Special considerations in the design and implementation of pediatric otoprotection trials
ConclusionsFuture pediatric otoprotection trials should emphasize (1) deep integration of preclinical and early-phase studies; (2) an embedded or free-standing design for systemic agents based on mechanistic considerations; (3) use of suitable audiologic testing batteries for children, SIOP grading criteria, and submission of raw audiologic data for central review; and (4) novel endpoints and innovative study designs that maximize trial efficiency for limited sample sizes. Additional recommendations include routine collection of DNA specimens for assessing modifying effects of genetic susceptibility and meaningful inclusio...
Source: Journal of Cancer Survivorship - January 13, 2023 Category: Cancer & Oncology Source Type: research
The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review
ConclusionsOtotoxicity has a negative long-term impact on multiple areas of life for adults and children LWBC. This can compromise their quality of life.Implications for cancer survivorsIncreased awareness, monitoring and education surrounding these issues may lead to earlier intervention and better management of ototoxicity, enhancing the quality of life of people LWBC. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - January 13, 2023 Category: Cancer & Oncology Source Type: research
Introduction to the special section: treatment-related hearing loss and its impact on cancer survivors
(Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - January 13, 2023 Category: Cancer & Oncology Source Type: research
Mobile health (mHealth) interventions in prostate cancer survivorship: a scoping review
Conclusions and implications for cancer survivorsThe improving survival rates from CaP suggest that men are now living longer with unfavorable treatment side effects such as reduced sexual functioning, pain, and fatigue. Hence, mHealth represents new hope in men ’s illness trajectory. However, current application in patients’ care pathways remains poor, particularly in the active phase of CaP management. Efforts must be accelerated to explore individual and healthcare-level drivers of mHealth use. The feasibility and descriptive nature of current studie s point to a lack of attention to actual implementation and scale-...
Source: Journal of Cancer Survivorship - January 11, 2023 Category: Cancer & Oncology Source Type: research
Evaluation of quality, readability, suitability, and usefulness of online resources available to cancer survivors
ConclusionQuality and suitability were fair, whereas readability exceeded recommended levels. Only one resource had a superior score in both quality and suitability.Implications for Cancer SurvivorsThe most pressing need is to develop resources for cancer survivors that address their unmet needs and are accessible in terms of literacy. Study findings outline the highest-scoring resources currently available to survivors, families, and clinicians. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - January 10, 2023 Category: Cancer & Oncology Source Type: research
Starting the Conversation: randomized pilot trial of an intervention to promote effective clinical communication about sexual health for gynecologic cancer survivors
ConclusionsData support the STC intervention as feasible and acceptable, with promising effects for gynecologic cancer survivors ’ communication about sexual health concerns. Because sexual health communication is relevant across the treatment trajectory, we included both on-treatment and post-treatment survivors. While this may be a limitation, it could also enhance sample generalizability. A larger trial is needed to dete rmine efficacy.Implications for Cancer SurvivorsCommunication about sexual health is important yet lacking for cancer survivors. Patient-focused interventions may help address concerns and improve sur...
Source: Journal of Cancer Survivorship - January 6, 2023 Category: Cancer & Oncology Source Type: research
Quality of care and quality of life as experienced by patients with advanced cancer of a rare tumour type: results of the multicentre observational eQuiPe study
ConclusionsPatients with advanced rare cancers experience less continuity of care, and the impact of the disease on social and family life seems higher compared to patients with advanced common cancers.Implications for Cancer SurvivorsTo enhance the QoC and QoL of patients with advanced rare cancers, supportive care should mainly focus on improving continuity of care and patients ’ social functioning. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - January 3, 2023 Category: Cancer & Oncology Source Type: research
Association of financial worry with substance use, mental health, and quality of life in cancer patients
ConclusionFinancial worry among cancer survivors is associated with anxiety, depression, and worse quality of life. Of the evaluated substances, there was only an increased odds of current tobacco use with financial worry. Future longitudinal studies should inform the relationships between these factors.Implications for Cancer SurvivorsFinancial worry and material hardship may both need to be addressed in cancer survivorship. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - January 3, 2023 Category: Cancer & Oncology Source Type: research
Quality of life of patients with rare cancer: a comparison with patients with colorectal cancer and the association with disease trajectory-related factors
ConclusionPatients with rare cancers have a lower self-reported QoL than patients with CRC, and several disease trajectory-related factors are associated with QoL in patients with rare cancer.Implications for Cancer SurvivorsTo improve QoL of patients with rare cancer, appropriate guidance and support by healthcare professionals throughout the disease trajectory are needed, as well as early diagnosis and proper referral to centres of expertise. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - December 31, 2022 Category: Cancer & Oncology Source Type: research
Relationship between work performance and quality of life in long-term survivors of pediatric and adolescent hematopoietic cell transplant
Conclusions and Implications for Cancer SurvivorsWe found significant associations between survivors ’ work status, performance, and QOL. Our findings provide an important insight on the implications of work outcomes on HCT survivors’ physical, mental, and social health and emphasize the importance of longitudinal assessment of work status, performance, and QOL. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - December 30, 2022 Category: Cancer & Oncology Source Type: research
Patient-reported needs for coping with worry or fear about cancer recurrence and the extent to which they are being met: a survey study
ConclusionsAlmost all patients who experience FCR have a need for support. Even though most receive some support, several gaps remain.Implications for Cancer SurvivorsMany report an unmet need for psychological help or practical tips about FCR. We recommend for healthcare providers to discuss FCR with patients and inform them about the support available. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - December 30, 2022 Category: Cancer & Oncology Source Type: research
Receipt of follow-up care plans on colorectal cancer screening among breast, prostate, and lung cancer survivors
ConclusionsReceipt of follow-up care plans was associated with greater CRC screening use in breast and prostate cancers. Lung cancer survivors demonstrated lower screening use despite receipt of follow-up care plans.Implication for Cancer SurvivorsPatient and provider communication regarding CRC screening recommendation should be included in their follow-up care plans. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - December 27, 2022 Category: Cancer & Oncology Source Type: research
Use of photo methods in research studies with cancer survivors and their caregivers: a scoping review
ConclusionPhoto methods are most frequently used in order to capture qualitative data in cancer populations; however, there are missed opportunities in their lack of use for intervention and systemic change. In addition, inconsistent reporting of demographics and cancer characteristics limits our ability to synthesize these data across studies. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - December 26, 2022 Category: Cancer & Oncology Source Type: research
Exercise adherence in a randomized controlled trial of exercise on quality of life in ovarian cancer survivors
ConclusionsWomen attending more counseling sessions or with no cancer recurrence during the study were more likely to meet the exercise goal. More research is needed to understand ideal counseling intensity for ovarian cancer survivors.Implications for Cancer SurvivorsEighteen counseling sessions are sufficient for ovarian cancer survivors to achieve 150 min/week exercise. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - December 23, 2022 Category: Cancer & Oncology Source Type: research
Cancer survivors maintain health benefits 6 to 12 months after exercise-based rehabilitation: a systematic review and meta-analysis
ConclusionHealth outcomes of cancer survivors after exercise-based rehabilitation can be maintained after rehabilitation completion.Implications for Cancer SurvivorsCancer survivors can maintain health benefits achieved through exercise-based rehabilitation. (Source: Journal of Cancer Survivorship)
Source: Journal of Cancer Survivorship - December 22, 2022 Category: Cancer & Oncology Source Type: research
