Clinical Schizophrenia and Related Psychoses This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Prevalence and clinical impact of childhood adversities in women with schizophrenia.
Authors: Prokopez CR, Cesoni OM, Caporusso GB, Reffino-Pereyra ML, Alberio G, Vallejos M Abstract Patients with schizophrenia have higher rates of adverse childhood experiences (ACEs) than the general population, and those who suffered multiple traumatic experiences have a higher prevalence of positive symptoms, poorer social functioning and more suicidal ideations and behavior. The current study aims to determine the prevalence of ACEs in a female patient sample with schizophrenia. An observational descriptive cross-sectional study was conducted. Participants included 50 female patients older than 18 year...
Source: Clinical Schizophrenia and Related Psychoses - June 28, 2018 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

When Dementia Kills Before One Passes Away: Case Report of Cotard's Syndrome.
Authors: Pereira CW, Florentino ISM, Machado L Abstract INTRODUCTION: Cotard's Syndrome (CS), among the noncognitive changes in the forms of dementia, is a seldom-found manifestation (1). This syndrome is characterized by the delusion of having lost organs (the individual experiences huge changes in the body and believes that he/she no longer has one or more organs) and by nihilistic delusion (the individual believes he/she or everyone in the world has died or been destroyed) (2). In 1880, Jules Cotard (1840-1889) described a clinical condition that he believed corresponded to a new subtype of depression, ...
Source: Clinical Schizophrenia and Related Psychoses - June 28, 2018 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

Subjectivity and Catatonic Symptoms.
Authors: Clarke C Abstract Although recognized as a feature of schizophrenia since the time of Kraepelin, motor disorders have received relatively little attention, particularly as regard their phenomenology. This is particularly the case in the English-speaking literature, where 'automaticity', mutism, and autonomic instability, have been emphasized among the features of catatonia at the expense of more complex behaviors and mannerisms. The possible relationship between the content of thinking disorders, such as hallucinations and dereistic thinking, and involuntary and semi-voluntary movement disorders, ...
Source: Clinical Schizophrenia and Related Psychoses - June 28, 2018 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

Exploring construct validity of clinical staging in schizophrenia spectrum disorders in an acute psychiatric ward.
CONCLUSION: this study demonstrates that clinical staging in schizophrenia spectrum disorders has an acceptable construct validity between earlier and more chronic stages of disease. Several clinical profilers increase in more advanced stages compared to earlier clinical stages, which supports construct validity. PMID: 29944422 [PubMed - as supplied by publisher] (Source: Clinical Schizophrenia and Related Psychoses)
Source: Clinical Schizophrenia and Related Psychoses - June 28, 2018 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

Psychiatric patient with Chilaiditi's syndrome.
CONCLUSIONS: The diagnosis of the syndrome is vital in order to avoid unnecessary and dangerous surgical interventions. Only few publications of a Chilaiditi syndrome in patients with psychosis are cited in the literature. PMID: 29944423 [PubMed - as supplied by publisher] (Source: Clinical Schizophrenia and Related Psychoses)
Source: Clinical Schizophrenia and Related Psychoses - June 28, 2018 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

Clinical News.
Authors: Buckley PF PMID: 29630410 [PubMed - in process] (Source: Clinical Schizophrenia and Related Psychoses)
Source: Clinical Schizophrenia and Related Psychoses - April 11, 2018 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

From the desk of Peter F. Buckley, MD.
Authors: Buckley PF PMID: 29341819 [PubMed - in process] (Source: Clinical Schizophrenia and Related Psychoses)
Source: Clinical Schizophrenia and Related Psychoses - January 18, 2018 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

Comments on Abilify MyCite.
Authors: Kane JM PMID: 29341820 [PubMed - in process] (Source: Clinical Schizophrenia and Related Psychoses)
Source: Clinical Schizophrenia and Related Psychoses - January 18, 2018 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

Deuterium Tetrabenazine for Tardive Dyskinesia.
Authors: Cummings MA, Proctor GJ, Stahl SM Abstract Tardive dyskinesia remains a significant, potentially stigmatizing or crippling adverse effect for any patient treated with an antipsychotic medication. While second- and third-generation antipsychotics have exhibited lower annual incidence rates for tardive dyskinesia than classic or first-generation agents, 3.9% versus 5.5%, the estimated incidence rate is only modestly lower. When coupled with the fact that second- and third-generation antipsychotic medications have come to be employed in treating a wider range of disorders (e.g., autism spectrum disor...
Source: Clinical Schizophrenia and Related Psychoses - January 18, 2018 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

