Head and Neck Imaging
AbstractNeuroimaging techniques play a central role in the diagnosis and management of Central nervous system (CNS) diseases. The use of Magnetic Resonance Imaging (MRI) has helped to diagnose and understand disease processes early on. The use of contrast media has improved visualization of normal and abnormal tissues. New developments in contrasat media agents have shown great promise: Goadobutrol, the first one molar paramagnetic contrast agent has shown to be of use in MR angiography and in perfusion of the brain while newer applications such as to the diagnosis of inflammatory diseases such as multiple sclerosis are pr...
Source: European Radiology Supplements - August 28, 2009 Category: Radiology Source Type: research

Venous MR imaging with blood pool agents
AbstractBlood pool contrast agents such as Gadofosveset trisodium (Vasovist ®, Bayer Schering Pharma AG, Berlin, Germany) are making MRA a viable first-line imaging modality for a variety of patients with venous disorders. They allow extended imaging and multiple acquisitions without loss of resolution with a single low-dose injection. The methodology is robust and can be adjusted to the patient without causing workflow problems. The emphasis of this article is on the venous applications of the blood pool contrast agent Vasovist® including venous visualisation to plan surgical and interventional procedures and venous thr...
Source: European Radiology Supplements - August 28, 2009 Category: Radiology Source Type: research

State-of-the-art MRI with blood pool agents: new perspectives for advanced vascular imaging
(Source: European Radiology Supplements)
Source: European Radiology Supplements - August 28, 2009 Category: Radiology Source Type: research

Peripheral vascular imaging with a blood pool contrast agent: imaging strategies and influence on patient management
We describe the advantages of high resolution steady state imaging and provide recent clinical results of this new imaging tool which shows improved diagnostic accuracy of steady-state imaging compared to first-pass imaging and DSA as the reference standard and impact on patient management. (Source: European Radiology Supplements)
Source: European Radiology Supplements - August 28, 2009 Category: Radiology Source Type: research

Summary of the safety data for Gadobutrol and Gadofosveset
AbstractDespite the differences in imaging conditions and the range of approved indications for gadolinium-based contrast agents, the similarities in the structures of these substances have so far resulted in largely similar safety profiles. Nevertheless, some safety-related questions have been raised recently, which indicates that the existing differences in the physicochemical and pharmacokinetic properties of these contrast agents may result in differences in some aspects of the safety profile, in particular for special populations under particular circumstances. An analysis of the current data shows that Gadobutrol and...
Source: European Radiology Supplements - August 28, 2009 Category: Radiology Source Type: research

MRA of the foot with a blood pool agent
AbstractFoot complications associated with diabetes are the most common cause of non-traumatic lower-extremity amputations in the industrialised countries. Revascularisation techniques require precise preoperative imaging. Magnetic resonance angiography (MRA) using gadofosveset trisodium (Vasovist, Bayer Schering Pharma AG, Berlin, Germany) has the potential to detect significantly more patent pedal vessel segments than selective digital substractive angiography (DSA) in an examination with two blinded readers. MRI and MRA are the imaging methods of choice for differentiated assessment of the diabetic foot and its complica...
Source: European Radiology Supplements - August 28, 2009 Category: Radiology Source Type: research

Venous MR imaging with blood pool agents
AbstractBlood pool contrast agents such as Gadofosveset trisodium (Vasovist ®, Bayer Schering Pharma AG, Berlin, Germany) are making MRA a viable first-line imaging modality for a variety of patients with venous disorders. They allow extended imaging and multiple acquisitions without loss of resolution with a single low-dose injection. The methodology is robust and can be adjusted to the patient without causing workflow problems. The emphasis of this article is on the venous applications of the blood pool contrast agent Vasovist® including venous visualisation to plan surgical and interventional procedures and venous thr...
Source: European Radiology Supplements - August 28, 2009 Category: Radiology Source Type: research

State-of-the-art MRI with blood pool agents: new perspectives for advanced vascular imaging
(Source: European Radiology Supplements)
Source: European Radiology Supplements - August 28, 2009 Category: Radiology Source Type: research

Peripheral vascular imaging with a blood pool contrast agent: imaging strategies and influence on patient management
We describe the advantages of high resolution steady state imaging and provide recent clinical results of this new imaging tool which shows improved diagnostic accuracy of steady-state imaging compared to first-pass imaging and DSA as the reference standard and impact on patient management. (Source: European Radiology Supplements)
Source: European Radiology Supplements - August 28, 2009 Category: Radiology Source Type: research

Summary of the safety data for Gadobutrol and Gadofosveset
AbstractDespite the differences in imaging conditions and the range of approved indications for gadolinium-based contrast agents, the similarities in the structures of these substances have so far resulted in largely similar safety profiles. Nevertheless, some safety-related questions have been raised recently, which indicates that the existing differences in the physicochemical and pharmacokinetic properties of these contrast agents may result in differences in some aspects of the safety profile, in particular for special populations under particular circumstances. An analysis of the current data shows that Gadobutrol and...
Source: European Radiology Supplements - August 28, 2009 Category: Radiology Source Type: research

MRA of the foot with a blood pool agent
AbstractFoot complications associated with diabetes are the most common cause of non-traumatic lower-extremity amputations in the industrialised countries. Revascularisation techniques require precise preoperative imaging. Magnetic resonance angiography (MRA) using gadofosveset trisodium (Vasovist, Bayer Schering Pharma AG, Berlin, Germany) has the potential to detect significantly more patent pedal vessel segments than selective digital substractive angiography (DSA) in an examination with two blinded readers. MRI and MRA are the imaging methods of choice for differentiated assessment of the diabetic foot and its complica...
Source: European Radiology Supplements - August 28, 2009 Category: Radiology Source Type: research

Head and Neck Imaging
AbstractNeuroimaging techniques play a central role in the diagnosis and management of Central nervous system (CNS) diseases. The use of Magnetic Resonance Imaging (MRI) has helped to diagnose and understand disease processes early on. The use of contrast media has improved visualization of normal and abnormal tissues. New developments in contrasat media agents have shown great promise: Goadobutrol, the first one molar paramagnetic contrast agent has shown to be of use in MR angiography and in perfusion of the brain while newer applications such as to the diagnosis of inflammatory diseases such as multiple sclerosis are pr...
Source: European Radiology Supplements - August 28, 2009 Category: Radiology Source Type: research

Abdominal MR Angiography with blood pool agents
AbstractAbdominal MR Angiography is an important tool in clinical practice with proven diagnostic accuracy for a variety of indications. The recent introduction of the blood pool agent Vasovist makes it possible to further improve image quality of first-pass MR angiography. In addition, Vasovist enables study of the venous system with unprecedented clarity and study of renal perfusion (Source: European Radiology Supplements)
Source: European Radiology Supplements - December 1, 2008 Category: Radiology Source Type: research

Venous MR imaging with blood pool agents
Abstract Blood pool contrast agents such as Gadofosveset trisodium (Vasovist®, Bayer Schering Pharma AG, Berlin, Germany) are making MRA a viable first-line imaging modality for a variety of patients with venous disorders. They allow extended imaging and multiple acquisitions without loss of resolution with a single low-dose injection. The methodology is robust and can be adjusted to the patient without causing workflow problems. The emphasis of this article is on the venous applications of the blood pool contrast agent Vasovist® including venous visualisation to plan surgical and interventional proce...
Source: European Radiology Supplements - December 1, 2008 Category: Radiology Source Type: research