SGLT2i relieve proteinuria in diabetic nephropathy patients potentially by inhibiting renal oxidative stress rather than through AGEs pathway
To estimate the effects of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) on proteinuria and oxidative stress expression in type 2 diabetes patients. (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 16, 2024 Category: Endocrinology Authors: Xiao-chun Zeng, Yuan Tian, Xian-ming Liang, Xiao-bin Wu, Chun-meng Yao and Xiao-min Chen Tags: Research Source Type: research

Clinical inertia in newly diagnosed type 2 diabetes mellitus among patients attending selected healthcare institutions in Colombia
The burden of disease of diabetes in Colombia have increased in the last decades. Secondary prevention is crucial for diabetes control. Many patients already treated remain with poor glycemic control and witho... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 15, 2024 Category: Endocrinology Authors: Nelson Alvis-Guzman, Mart ín Romero, Fernando Salcedo-Mejia, Maria Carrasquilla-Sotomayor, Lina Gómez, Mónica María Rojas, Juan Camilo Urrego, Claudia Catalina Beltrán, Jaime Enrique Ruíz, Adriana Velásquez, Juan Carlos Orengo and Adolfo Pinzón Tags: Research Source Type: research

Global trends and developments in mindfulness interventions for diabetes: a bibliometric study
Diabetes is a metabolic disorder posing a global threat to health. Many scholars are dedicated to developing non-pharmacological therapies, and mindfulness intervention is among the potentially effective appro... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 15, 2024 Category: Endocrinology Authors: Sijia Jiang, Xiaoli Pan, Hansen Li and Yuqin Su Tags: Research Source Type: research

Stress-induced hyperglycemia is associated with the mortality of thrombotic thrombocytopenic purpura patients
Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy with a rapid progression and high mortality rate. We aimed to explore early risk factors for mortality in patients with TTP. (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 15, 2024 Category: Endocrinology Authors: Lingling Hu, Jing Wang, Xiaxia Jin, Guoguang Lu, Meidan Fang, Jian Shen, Tao-Hsin Tung and Bo Shen Tags: Research Source Type: research

The intervention of cannabinoid receptor in chronic and acute kidney disease animal models: a systematic review and meta-analysis
Cannabinoid receptors are components of the endocannabinoid system that affect various physiological functions. We aim to investigate the effect of cannabinoid receptor modulation on kidney disease. (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 15, 2024 Category: Endocrinology Authors: Zihao Zhao, Qianqian Yan, Junwei Xie, Zhenjie Liu, Fengxun Liu, Yong Liu, Sijie Zhou, Shaokang Pan, Dongwei Liu, Jiayu Duan and Zhangsuo Liu Tags: Review Source Type: research

Early signs of myocardial systolic dysfunction in patients with type 2 diabetes are strongly associated with myocardial microvascular dysfunction independent of myocardial fibrosis: a prospective cohort study
Patients with diabetes demonstrate early left ventricular systolic dysfunction. Notably reduced global longitudinal strain (GLS) is related to poor outcomes, the underlying pathophysiology is however still not... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 13, 2024 Category: Endocrinology Authors: Annemie S. Bojer, Martin H. S ørensen, Stine H. Madsen, David A. Broadbent, Sven Plein, Peter Gæde and Per L. Madsen Tags: Research Source Type: research

Sacubitril/valsartan ameliorates tubulointerstitial fibrosis by restoring mitochondrial homeostasis in diabetic kidney disease
Tubulointerstitial fibrosis plays an important role in the progression of diabetic kidney disease (DKD). Sacubitril/valsartan (Sac/Val) exerts a robust beneficial effect in DKD. However, the potential function... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 10, 2024 Category: Endocrinology Authors: Xing-Jian Zhang, Cong-Cong Liu, Zuo-Lin Li, Lin Ding, Yan Zhou, Dong-Jie Zhang, Yao Zhang, Shu-Ting Hou and Rui-Xia Ma Tags: Research Source Type: research

Pancreatic enzyme replacement therapy in subjects with exocrine pancreatic insufficiency and diabetes mellitus: a real-life, case –control study
Exocrine pancreatic insufficiency (EPI) can be associated with all types of diabetes. Pancreatic enzyme replacement therapy (PERT) has short and long-term benefits in subjects with EPI, but its effects on diab... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 9, 2024 Category: Endocrinology Authors: Laure Alexandre-Heymann, Fetta Yaker, Pierre Bel Lassen, Dani èle Dubois-Laforgue and Etienne Larger Tags: Research Source Type: research

