Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
Calibration of the comet assay using ionising radiation
Mutat Res Genet Toxicol Environ Mutagen. 2023 Jan;885:503560. doi: 10.1016/j.mrgentox.2022.503560. Epub 2022 Nov 17.ABSTRACTSeveral trials have attempted to identify sources of inter-laboratory variability in comet assay results, aiming at achieving more equal responses. Ionising radiation induces a defined level of DNA single-strand breaks (per dose/base pairs) and is used as a reference when comparing comet results but relies on accurately determined radiation doses. In this ring test we studied the significance of dose calibrations and comet assay protocol differences, with the object of identifying causes of variabilit...
Source: Genetics and Molecular Research - January 20, 2023 Category: Genetics & Stem Cells Authors: Gunnar Brunborg Dag M Eide Anne Graupner Kristine Gutzkow Sergey Shaposhnikov Marcin Kruszewski Nikolai Sirota George D D Jones Gudrun Koppen Filip Vanhavere Peter M øller Rudolf Stetina Hildegunn Dahl Andrew Collins Source Type: research
