Cure Is Possible: Extensively Metastatic HER2-Positive Gastric Carcinoma with 5 years of Complete Remission after Therapy with the FLOT Regimen and Trastuzumab
In conclusion, Trastuzumab in combination with FLOT may have curative potential even for metastatic stages of HER-2-positive GC.Case Rep Gastroenterol 2022;16:80 –88 (Source: Case Reports in Gastroenterology)
Source: Case Reports in Gastroenterology - February 17, 2022 Category: Gastroenterology Source Type: research
Successful Treatment of Pancreatic Fistula Following Surgery for Congenital Biliary Dilatation with Endoscopic Ultrasound-Guided Transduodenal Drainage
Despite improvements in surgical techniques and perioperative management, postoperative pancreatic fistula (PF) is often difficult to treat and can be fatal due to various complications without effective drainage. Here, we report a case of PF following surgery for congenital biliary dilatation (CBD) successfully managed by endoscopic ultrasound (EUS)-guided transduodenal drainage. A 55-year-old woman underwent extrahepatic bile duct resection, including the gallbladder, and biliary tract reconstruction for CBD. On the 10th postoperative day (POD), computed tomography (CT) showed fluid retention observed from the upper edge...
Source: Case Reports in Gastroenterology - February 14, 2022 Category: Gastroenterology Source Type: research
Intracholecystic Papillary Neoplasm Localized to the Cystic Duct: A Case Report
Intracholecystic papillary neoplasm (ICPN) of the gallbladder is a premalignant lesion. An ICPN arising from the cystic duct is rare. A woman in her 60s exhibited dilatation of the common bile duct on computed tomography (CT) performed for screening of respiratory disease. The CT revealed an enhancing mass, 3.3 cm in diameter, in the cystic duct. Endoscopic ultrasonography showed a well-demarcated, hyperechoic mass in the dilated cystic duct. Endoscopic retrograde cholangiography showed that the common bile duct was slightly retracted by the dilated cystic duct. Cytological analysis of the bile juice did not show any evide...
Source: Case Reports in Gastroenterology - February 14, 2022 Category: Gastroenterology Source Type: research
ADPKD, COVID-19, and Apixaban: The Treacherous Intracystic Bleeding – A Letter on Apixaban Causing Hepatic Cystic Bleeding by Shehi et al.
Case Rep Gastroenterol 2022;16:62 –65 (Source: Case Reports in Gastroenterology)
Source: Case Reports in Gastroenterology - February 14, 2022 Category: Gastroenterology Source Type: research
Acute Cholangitis Secondary to a Clogged Biliary Stent: A Review on the Cause of Clogging and the Appropriate Time of Replacement
Choledocholithiasis is preferably treated by endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy and stone removal, to reduce the risk for acute cholangitis. Frequently, patients who are ill, surgically unfit, or unable to undergo stone extraction during the index procedure underwent antibacterial treatment and temporary biliary stenting via ERCP to prevent biliary sepsis and septic shock. After a period of convalescence, a repeat ERCP is scheduled to clear the bile duct and remove the stent, followed by laparoscopic cholecystectomy to complete the treatment circuit. Cholangitis may often recur in pat...
Source: Case Reports in Gastroenterology - February 14, 2022 Category: Gastroenterology Source Type: research
Utilizing Percutaneous Cholecystostomy Tube as a Temporary Minimally Invasive Approach for Acute Cholecystitis during Third Trimester of a High-Risk Pregnancy
We present a case of a high-risk pregnancy involving a 41-year-old woman at the 34th week of gestation with a dichorionic-diamniotic-twin gestation with signs and symptoms of acute cholecystitis. Given the patient ’s high-risk status, a less intensive intervention, PCT, was performed for gallbladder decompression. An interval LC was performed on postpartum day 4 after caesarean section. Current surgical guidelines suggest that laparoscopy can be safely used to treat biliary disease during pregnancy in all t rimesters. Although rarely used as a first-line intervention for gallbladder disease, PCT is an important minimally...
Source: Case Reports in Gastroenterology - February 14, 2022 Category: Gastroenterology Source Type: research
Transient Small-Bowel Intussusception Unmasking Adult Celiac Disease
We report a case of adult intussusception as the first manifestation of CD. A 28-year-old nonalcoholic and nonsmoker, previously healthy man, presented to the emergency department with a 1-week history of progressive diffuse abdominal pain associated with abdominal distension, nausea, vomiting, diarrhea, and 7 kg weight loss. The physical exam was remarkable for thin body habitus with no lymphadenopathy. Laboratory testing was significant for hypochromic microcytic anemia, AST 214 IU/L, ALT 217 IU/L, alkaline phosphatase 183 IU/L, and INR 2.9. An abdominal radiograph showed distended gas-filled small- and large-bowel loops...