Aripiprazole Long-Acting Injectable for Maintenance Treatment of Bipolar I Disorder in Adults.
Authors: Aggarwal A, Schrimpf L, Lauriello J Abstract Bipolar I disorder is a serious and disabling psychiatric illness. It is associated with a significant reduction in quality of life and an increased risk for suicide. Pharmacotherapy is essential for both the acute and maintenance treatment of bi-polar I disorder. While multiple oral medications are recommended for the maintenance treatment, there are not many long-acting injectable medications approved for this indication. New treatments that would improve patient adherence have the potential for decreasing relapses and improving patients' ability to r...
Source: Clinical Schizophrenia and Related Psychoses - January 18, 2018 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

Clinical News.
Authors: Buckley PF PMID: 29341823 [PubMed - in process] (Source: Clinical Schizophrenia and Related Psychoses)
Source: Clinical Schizophrenia and Related Psychoses - January 18, 2018 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

A Case of a Patient with Residual Symptoms of Schizophrenia who Relapsed Following Treatment with the Topical Corticosteroid, Clobetasol: A Review of its Risk of Systemic Absorption and Possibility of Exacerbating Psychosis.
We present a case of a patient with schizophrenia who developed morphea. She was liberally treated with the potent topical corticosteroid clobetasol, possibly resulting in a "supraphysiologic exposure." Subsequently, our patient developed an exacerbation of activephase symptoms of schizophrenia. After clobetasol administration was reduced, these active phase symptoms dissipated. PMID: 29164927 [PubMed - as supplied by publisher] (Source: Clinical Schizophrenia and Related Psychoses)
Source: Clinical Schizophrenia and Related Psychoses - November 23, 2017 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

Clozapine, Diabetes Mellitus, Cardiovascular Risk and Mortality: Results of a 21-year Naturalistic Study in Patients with Schizophrenia and Schizoaffective Disorder.
Authors: Nemani KL, Greene MC, Ulloa M, Vincenzi B, Copeland PM, Al-Khadari S, Henderson DC Abstract The goal of this 21-year naturalistic study of clozapine treated patients was to examine the cardiovascular risk factors following clozapine initiation and resultant mortality estimates from cardiovascular disease. Data was collected from medical records of clozapine treated patients with schizophrenia or schizoaffective disorder from January 1992 to February 2012. Demographics, clozapine dosage and laboratory results were extracted at 12-month intervals. At clozapine initiation, the mean age of 96 patients...
Source: Clinical Schizophrenia and Related Psychoses - November 23, 2017 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

Psychosis as a sequelae of paraneoplastic syndrome in Small- Cell Lung Carcinoma: A psycho-neuroendocrine interface.
Authors: Wilkins CM, Johnson VL, Fargason RE, Birur B Abstract In 2013 more than 150,000 Americans died from all types of lung cancer. Small cell lung cancer (SCLC) represents about 13% of all lung cancers and is notoriously associated with paraneoplastic syndromes (PNS). Here we present an interesting case of psychosis associated with one such PNS-- ectopic Cushing syndrome of SCLC. A 56 year old African-American male with no prior psychiatric history who was diagnosed with SCLC two months prior, presented to the ER for treatment of a right arm laceration he sustained while fighting off attackers, with hi...
Source: Clinical Schizophrenia and Related Psychoses - November 23, 2017 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research

Relapse Risk Assessment for Schizophrenia Patients (RASP): a New Self-Report Screening Tool.
CONCLUSION: The reliability and validity data presented support the use of RASP in settings where addition of a brief self-report assessment of relapse risk among patients with schizophrenia may be of benefit. Ease of use and scoring and the ability to administer without clinical supervision allows for routine administration and assessment of relapse risk. PMID: 29164930 [PubMed - as supplied by publisher] (Source: Clinical Schizophrenia and Related Psychoses)
Source: Clinical Schizophrenia and Related Psychoses - November 23, 2017 Category: Psychiatry Tags: Clin Schizophr Relat Psychoses Source Type: research