Gender Minority Stress, Psychiatric Comorbidities, and the Experience of Migraine in Transgender and Gender-Diverse Individuals: a Narrative Review
AbstractPurpose of ReviewThis review aims to discuss the experience of migraine in transgender and gender-diverse individuals as it relates to other psychiatric comorbidities such as anxiety, depression, PTSD, and others. As this population faces stigma and discrimination, literature posits that gender minority stress can also contribute to the experience of pain in these individuals.Recent FindingsThough there is little explicit data on these topics, more recent studies have explored the concept of gender minority stress and how stigma and discrimination can affect health outcomes and overall perception of health. These f...
Source: Current Pain and Headache Reports - December 15, 2021 Category: Neurology Source Type: research

Neurostimulation Treatment in Chronic Cluster Headache —a Narrative Review
AbstractPurpose of ReviewIn this narrative review, the current literature on neurostimulation methods in the treatment of chronic cluster headache is evaluated. These neurostimulation methods include deep brain stimulation, vagus nerve stimulation, greater occipital nerve stimulation, sphenopalatine ganglion stimulation, transcranial magnetic stimulation, transcranial direct current stimulation, supraorbital nerve stimulation, and cervical spinal cord stimulation.Recent FindingsAltogether, only nVNS and SPG stimulation are supported by at least one positive sham-controlled clinical trial for preventive and acute attack (on...
Source: Current Pain and Headache Reports - December 11, 2021 Category: Neurology Source Type: research

Non-pharmacologic and Mindful-Based Approaches for Pediatric Headache Disorders: a Review
AbstractPurpose of ReviewHeadache disorders in children and adolescents are common. Among the different headache disorders, migraine and tension headache are highly prevalent and often debilitating. Pharmacological treatments for pediatric patients are often not approved or effective. Practice guidelines for prevention of pediatric headache and migraine are now incorporating information and recommendations regarding non-pharmacologic therapeutic options. Understanding the mechanism of action, safety, and efficacy of the non-pharmacologic as well as mindful-based therapeutic alternatives currently available for the manageme...
Source: Current Pain and Headache Reports - December 11, 2021 Category: Neurology Source Type: research

Updates in the Diagnostic Approach of Headache
AbstractPurpose of ReviewIn this review, we summarize updates in the diagnostic approach of headaches with the aim of facilitating the distinction between primary and secondary etiology in headaches.Recent FindingsIn the USA, headache is the fifth most common complaint in the emergency department, but only a minority will have a secondary etiology. Initial suspicion and diagnostic workup of secondary headache relies on a patient ’s medical history due to a scarcity of validated biomarkers. A special interest group under theInternational Headache Society recently synthesized information on red flags (information that indi...
Source: Current Pain and Headache Reports - December 11, 2021 Category: Neurology Source Type: research

Beyond the Raskin Protocol: Ketamine, Lidocaine, and Other Therapies for Refractory Chronic  Migraine
AbstractPurpose of ReviewThe purpose of this review is to discuss the available evidence and therapeutic considerations for intravenous drug therapy for refractory chronic migraine.Recent FindingsIn carefully monitored settings, the inpatient administration of intravenous lidocaine and ketamine can be successful in treating refractory chronic migraine.SummaryMany patients with refractory chronic migraine have experienced treatment failure with the Raskin protocol. The use of aggressive inpatient infusion therapy consisting of intravenous lidocaine or ketamine, along with other adjunctive medications, has become increasingl...
Source: Current Pain and Headache Reports - December 11, 2021 Category: Neurology Source Type: research

Intrathecal Baclofen Monotherapy and Polyanalgesia for Treating Chronic Pain in Patients with Severe Spasticity
AbstractPurpose of ReviewIntrathecal drug delivery is a well evidenced strategy for the treatment of many chronic pain syndromes. While opioids, anesthetics, and ziconotide are the most commonly used agents, intrathecal baclofen (ITB), which is indicated to treat spasticity, is also thought to have some analgesic properties that are poorly understood. These analgesic benefits have been reported with ITB use in treating patients with central neurological disorders who suffer from severe spasticity and chronic pain. Our review aims to characterize ITB ’s effects on pain, function, and quality of life in patients with sever...
Source: Current Pain and Headache Reports - December 11, 2021 Category: Neurology Source Type: research

Effect of Guided Imagery on Pain and Health-Related Quality of Life in Musculoskeletal Medicine: a Comprehensive Narrative Review
AbstractPurpose of ReviewGuided imagery (GI) is a non-pharmacological method used to reduce pain, stress, and anxiety. No comprehensive review has yet investigated the application of GI in musculoskeletal medicine, its various types, and potential mechanisms. The aim of this comprehensive narrative review was to examine the types of GI used in musculoskeletal medicine and GI effect on pain and health-related quality of life.Recent FindingsA comprehensive narrative review of the English language scientific literature. PubMed, Google Scholar, ProQuest, and PEDro databases were searched from inception until August 2020 using ...
Source: Current Pain and Headache Reports - December 11, 2021 Category: Neurology Source Type: research

