Efficient Estimation under Data Fusion
We describe potential gains in efficiency that can arise from fusing these data sources together in a single analysis, which we characterize by a reduction in the semiparametric efficiency bound. We also provide a general means to construct estimators that achieve these bounds. In numerical simulations, we illustrate marked improvements in efficiency from using our proposed estimators rather than their natural alternatives. Finally, we illustrate the magnitude of efficiency gains that can be realized in vaccine immunogenicity studies by fusing data from two HIV vaccine trials.PMID:37982010 | PMC:PMC10653189 | DOI:10.1093/b...
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Sijia Li Alex Luedtke Source Type: research

Discussion of 'Statistical inference for streamed longitudinal data'
Biometrika. 2023 Nov 15;110(4):867-869. doi: 10.1093/biomet/asad043. eCollection 2023 Dec.NO ABSTRACTPMID:37981957 | PMC:PMC10651177 | DOI:10.1093/biomet/asad043 (Source: Biometrika)
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Yang Ning Jingyi Duan Source Type: research

Efficient Estimation under Data Fusion
We describe potential gains in efficiency that can arise from fusing these data sources together in a single analysis, which we characterize by a reduction in the semiparametric efficiency bound. We also provide a general means to construct estimators that achieve these bounds. In numerical simulations, we illustrate marked improvements in efficiency from using our proposed estimators rather than their natural alternatives. Finally, we illustrate the magnitude of efficiency gains that can be realized in vaccine immunogenicity studies by fusing data from two HIV vaccine trials.PMID:37982010 | PMC:PMC10653189 | DOI:10.1093/b...
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Sijia Li Alex Luedtke Source Type: research

Discussion of 'Statistical inference for streamed longitudinal data'
Biometrika. 2023 Nov 15;110(4):867-869. doi: 10.1093/biomet/asad043. eCollection 2023 Dec.NO ABSTRACTPMID:37981957 | PMC:PMC10651177 | DOI:10.1093/biomet/asad043 (Source: Biometrika)
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Yang Ning Jingyi Duan Source Type: research

Efficient Estimation under Data Fusion
We describe potential gains in efficiency that can arise from fusing these data sources together in a single analysis, which we characterize by a reduction in the semiparametric efficiency bound. We also provide a general means to construct estimators that achieve these bounds. In numerical simulations, we illustrate marked improvements in efficiency from using our proposed estimators rather than their natural alternatives. Finally, we illustrate the magnitude of efficiency gains that can be realized in vaccine immunogenicity studies by fusing data from two HIV vaccine trials.PMID:37982010 | PMC:PMC10653189 | DOI:10.1093/b...
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Sijia Li Alex Luedtke Source Type: research

Discussion of 'Statistical inference for streamed longitudinal data'
Biometrika. 2023 Nov 15;110(4):867-869. doi: 10.1093/biomet/asad043. eCollection 2023 Dec.NO ABSTRACTPMID:37981957 | PMC:PMC10651177 | DOI:10.1093/biomet/asad043 (Source: Biometrika)
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Yang Ning Jingyi Duan Source Type: research

Efficient Estimation under Data Fusion
We describe potential gains in efficiency that can arise from fusing these data sources together in a single analysis, which we characterize by a reduction in the semiparametric efficiency bound. We also provide a general means to construct estimators that achieve these bounds. In numerical simulations, we illustrate marked improvements in efficiency from using our proposed estimators rather than their natural alternatives. Finally, we illustrate the magnitude of efficiency gains that can be realized in vaccine immunogenicity studies by fusing data from two HIV vaccine trials.PMID:37982010 | PMC:PMC10653189 | DOI:10.1093/b...
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Sijia Li Alex Luedtke Source Type: research

Discussion of 'Statistical inference for streamed longitudinal data'
Biometrika. 2023 Nov 15;110(4):867-869. doi: 10.1093/biomet/asad043. eCollection 2023 Dec.NO ABSTRACTPMID:37981957 | PMC:PMC10651177 | DOI:10.1093/biomet/asad043 (Source: Biometrika)
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Yang Ning Jingyi Duan Source Type: research

