Sleep in intensive care units
Abstract
Patients admitted to intensive care units (ICU) have significantly disrupted sleep with circadian displacement. In this article we briefly discuss factors related to sleep disruption in ICU and the tasks of individual members of ICU multidisciplinary teams in promoting consolidated nocturnal sleep of critically ill patients. (Source: Current Respiratory Care Reports)
Source: Current Respiratory Care Reports - June 1, 2014 Category: Respiratory Medicine Source Type: research
Immunotherapy for non-small-cell lung cancer: current approaches
Abstract
Lung cancer has long been regarded as a poor candidate for immunotherapy, because it has a relatively low content of tumor-infiltrating lymphocytes compared with, for example, melanoma. However, new developments in immunotherapy are about to change this situation. Therapeutic vaccines are different from the well-known prophylactic vaccines, in that they are designed to treat patients already suffering from a disease instead of preventing the disease in healthy individuals. Several therapeutic vaccines are in late-stage clinical development for non-small-cell lung cancer (NSCLC). These vaccines ...
Source: Current Respiratory Care Reports - March 1, 2014 Category: Respiratory Medicine Source Type: research
Transbronchial cryobiopsy in diffuse lung disease
Abstract
Transbronchial biopsy is required for evaluation of some patients with interstitial lung disease (ILD). The diagnostic success of histopathologic assessment is variable, and affected by such factors as specimen size and the presence of crush artifact attributable to the use of conventional biopsy forceps. Use of cryoprobes to perform transbronchial biopsy enables larger and better quality samples to be obtained compared with conventional methods. The safety profile of transbronchial cryobiopsy is similar to that of transbronchial biopsy with forceps. Diagnostic success of histopathology seems h...
Source: Current Respiratory Care Reports - March 1, 2014 Category: Respiratory Medicine Source Type: research
Optical coherence tomography of the airways
Abstract
Optical coherence tomography (OCT) is a high-resolution imaging modality that uses near infrared light reflected from the tissue optical interfaces to generate real-time images with near-histology resolution. Bronchoscopic use of OCT has potential applications in the study, diagnosis, monitoring, and treatment of asthma, COPD, and histologically benign and malignant central airway disorders. This paper provides an overview of the rationale and principles of OCT imaging, describes the limitations of current technology, and summarizes potential future developments that may overcome the existing c...
Source: Current Respiratory Care Reports - March 1, 2014 Category: Respiratory Medicine Source Type: research
