
Combination of WFDC2, CHI3L1, and KRT19 in Plasma Defines a Clinically Useful Molecular Phenotype Associated with Prognosis in Critically Ill COVID-19 Patients
ConclusionThe use of these easily measured key proteins offered new insight into the pathogenesis of COVID-19 and could be useful in a potential clinical application. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - November 4, 2022 Category: Allergy & Immunology Source Type: research
MAGT1 Gene Mutation is Associated with Myositis and CD127 Expression Downregulation
(Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - November 4, 2022 Category: Allergy & Immunology Source Type: research
Lentiviral Gene Transfer Corrects Immune Abnormalities in XIAP Deficiency
ConclusionGene correction of HSCs recovers XIAP-dependent immune defects and could offer a treatment option for patients with XIAP deficiency. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - November 3, 2022 Category: Allergy & Immunology Source Type: research