Source: Case Reports in Gastroenterology - February 14, 2022 Category: Gastroenterology Source Type: research
A Case of Fifteen Simultaneous Rectal Neuroendocrine Tumors and Endocrine Cell Micronests Resected by Both Endoscopic Treatments and Surgery
Conclusions:We herein report a case involving a patient with 15 rectal NETs and ECMs. We reviewed our experience with multiple rectal NETs, and the rate of multiple rectal NETs was 7.1%. Endoscopists should consider that multiple lesions may be present in cases of rectal NET and be aware that some cannot be detected endoscopically.Case Rep Gastroenterol 2022;16:37 –43 (Source: Case Reports in Gastroenterology)
Source: Case Reports in Gastroenterology - February 14, 2022 Category: Gastroenterology Source Type: research
Laparoscopic Triple Segmental Bowel Resection for Endometriosis Revealed by Rectal Obstruction during Infertility Treatment
Intestinal endometriosis is a benign disease characterized by ectopic growth of the endometrium and causes extensive fibrosis and adhesions in response to repeated episodes of bleeding and inflammation with the menstrual cycle. We encountered a rare case of intestinal endometriosis that caused complete rectal obstruction in a 34-year-old woman undergoing infertility treatment. Colonoscopy showed rectal stenosis and obstruction but no evidence of a tumor. Bowel obstruction due to endometriosis was diagnosed based on the history and imaging findings. Transanal decompression was performed. Subsequent laparoscopic surgery reve...
Source: Case Reports in Gastroenterology - February 10, 2022 Category: Gastroenterology Source Type: research
Primary Sclerosing Cholangitis Complicated with Aphthoid Colitis Difficult to Diagnose from IgG4-Related Sclerosing Cholangitis
A 19-year-old man visited our hospital because of diarrhea and blood and liver dysfunction. Magnetic and endoscopic retrograde cholangiography revealed diffuse narrowing of the common biliary tract and intrahepatic biliary tract. A biopsy specimen from the narrowed area of the common biliary tract revealed IgG4-related sclerosing cholangitis (IgG4-SC). Colonoscopy showed multiple aphthoid colitis. He was treated with corticosteroids, and the levels of hepatobiliary enzymes, IgG, and IgG4 gradually decreased. This is an extremely rare case of colitis in which the patient had a phenotype of sclerosing cholangitis similar to ...
Source: Case Reports in Gastroenterology - February 7, 2022 Category: Gastroenterology Source Type: research
Pre-Existing Microbiome Signature in a SARS-CoV-2 Discordant Family
Our index patient is a 19-year-old man with Crohn ’s disease. After developing symptoms consistent with COVID-19, he, his 62-year-old father, and 14-year-old sister tested positive for SARS-CoV-2 in May 2020. Despite a shared household, his 50-year-old mother with a history of asthma and his healthy brother and sister-in-law (a married couple) re mained negative. The index patient and his mother had undergone microbiome analysis in May 2019, following his brother and his sister-in-law in November 2020. We observed significant differences between the fecal microbiota of the SARS-CoV-2-positive son and those of his healthy...
Source: Case Reports in Gastroenterology - February 7, 2022 Category: Gastroenterology Source Type: research
Erratum
Case Rep Gastroenterol 2022;16:14 (Source: Case Reports in Gastroenterology)
Source: Case Reports in Gastroenterology - January 21, 2022 Category: Gastroenterology Source Type: research
Adenocarcinoma of the Gastroesophageal Junction Masquerading as Mallory-Weiss Syndrome
Mallory-Weiss syndrome (MWS) is a relatively uncommon cause of upper gastrointestinal bleeding. While most cases can be managed conservatively, frequent transfusions or endoscopic hemostasis may be required in some cases. A 74-year-old man presented with hematemesis triggered by coughing. He had a history of violent chronic cough due to chronic obstructive pulmonary disease and was placed on aspirin and warfarin after multiple percutaneous coronary interventions and aortic valve replacement. Emergency esophagogastroduodenoscopy (EGD) revealed a mucosal tear in the gastroesophageal junction (GEJ) consistent with MWS which w...
Source: Case Reports in Gastroenterology - January 17, 2022 Category: Gastroenterology Source Type: research
Cavernous Gastric Hemangioma as an Unusual Cause of Upper Gastrointestinal Bleeding in a Young Woman
We describe a 21-year-old woman who presented with epigastric pain and one episode of 250 mL hematemesis earlier that morning. Under the impression of an upper gastrointestinal bleed due to peptic ulcer disease, esophagogastroduodenoscopy was performed which revealed a 5-cm blood clot-like mass similar in appearance to that of a II-b peptic ulcer, but the presence of a bridging fold led to the suspicion of a possible submucosal tumor. Dynamic computerized tomography scan showed similar findings, and the patient was referred for surgical intervention. Laparoscopic distal gastrectomy was performed with the final diagnosis of...
Source: Case Reports in Gastroenterology - January 10, 2022 Category: Gastroenterology Source Type: research
A Rare Cause of Gastric Variceal Bleeding
A 68-year-old woman with stage III colon cancer status after right hemicolectomy and adjuvant FOLFOX (5-fluorouracil/leucovorin/oxaliplatin) chemotherapy was hospitalized for melena and found to have new-onset esophageal and gastric varices on esophagogastroduodenoscopy. Her workup did not reveal an underlying liver disease, but her liver biopsy showed noncirrhotic portal hypertension from obliterative portal venopathy (OPV). The development of OPV is likely from her use of oxaliplatin-based chemotherapy.Case Rep Gastroenterol 2021;15:1008 –1012 (Source: Case Reports in Gastroenterology)
Source: Case Reports in Gastroenterology - December 30, 2021 Category: Gastroenterology Source Type: research