Efficient Estimation under Data Fusion
We describe potential gains in efficiency that can arise from fusing these data sources together in a single analysis, which we characterize by a reduction in the semiparametric efficiency bound. We also provide a general means to construct estimators that achieve these bounds. In numerical simulations, we illustrate marked improvements in efficiency from using our proposed estimators rather than their natural alternatives. Finally, we illustrate the magnitude of efficiency gains that can be realized in vaccine immunogenicity studies by fusing data from two HIV vaccine trials.PMID:37982010 | PMC:PMC10653189 | DOI:10.1093/b...
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Sijia Li Alex Luedtke Source Type: research

Discussion of 'Statistical inference for streamed longitudinal data'
Biometrika. 2023 Nov 15;110(4):867-869. doi: 10.1093/biomet/asad043. eCollection 2023 Dec.NO ABSTRACTPMID:37981957 | PMC:PMC10651177 | DOI:10.1093/biomet/asad043 (Source: Biometrika)
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Yang Ning Jingyi Duan Source Type: research

Efficient Estimation under Data Fusion
We describe potential gains in efficiency that can arise from fusing these data sources together in a single analysis, which we characterize by a reduction in the semiparametric efficiency bound. We also provide a general means to construct estimators that achieve these bounds. In numerical simulations, we illustrate marked improvements in efficiency from using our proposed estimators rather than their natural alternatives. Finally, we illustrate the magnitude of efficiency gains that can be realized in vaccine immunogenicity studies by fusing data from two HIV vaccine trials.PMID:37982010 | PMC:PMC10653189 | DOI:10.1093/b...
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Sijia Li Alex Luedtke Source Type: research

Discussion of 'Statistical inference for streamed longitudinal data'
Biometrika. 2023 Nov 15;110(4):867-869. doi: 10.1093/biomet/asad043. eCollection 2023 Dec.NO ABSTRACTPMID:37981957 | PMC:PMC10651177 | DOI:10.1093/biomet/asad043 (Source: Biometrika)
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Yang Ning Jingyi Duan Source Type: research

Efficient Estimation under Data Fusion
We describe potential gains in efficiency that can arise from fusing these data sources together in a single analysis, which we characterize by a reduction in the semiparametric efficiency bound. We also provide a general means to construct estimators that achieve these bounds. In numerical simulations, we illustrate marked improvements in efficiency from using our proposed estimators rather than their natural alternatives. Finally, we illustrate the magnitude of efficiency gains that can be realized in vaccine immunogenicity studies by fusing data from two HIV vaccine trials.PMID:37982010 | PMC:PMC10653189 | DOI:10.1093/b...
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Sijia Li Alex Luedtke Source Type: research

Discussion of 'Statistical inference for streamed longitudinal data'
Biometrika. 2023 Nov 15;110(4):867-869. doi: 10.1093/biomet/asad043. eCollection 2023 Dec.NO ABSTRACTPMID:37981957 | PMC:PMC10651177 | DOI:10.1093/biomet/asad043 (Source: Biometrika)
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Yang Ning Jingyi Duan Source Type: research

Efficient Estimation under Data Fusion
We describe potential gains in efficiency that can arise from fusing these data sources together in a single analysis, which we characterize by a reduction in the semiparametric efficiency bound. We also provide a general means to construct estimators that achieve these bounds. In numerical simulations, we illustrate marked improvements in efficiency from using our proposed estimators rather than their natural alternatives. Finally, we illustrate the magnitude of efficiency gains that can be realized in vaccine immunogenicity studies by fusing data from two HIV vaccine trials.PMID:37982010 | PMC:PMC10653189 | DOI:10.1093/b...
Source: Biometrika - November 20, 2023 Category: Biotechnology Authors: Sijia Li Alex Luedtke Source Type: research