Correction: The interrelationship and accumulation of cardiometabolic risk factors amongst young adults in the United Arab Emirates: The UAE Healthy Future Study
(Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 7, 2024 Category: Endocrinology Authors: Fatima Mezhal, Abderrahim Oulhaj, Abdishakur Abdulle, Abdulla AlJunaibi, Abdulla Alnaeemi, Amar Ahmad, Andrea Leinberger ‑Jabari, Ayesha S. Al Dhaheri, E. Murat Tuzcu, Eiman AlZaabi, Fatma Al‑Maskari, Fatme Alanouti, Fayza Alameri, Habiba Alsafar, Ham Tags: Correction Source Type: research

Exosomes derived from BMSCs enhance diabetic wound healing through circ-Snhg11 delivery
Exosomes (Exos) generated from bone mesenchymal stem cells (BMSCs) are elucidated to enhance cutaneous wound healing in mice models of diabetes mellitus (DM). While underlying mechanisms remain unknown. (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 7, 2024 Category: Endocrinology Authors: Tao Tang, Linyi Chen, Ming Zhang, Chuang Wang, Xiaolong Du, Shenglin Ye, Xiaoqiang Li, Hong Chen and Nan Hu Tags: Research Source Type: research

Dapagliflozin improves podocytes injury in diabetic nephropathy via regulating cholesterol balance through KLF5 targeting the ABCA1 signalling pathway
Diabetic nephropathy (DN), one of the more prevalent microvascular complications in patients diagnosed with diabetes mellitus, is attributed as the main cause of end-stage renal disease (ESRD). Lipotoxicity in... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 7, 2024 Category: Endocrinology Authors: Jingshu Sun, Xinyu Zhang, Simeng Wang, Dandan Chen, Jianqiang Shu, Nannan Chong, Qinglian Wang and Ying Xu Tags: Research Source Type: research

Long noncoding RNA XIST promotes cell proliferation and migration in diabetic foot ulcers through the miR-126-3p/EGFR axis
The prevalence of diabetic foot ulcers (DFUs) has caused serious harm to human health. To date, a highly effective treatment is lacking. Long noncoding RNA X-inactive specific transcript (lncRNA XIST) has been... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 6, 2024 Category: Endocrinology Authors: Wangbing Hong, Zhenfang Xiong, Xin Wang, Xincheng Liao, Mingzhuo Liu, Zhengying Jiang, Dinghong Min, Jiaqi Li, Guanghua Guo and Zhonghua Fu Tags: Research Source Type: research

Leptin receptor deficiency impedes metabolic surgery related-weight loss through inhibition of energy expenditure in db/db mice
Roux-en-Y gastric bypass (RYGB) surgery is an effective metabolic surgery against diabetes and obesity. Clinical evidence indicates that patients with severe obesity have a poor curative effect in losing weigh... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 1, 2024 Category: Endocrinology Authors: Dan Tong, Jie Xiang, Wei Liu, Fang Sun, Lijuan Wang, Aidi Mou, Tingbing Cao, Qing Zhou, Mei You, Yingying Liao, Peng Gao, Daoyan Liu, Zongshi Lu and Zhiming Zhu Tags: Research Source Type: research

Current and past depression as risk factors for incident type 2 diabetes mellitus and pre-diabetes in men and women: evidence from a longitudinal community cohort
Depression is associated with an increased risk for type 2 diabetes mellitus. However, depression may take different courses, and it is not fully understood how these affect the development of diabetes. It is ... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - February 1, 2024 Category: Endocrinology Authors: Felix S. Wicke, Dani ëlle Otten, Andreas Schulz, Philipp S. Wild, Karl J. Lackner, Thomas Münzel, Jochem König, Mareike Ernst, Jörg Wiltink, Iris Reiner, Jasmin Ghaemi Kerahrodi, Norbert Pfeiffer and Manfred E. Beutel Tags: Research Source Type: research

An elevated urinary albumin-to-creatinine ratio increases the risk of incident cardia-cerebrovascular disease in individuals with type 2 diabetes
We aimed to explore the associations between urine albumin-to-creatinine ratio (uACR) and cardia-cerebrovascular disease (CVD) in Chinese population with type 2 diabetes(T2D). (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - January 31, 2024 Category: Endocrinology Authors: Jie Tao, Dasen Sang, Xinxin Zhang, Xin Liu, Guodong Wang, Shuohua Chen, Shouling Wu and Wei Geng Tags: Research Source Type: research