Sparse self-attention aggregation networks for neural sequence slice interpolation
Microscopic imaging is a crucial technology for visualizing neural and tissue structures. Large-area defects inevitably occur during the imaging process of electron microscope (EM) serial slices, which lead to... (Source: BioData Mining)
Source: BioData Mining - February 1, 2021 Category: Bioinformatics Authors: Zejin Wang, Jing Liu, Xi Chen, Guoqing Li and Hua Han Tags: Research Source Type: research
A comparison of methods for interpreting random forest models of genetic association in the presence of non-additive interactions
Non-additive interactions among genes are frequently associated with a number of phenotypes, including known complex diseases such as Alzheimer ’s, diabetes, and cardiovascular disease. Detecting interactions r... (Source: BioData Mining)
Source: BioData Mining - January 29, 2021 Category: Bioinformatics Authors: Alena Orlenko and Jason H. Moore Tags: Research Source Type: research
Empowering the data science scientist
(Source: BioData Mining)
Source: BioData Mining - January 23, 2021 Category: Bioinformatics Authors: Jason H. Moore Tags: Editorial Source Type: research
Privacy-preserving chi-squared test of independence for small samples
The importance of privacy protection in analyses of personal data, such as genome-wide association studies (GWAS), has grown in recent years. GWAS focuses on identifying single-nucleotide polymorphisms (SNPs) ... (Source: BioData Mining)
Source: BioData Mining - January 22, 2021 Category: Bioinformatics Authors: Yuichi Sei and Akihiko Ohsuga Tags: Research Source Type: research
Feature selection using distributions of orthogonal PLS regression vectors in spectral data
Feature selection, which is important for successful analysis of chemometric data, aims to produce parsimonious and predictive models. Partial least squares (PLS) regression is one of the main methods in chemo... (Source: BioData Mining)
Source: BioData Mining - January 22, 2021 Category: Bioinformatics Authors: Geonseok Lee and Kichun Lee Tags: Methodology Source Type: research
Mechanistic modeling of the SARS-CoV-2 disease map
Here we present a web interface that implements a comprehensive mechanistic model of the SARS-CoV-2 disease map. In this framework, the detailed activity of the human signaling circuits related to the viral in... (Source: BioData Mining)
Source: BioData Mining - January 21, 2021 Category: Bioinformatics Authors: Kinza Rian, Marina Esteban-Medina, Marta R. Hidalgo, Cankut Çubuk, Matias M. Falco, Carlos Loucera, Devrim Gunyel, Marek Ostaszewski, María Peña-Chilet and Joaquín Dopazo Tags: Short report Source Type: research
An efficient computational method for predicting drug-target interactions using weighted extreme learning machine and speed up robot features
Prediction of novel Drug –Target interactions (DTIs) plays an important role in discovering new drug candidates and finding new proteins to target. In consideration of the time-consuming and expensive of experi... (Source: BioData Mining)
Source: BioData Mining - January 20, 2021 Category: Bioinformatics Authors: Ji-Yong An, Fan-Rong Meng and Zi-Ji Yan Tags: Research Source Type: research
COVID-TRACK: world and USA SARS-COV-2 testing and COVID-19 tracking
The COVID-19 pandemic has caused major health and socio-economic disruptions worldwide. Accurate investigation of emerging data is crucial to inform policy makers as they construct viral mitigation strategies.... (Source: BioData Mining)
Source: BioData Mining - January 20, 2021 Category: Bioinformatics Authors: Ye Emma Zohner and Jeffrey S. Morris Tags: Software article Source Type: research
LightCUD: a program for diagnosing IBD based on human gut microbiome data
The diagnosis of inflammatory bowel disease (IBD) and discrimination between the types of IBD are clinically important. IBD is associated with marked changes in the intestinal microbiota. Advances in next-gene... (Source: BioData Mining)
Source: BioData Mining - January 19, 2021 Category: Bioinformatics Authors: Congmin Xu, Man Zhou, Zhongjie Xie, Mo Li, Xi Zhu and Huaiqiu Zhu Tags: Research Source Type: research
Identification of the active substances and mechanisms of ginger for the treatment of colon cancer based on network pharmacology and molecular docking
This study was aimed to identify the... (Source: BioData Mining)
Source: BioData Mining - January 11, 2021 Category: Bioinformatics Authors: Meng-Meng Zhang, Dan Wang, Feng Lu, Rong Zhao, Xun Ye, Lin He, Li Ai and Chun-Jie Wu Tags: Research Source Type: research
Comparative analysis, applications, and interpretation of electronic health record-based stroke phenotyping methods
Accurate identification of acute ischemic stroke (AIS) patient cohorts is essential for a wide range of clinical investigations. Automated phenotyping methods that leverage electronic health records (EHRs) rep... (Source: BioData Mining)
Source: BioData Mining - December 7, 2020 Category: Bioinformatics Authors: Phyllis M. Thangaraj, Benjamin R. Kummer, Tal Lorberbaum, Mitchell S. V. Elkind and Nicholas P. Tatonetti Tags: Research Source Type: research
ISLAND: in-silico proteins binding affinity prediction using sequence information
Determining binding affinity in protein-protein interactions is important in the discovery and design of novel therapeutics and mutagenesis studies. Determination of binding affinity of proteins in the formati... (Source: BioData Mining)
Source: BioData Mining - November 25, 2020 Category: Bioinformatics Authors: Wajid Arshad Abbasi, Adiba Yaseen, Fahad Ul Hassan, Saiqa Andleeb and Fayyaz Ul Amir Afsar Minhas Tags: Research Source Type: research
Exploring active ingredients and function mechanisms of Ephedra-bitter almond for prevention and treatment of Corona virus disease 2019 (COVID-19) based on network pharmacology
COVID-19 has caused a global pandemic, and there is no wonder drug for epidemic control at present. However, many clinical practices have shown that traditional Chinese medicine has played an important role in... (Source: BioData Mining)
Source: BioData Mining - November 10, 2020 Category: Bioinformatics Authors: Kai Gao, Yan-Ping Song and Anna Song Tags: Research Source Type: research
Ten important roles for academic leaders in data science
Data science has emerged as an important discipline in the era of big data and biological and biomedical data mining. As such, we have seen a rapid increase in the number of data science departments, research ... (Source: BioData Mining)
Source: BioData Mining - October 26, 2020 Category: Bioinformatics Authors: Jason H. Moore Tags: Editorial Source Type: research
Examining the effector mechanisms of Xuebijing injection on COVID-19 based on network pharmacology
Chinese medicine Xuebijing (XBJ) has proven to be effective in the treatment of mild coronavirus disease 2019 (COVID-19) cases. But the bioactive compounds and potential mechanisms of XBJ for COVID-19 preventi... (Source: BioData Mining)
Source: BioData Mining - October 16, 2020 Category: Bioinformatics Authors: Wen-jiang Zheng, Qian Yan, Yong-shi Ni, Shao-feng Zhan, Liu-liu Yang, Hong-fa Zhuang, Xiao-hong Liu and Yong Jiang Tags: Research Source Type: research
