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Exact-matching algorithms using administrative health claims database equivalence factors for real-world data analysis based on the target trial emulation framework
AbstractReal-world data have become increasingly important in medical science and healthcare. A new, effective, and practically feasible statistical design is needed to unlock the potential of real-world data that decision-makers and practitioners can use to meet people ’s healthcare needs. In the first half of the study, we validated our proposed new method by simulation, and in the second half, we conducted a clinical study on actual real-world data. We proposed the “Exact Matching Algorithm Using Administrative Health Claims Database Equivalence Factors (AHC DEFs)” using a target trial emulation framework. The sim...
Source: Health Services and Outcomes Research Methodology - February 2, 2024 Category: Statistics Source Type: research

Blockchain based E-procurement system in healthcare
AbstractPublic procurement, a critical facet in acquiring goods and services, has garnered scholarly attention in e-procurement. However, its application in healthcare remains underexplored. This paper addresses this gap by proposing a decentralized blockchain-based e-procurement system in healthcare (B-ePS) to enhance transparency, reliability, and security. The study leverages the Ethereum blockchain and smart contracts to establish B-ePS, aiming to mitigate traditional e-procurement concerns. By emphasizing the blockchain's non-tampering characteristics, information traceability, and decentralization, the authors contri...
Source: Health Services and Outcomes Research Methodology - January 24, 2024 Category: Statistics Source Type: research

ATRAcTR (Authentic Transparent Relevant Accurate Track-Record): a screening tool to assess the potential for real-world data sources to support creation of credible real-world evidence for regulatory decision-making
AbstractAdoption and use of real-world data (RWD) for decision-making has been complicated by concerns regarding whether RWD was fit-for-purpose or was of sufficient validity to support the creation of credible RWE. This has greater urgency as regulatory agencies begin to use real world evidence (RWE) to inform decisions about treatment effectiveness. Researchers need an efficient and systematic method to screen the quality of RWD sources considered for use in studies of effectiveness and safety. Based on a literature review we developed a listing of screening criteria that have been previously proposed to assess the quali...
Source: Health Services and Outcomes Research Methodology - November 29, 2023 Category: Statistics Source Type: research

Evaluation of survey delivery methods in a national study of Veteran ’s healthcare preferences
We describe two recruitment strategies offering concurrent online, paper, and phone survey options to different sets of participants and examine response and missingness p atterns between recruitment methods and modalities. In Strategy 1 we sent recruitment letters presenting options to complete our survey online or on paper. If patients indicated that they wanted to complete a paper survey, we mailed them a paper survey. In Strategy 2 we sent recruitment letters with paper surveys and included the option to complete the survey online. We compared response rates, characteristics, and missingness for the strategies and surv...
Source: Health Services and Outcomes Research Methodology - November 28, 2023 Category: Statistics Source Type: research

Propensity score weighting with survey weighted data when outcomes are binary: a simulation study
AbstractPropensity score methods have been widely adopted in observational studies, however research on propensity score-based weighting (PSW) methods in complex survey data settings is lacking, particularly for binary outcomes. We conducted a simulation study to compare eight propensity score weighting approaches for estimating treatment effects using survey  weighted data. Each of the eight methods is applied to estimation of two measures of the population-level treatment effect: the population average treatment effect (PATE), and the population average treatment effect on the treated (PATT). The methods are compared in...
Source: Health Services and Outcomes Research Methodology - November 18, 2023 Category: Statistics Source Type: research

Bootstrap approach to disparity testing with source uncertainty in the data
This article addresses the problem of one-sided hypothesis testing on the means of two populations when there is uncertainty as to which population a datum is drawn. Such situations arise, for example, in the use of Bayesian imputation methods to assess racial and ethnic disparities with certain survey, health, and financial data. Earlier work on this problem, from a frequentist point of view, is limited in the sample sizes for which computations could reasonably be executed. By employing a bootstrap approach to generate summary statistics for the population ofp-values arising from all possible configurations of the data, ...
Source: Health Services and Outcomes Research Methodology - November 13, 2023 Category: Statistics Source Type: research

Descriptive and inferential analysis of features for Dysphonia and Dysarthria Parkinson ’s disease symptoms
AbstractParkinson ’s disease is related to nervous system disorders in human beings. In this paper, the status of Parkinson’s disease has been predicted based on the analysis of features of two Parkinson’s disease symptoms: Dysphonia and Dysarthria. The Dysphonia symptom has been measured by analyzing the featu res extracted from the vocal sounds of a patient. The Dysarthria symptom of Parkinson’s disease has been analyzed by the features extracted from the speech signals of a patient. Hence, two different prediction models have been built for deriving the status of Parkinson’s disease. The derivation of these pr...
Source: Health Services and Outcomes Research Methodology - November 1, 2023 Category: Statistics Source Type: research

Inspecting the quality of care: a comparison of CUSUM methods for inter hospital performance
AbstractDuring the past 14 years, a clinical audit has been used in the Netherlands to provide hospitals with data on their performance in colorectal cancer care. Continuous feedback on the quality of care provided at each hospital is essential to improve patient outcomes. It is unclear which methods should be used to generate most informative output for the identification of potential quality issues. Our aim is to compare the commonly employed funnel plot with existing cumulative sum (CUSUM) methodology for the evaluation of postoperative survival and hospital stay outcomes of patients who underwent colorectal surgery in ...
Source: Health Services and Outcomes Research Methodology - October 24, 2023 Category: Statistics Source Type: research