Stigma and Migraine: Developing Effective Interventions
AbstractPurpose of ReviewMigraine and other primary headache disorders do not receive adequate research funding, medical resources, or other forms of structural support relative to their prevalence and the disability they cause. In recent research, scholars have argued that stigma associated with headache disorders explains some of this discrepancy.This review will discuss (1) the factors contributing to stigma toward migraine and other primary headache disorders, (2) how structural and enacted stigma may perpetuate individual disability, (3) the impact of internalized stigma, and (4) interventions to mitigate stigma towar...
Source: Current Pain and Headache Reports - December 6, 2021 Category: Neurology Source Type: research

Correction to: A Review of Techniques of Intercostal Nerve Blocks
(Source: Current Pain and Headache Reports)
Source: Current Pain and Headache Reports - November 27, 2021 Category: Neurology Source Type: research

Co-Occurring Trauma and Non-Suicidal Self-Injury Among People With Chronic Pain: A Systematic Review
AbstractPurpose of ReviewTrauma and posttraumatic stress are common among individuals with chronic pain and contribute to increased morbidity and impairment. Individuals with trauma and chronic pain may be prone to non-suicidal self-injury, a relatively common yet risky self-regulatory behavior. There is a dearth of research on the intersection of trauma, chronic pain, and non-suicidal self-injury (NSSI). We conducted a systematic review of the extant literature.Recent FindingsFive quantitative and eight case reports were identified. Only one quantitative study reported specifically on NSSI. Self-harm rates varied across s...
Source: Current Pain and Headache Reports - November 11, 2021 Category: Neurology Source Type: research

Update of Neuromodulation in Chronic Migraine
AbstractPurpose of ReviewNeuromodulation devices have become an attractive alternative to traditional pharmacotherapy for migraine, especially for patients intolerant to medication or who prefer non-pharmacological options. In the past decades, many studies demonstrated the efficacy of neuromodulation devices in patients with episodic migraine (EM). However, the benefit of these devices on chronic migraine (CM), which is typically more debilitating and refractory than EM, remains not well studied.Recent FindingsWe reviewed the literature within the last five  years on using FDA-cleared and investigational devices for CM. ...
Source: Current Pain and Headache Reports - November 11, 2021 Category: Neurology Source Type: research

The Psychiatric Comorbidities of Migraine in Children and Adolescents
AbstractPurpose of ReviewUnderstanding comorbidities in migraine is important because it can help us understand disease pathophysiology while also aiding the development of more effective treatment strategies. Additionally, it can provide greater awareness about appropriate diagnosis, the need for additional disease screening, and the natural history of migraine. Psychiatric comorbidities have been independently studied in both adults and children with migraine because their presentations can be distinct, and the physiology in these two groups can be different.Recent FindingsWhile symptoms of anxiety and depression seem to...
Source: Current Pain and Headache Reports - November 11, 2021 Category: Neurology Source Type: research

Headache as a Symptom of COVID-19: Narrative Review of 1-Year Research
AbstractPurpose of ReviewHeadache is a common symptom of COVID-19 with emerging literature being published on the subject. Although it may seem unspecific, scientific evidence has allowed a better definition of this headache type, revealing relevant associations with other COVID-19 symptoms and prognoses. We therefore sought to highlight the most remarkable findings concerning headache secondary to COVID-19, specifically focusing on epidemiology, characteristics, pathophysiology, and treatments.Recent FindingsThe real prevalence of headache as a symptom of COVID-19 is still unclear ranging from 10 to 70%. Headache mainly h...
Source: Current Pain and Headache Reports - November 11, 2021 Category: Neurology Source Type: research

Indomethacin-Induced Headache: Causing the Problem You Are Trying to Solve
AbstractPurpose of ReviewIndomethacin is an important medication in the headache medicine toolbox given its utility for both of the diagnosis and treatment of several primary headache disorders. Despite its prevalence in earlier rheumatologic studies, the possibility of drug-induced headache is a not commonly discussed in headache literature.Recent FindingsHerein, we describe a case of drug-induced headache after indomethacin trial for the treatment of an undifferentiated trigeminal autonomic cephalgia.SummaryRecognition of indomethacin-induced headache has important implications for patient education and interpreting the ...
Source: Current Pain and Headache Reports - November 11, 2021 Category: Neurology Source Type: research

Correction to: Reducing New Persistent Opioid Use After Surgery: a Review of Interventions
(Source: Current Pain and Headache Reports)
Source: Current Pain and Headache Reports - November 5, 2021 Category: Neurology Source Type: research